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Modeling kinetics of subcellular disposition of chemicals.

Balaz S - Chem. Rev. (2009)

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Affiliation: Department of Pharmaceutical Sciences, College of Pharmacy, North Dakota State University, Fargo, North Dakota 58105, USA. stefan.balaz@ndsu.edu

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Nonequilibrium concentration−lipophilicity profiles for individual phases of a 10-compartment system of alternating aqueous and core phases at a constant time of distribution.(2089) Other details as in Figure 15. The compartment numbers are shown near the respective curves. The aqueous phases are denoted by the odd numbers and the bilayers are marked by even numbers, as in Figure 14 in section .
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fig18: Nonequilibrium concentration−lipophilicity profiles for individual phases of a 10-compartment system of alternating aqueous and core phases at a constant time of distribution.(2089) Other details as in Figure 15. The compartment numbers are shown near the respective curves. The aqueous phases are denoted by the odd numbers and the bilayers are marked by even numbers, as in Figure 14 in section .

Mentions: Meanings of the adjustable coefficients in eq 11 that describes the relationship between the subcellular concentrations c and lipophilicity expressed as the partition coefficients P. The slopes of the linear parts, relative to the coefficients A and Bi, are given in the upper part (all expressions are to be multiplied by the coefficient β). The positions of the curvatures are determined by the values of the coefficients Ci.(2089)


Modeling kinetics of subcellular disposition of chemicals.

Balaz S - Chem. Rev. (2009)

Nonequilibrium concentration−lipophilicity profiles for individual phases of a 10-compartment system of alternating aqueous and core phases at a constant time of distribution.(2089) Other details as in Figure 15. The compartment numbers are shown near the respective curves. The aqueous phases are denoted by the odd numbers and the bilayers are marked by even numbers, as in Figure 14 in section .
© Copyright Policy - open-access - ccc-price
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2682929&req=5

fig18: Nonequilibrium concentration−lipophilicity profiles for individual phases of a 10-compartment system of alternating aqueous and core phases at a constant time of distribution.(2089) Other details as in Figure 15. The compartment numbers are shown near the respective curves. The aqueous phases are denoted by the odd numbers and the bilayers are marked by even numbers, as in Figure 14 in section .
Mentions: Meanings of the adjustable coefficients in eq 11 that describes the relationship between the subcellular concentrations c and lipophilicity expressed as the partition coefficients P. The slopes of the linear parts, relative to the coefficients A and Bi, are given in the upper part (all expressions are to be multiplied by the coefficient β). The positions of the curvatures are determined by the values of the coefficients Ci.(2089)

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmaceutical Sciences, College of Pharmacy, North Dakota State University, Fargo, North Dakota 58105, USA. stefan.balaz@ndsu.edu

Show MeSH