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My approach to interstitial lung disease using clinical, radiological and histopathological patterns.

Leslie KO - J. Clin. Pathol. (2009)

Bottom Line: The complex world of interstitial lung disease presents nearly insurmountable challenges to the general surgical pathologist faced with a lung biopsy in this setting.The pathology is often inflammatory and always requires clinical and radiological context for a relevant and clinically useful histopathological diagnosis.A pattern-based histopathological approach to interstitial lung disease provides a "map" for the general pathologist to navigate this area successfully, especially so when used with aid of the clinical and radiological patterns of presentation.

View Article: PubMed Central - PubMed

Affiliation: Division of Anatomic Pathology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA. leslie.kevin@mayo.edu

ABSTRACT
The complex world of interstitial lung disease presents nearly insurmountable challenges to the general surgical pathologist faced with a lung biopsy in this setting. The pathology is often inflammatory and always requires clinical and radiological context for a relevant and clinically useful histopathological diagnosis. A pattern-based histopathological approach to interstitial lung disease provides a "map" for the general pathologist to navigate this area successfully, especially so when used with aid of the clinical and radiological patterns of presentation.

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Related in: MedlinePlus

Pattern 2 fibrosis. Fibrosis in the lung parenchyma should be diagnosed only when it is dense, and never in the transbronchial biopsy specimen. Note the distortion of the alveolar parenchyma and fusion of alveolar walls.
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CPT-62-05-0387-f07: Pattern 2 fibrosis. Fibrosis in the lung parenchyma should be diagnosed only when it is dense, and never in the transbronchial biopsy specimen. Note the distortion of the alveolar parenchyma and fusion of alveolar walls.

Mentions: Basic elements of the pattern: dense collagen deposition in the lung parenchyma, often accompanied by some degree of structural remodelling with alveolar loss (fig 7).


My approach to interstitial lung disease using clinical, radiological and histopathological patterns.

Leslie KO - J. Clin. Pathol. (2009)

Pattern 2 fibrosis. Fibrosis in the lung parenchyma should be diagnosed only when it is dense, and never in the transbronchial biopsy specimen. Note the distortion of the alveolar parenchyma and fusion of alveolar walls.
© Copyright Policy - openaccess
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2668105&req=5

CPT-62-05-0387-f07: Pattern 2 fibrosis. Fibrosis in the lung parenchyma should be diagnosed only when it is dense, and never in the transbronchial biopsy specimen. Note the distortion of the alveolar parenchyma and fusion of alveolar walls.
Mentions: Basic elements of the pattern: dense collagen deposition in the lung parenchyma, often accompanied by some degree of structural remodelling with alveolar loss (fig 7).

Bottom Line: The complex world of interstitial lung disease presents nearly insurmountable challenges to the general surgical pathologist faced with a lung biopsy in this setting.The pathology is often inflammatory and always requires clinical and radiological context for a relevant and clinically useful histopathological diagnosis.A pattern-based histopathological approach to interstitial lung disease provides a "map" for the general pathologist to navigate this area successfully, especially so when used with aid of the clinical and radiological patterns of presentation.

View Article: PubMed Central - PubMed

Affiliation: Division of Anatomic Pathology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA. leslie.kevin@mayo.edu

ABSTRACT
The complex world of interstitial lung disease presents nearly insurmountable challenges to the general surgical pathologist faced with a lung biopsy in this setting. The pathology is often inflammatory and always requires clinical and radiological context for a relevant and clinically useful histopathological diagnosis. A pattern-based histopathological approach to interstitial lung disease provides a "map" for the general pathologist to navigate this area successfully, especially so when used with aid of the clinical and radiological patterns of presentation.

Show MeSH
Related in: MedlinePlus