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Aortic distensibility and coronary artery bypass graft patency.

Ozdemir B, Biçer M, Ozdemir L, Baran I, Kaderli AA, Sentürk T, Emül A, Yetgin ZA, Güllülü S, Aydinlar A - J Cardiothorac Surg (2009)

Bottom Line: Coronary artery disease has been found to be substantially associated with increased aortic stiffness.The aortic distensibility did not differ in cases with and without saphenous graft occlusion (p > 0.05).We also evaluated the data for cut-off values of 50 and 70 mmHg of pulse pressure and did not see any significant difference between the groups in terms of saphenous or LIMA grafts.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cardiology Department, Uludağ University Medical Faculty, Görükle, Bursa, Turkey. buloz2@yahoo.com

ABSTRACT

Background: Aortic distensibility is an elasticity index of the aorta, and reflects aortic stiffness. Coronary artery disease has been found to be substantially associated with increased aortic stiffness. In this study we aimed to retrospectively analyze the association of angiographically determined aortic distensibility with the patency rates of coronary bypass grafts

Methods: The study was conducted in the Cardiology department of the Applied Research Centre for Health of Uludağ University. The coronary angiograms of 53 consecutive coronary bypass patients were analysed retrospectively. Aortic distensibility was calculated using the formula: 2 x (change in aortic diameter)/(diastolic aortic diameter) x (change in aortic pressure). The number of stenosed and patent bypass grafts and the patient characteristics like age, risk factors were noted.

Results: There were 44 male (83%) and 9 female (17%) cases. Eighteen cases had only one saphenous vein grafting. The number of cases with two, three and four saphenous grafting were 18, 11 and 1; respectively. In the control angiograms the number of cases with one, two, three and four saphenous vein graft obstruction were 15 (31.3%), 7 (14.6%), 1 (2.1%) and 1 (2.1%) respectively. The aortic distensibility did not differ in cases with and without saphenous graft occlusion (p > 0.05). Also left internal mammary artery (LIMA) graft patency was not related to the distensibility of the aorta (p > 0.05). We also evaluated the data for cut-off values of 50 and 70 mmHg of pulse pressure and did not see any significant difference between the groups in terms of saphenous or LIMA grafts.

Conclusion: In this study we failed to show association of angiographically determined aortic distensibility with coronary bypass graft patency in consecutive 53 patients with coronary artery bypass graft surgery (CABG).

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The comparison of aortic distensibility) in cases with and without saphenous graft. The comparison of aortic distensibility (cm2.dyne-1) in cases with and without saphenous graft anastomosis revealed no statistically significant difference (p > 0.05)
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Figure 1: The comparison of aortic distensibility) in cases with and without saphenous graft. The comparison of aortic distensibility (cm2.dyne-1) in cases with and without saphenous graft anastomosis revealed no statistically significant difference (p > 0.05)

Mentions: The aortic distensibility did not differ in cases with and without saphenous graft occlusion (p > 0.05) (Figure 1). Also LIMA graft patency was not related to the distensibility of the aorta (p > 0.05) (Figure 2). When the individual anastomoses were analysed (territories of left anterior descending artery, circumflex and right coronary arteries) there was no significant difference in terms of aortic distensibility and pulse pressure. We also had a cut off value of 3.5 (cm2.dyne-1) for aortic distensibility and compared the cases with and without saphenous and/or LIMA graft occlusion. Again there was no statistically significant difference between the groups. A cut-off point for pulse pressure of 50 mmHg was also used for statistical analysis about the patency rates of LIMA and saphenous grafts and there was no statistically significant difference between the groups (p > 0.05) (Figure 3-a). We divided the cases into groups as having aortic pulse pressure lower and higher than 70 mmHg and then checked for patency rates of saphenous and LIMA grafts again. This analysis also did not reveal a statistically significant difference between the groups (p > 0.05) (Figure 3-b).


