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Uveal melanoma presenting as cataract and staphyloma.

Khetan V, Gupta K, Mohan ER, Gopal L - Indian J Ophthalmol (2009 May-Jun)

Bottom Line: The left eye was blind for six months.The ultrasound of the eye showed a large mass filling the superior, nasal and inferonasal vitreous cavity with high surface reflectivity and low to moderate internal reflectivity.Magnetic resonance imaging (MRI) confirmed the diagnosis of choroidal melanoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Vitreoretina and Ocular Oncology, Medical Research Foundation, Sankara Nethralaya, Chennai, India. drkhetan@yahoo.com

ABSTRACT
Blind eyes can harbor a choroidal melanoma. We report a case of uveal melanoma presenting as staphyloma and complicated cataract in a 45-year-old female. The left eye was blind for six months. She underwent comprehensive ocular examination but fundus examination was precluded due to total cataract. The ultrasound of the eye showed a large mass filling the superior, nasal and inferonasal vitreous cavity with high surface reflectivity and low to moderate internal reflectivity. Magnetic resonance imaging (MRI) confirmed the diagnosis of choroidal melanoma. The patient underwent extended enucleation and histopathology was consistent with uveal melanoma.

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Histopathological findings of the enucleated eyeball (H&E, ×20)
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Figure 0005: Histopathological findings of the enucleated eyeball (H&E, ×20)

Mentions: The histopathological examination showed a pigmented tumor mass arising from the anterior part of the choroid which was composed of pigment-bearing spindle cells and epithelioid cells. Multiple mitotic figures were seen [Figs. 5, 6]. Extrascleral extension was also noted histopathologically. Histopathological diagnosis of malignant melanoma of choroid of the mixed cell type was made. Six weeks postoperatively, the orbit was free of any tumor recurrence but the liver nodule enlarged and was confirmed as metastasis. The patient was advised palliative chemotherapy.


Uveal melanoma presenting as cataract and staphyloma.

Khetan V, Gupta K, Mohan ER, Gopal L - Indian J Ophthalmol (2009 May-Jun)

Histopathological findings of the enucleated eyeball (H&E, ×20)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2683430&req=5

Figure 0005: Histopathological findings of the enucleated eyeball (H&E, ×20)
Mentions: The histopathological examination showed a pigmented tumor mass arising from the anterior part of the choroid which was composed of pigment-bearing spindle cells and epithelioid cells. Multiple mitotic figures were seen [Figs. 5, 6]. Extrascleral extension was also noted histopathologically. Histopathological diagnosis of malignant melanoma of choroid of the mixed cell type was made. Six weeks postoperatively, the orbit was free of any tumor recurrence but the liver nodule enlarged and was confirmed as metastasis. The patient was advised palliative chemotherapy.

Bottom Line: The left eye was blind for six months.The ultrasound of the eye showed a large mass filling the superior, nasal and inferonasal vitreous cavity with high surface reflectivity and low to moderate internal reflectivity.Magnetic resonance imaging (MRI) confirmed the diagnosis of choroidal melanoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Vitreoretina and Ocular Oncology, Medical Research Foundation, Sankara Nethralaya, Chennai, India. drkhetan@yahoo.com

ABSTRACT
Blind eyes can harbor a choroidal melanoma. We report a case of uveal melanoma presenting as staphyloma and complicated cataract in a 45-year-old female. The left eye was blind for six months. She underwent comprehensive ocular examination but fundus examination was precluded due to total cataract. The ultrasound of the eye showed a large mass filling the superior, nasal and inferonasal vitreous cavity with high surface reflectivity and low to moderate internal reflectivity. Magnetic resonance imaging (MRI) confirmed the diagnosis of choroidal melanoma. The patient underwent extended enucleation and histopathology was consistent with uveal melanoma.

Show MeSH
Related in: MedlinePlus