Aortic distensibility and coronary artery bypass graft patency.

Ozdemir B, Biçer M, Ozdemir L, Baran I, Kaderli AA, Sentürk T, Emül A, Yetgin ZA, Güllülü S, Aydinlar A - J Cardiothorac Surg (2009)

The comparison of aortic distensibility) in cases with and without saphenous graft. The comparison of aortic distensibility (cm2.dyne-1) in cases with and without saphenous graft anastomosis revealed no statistically significant difference (p > 0.05)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2667388&req=5

Figure 1: The comparison of aortic distensibility) in cases with and without saphenous graft. The comparison of aortic distensibility (cm2.dyne-1) in cases with and without saphenous graft anastomosis revealed no statistically significant difference (p > 0.05)
Mentions: The aortic distensibility did not differ in cases with and without saphenous graft occlusion (p > 0.05) (Figure 1). Also LIMA graft patency was not related to the distensibility of the aorta (p > 0.05) (Figure 2). When the individual anastomoses were analysed (territories of left anterior descending artery, circumflex and right coronary arteries) there was no significant difference in terms of aortic distensibility and pulse pressure. We also had a cut off value of 3.5 (cm2.dyne-1) for aortic distensibility and compared the cases with and without saphenous and/or LIMA graft occlusion. Again there was no statistically significant difference between the groups. A cut-off point for pulse pressure of 50 mmHg was also used for statistical analysis about the patency rates of LIMA and saphenous grafts and there was no statistically significant difference between the groups (p > 0.05) (Figure 3-a). We divided the cases into groups as having aortic pulse pressure lower and higher than 70 mmHg and then checked for patency rates of saphenous and LIMA grafts again. This analysis also did not reveal a statistically significant difference between the groups (p > 0.05) (Figure 3-b).

Bottom Line: Coronary artery disease has been found to be substantially associated with increased aortic stiffness.The aortic distensibility did not differ in cases with and without saphenous graft occlusion (p > 0.05).We also evaluated the data for cut-off values of 50 and 70 mmHg of pulse pressure and did not see any significant difference between the groups in terms of saphenous or LIMA grafts.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cardiology Department, Uludağ University Medical Faculty, Görükle, Bursa, Turkey. buloz2@yahoo.com

ABSTRACT

Background: Aortic distensibility is an elasticity index of the aorta, and reflects aortic stiffness. Coronary artery disease has been found to be substantially associated with increased aortic stiffness. In this study we aimed to retrospectively analyze the association of angiographically determined aortic distensibility with the patency rates of coronary bypass grafts

Methods: The study was conducted in the Cardiology department of the Applied Research Centre for Health of Uludağ University. The coronary angiograms of 53 consecutive coronary bypass patients were analysed retrospectively. Aortic distensibility was calculated using the formula: 2 x (change in aortic diameter)/(diastolic aortic diameter) x (change in aortic pressure). The number of stenosed and patent bypass grafts and the patient characteristics like age, risk factors were noted.

Results: There were 44 male (83%) and 9 female (17%) cases. Eighteen cases had only one saphenous vein grafting. The number of cases with two, three and four saphenous grafting were 18, 11 and 1; respectively. In the control angiograms the number of cases with one, two, three and four saphenous vein graft obstruction were 15 (31.3%), 7 (14.6%), 1 (2.1%) and 1 (2.1%) respectively. The aortic distensibility did not differ in cases with and without saphenous graft occlusion (p > 0.05). Also left internal mammary artery (LIMA) graft patency was not related to the distensibility of the aorta (p > 0.05). We also evaluated the data for cut-off values of 50 and 70 mmHg of pulse pressure and did not see any significant difference between the groups in terms of saphenous or LIMA grafts.

Conclusion: In this study we failed to show association of angiographically determined aortic distensibility with coronary bypass graft patency in consecutive 53 patients with coronary artery bypass graft surgery (CABG).

Show MeSH
Related in: MedlinePlus