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Mapping the history and current situation of research on John Cunningham virus - a bibliometric analysis.

Zheng HC, Yan L, Cui L, Guan YF, Takano Y - BMC Infect. Dis. (2009)

Bottom Line: Journal of Virology and Journal of Neurovirology respectively ranked to the first two highly-cited journals.JCV investigation mainly focused on its isolation and detection, as well as its correlation with PML and tumors.Establishment of transgenic animal model using JCV T antigen would be a hopeful and useful project in the further study.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Biochemistry and Molecular Biology, College of Basic Medicine, China Medical University, Shenyang, PR China. zheng_huachuan@hotmail.com

ABSTRACT

Background: John Cunningham virus (JCV) constitutes a family of polyoma viruses, which plays important roles in the progressive multifocal leukoencephalopathy (PML) and tumorigenesis. However, no bibliometric investigation has been reported to guide the researchers and potential readers.

Methods: Papers were collected from database Sci-expanded and Pubmed until May 22, 2008. The highly-productive authors, institutes and countries, highly-cited authors and journals were ranked. The highly-cited articles were subjected to co-citation and chronological analysis with highly-frequent MeSH words for co-occurrence analysis.

Results: Until now, 1785 articles about JCV were indexed in Sci-expanded and 1506 in Pubmed. The main document type was original article. USA, Japan and Italy were the largest three producers about JCV. Temple University published 128 papers and ranked the top, followed by University of Tokyo. Khalili K and Yogo Y became the core authors due to more than 20 documents produced. Journal of Neurovirology published more than 15 papers and ranked the top. Padgett BL and Berger JR were the first two highly-cited authors. Journal of Virology and Journal of Neurovirology respectively ranked to the first two highly-cited journals. These top highly-cited articles were divided into 5 aspects: (1) The correlation between JC virus and tumors; (2) Causal correlation of JCV with PML; (3) Polyoma virus infection and its related diseases in renal-allograft recipients; (4) Detection of JCV antibody, oncogene and its encoding protein; (5) Genetics and molecular biology of JCV. The MeSH/subheadings were classified into five groups: (1) JCV and virus infectious diseases; (2) JCV pathogenicity and pathological appearance of PML; (3) JCV isolation and detection; (4) Immunology of JCV and PML; (5) JCV genetics and tumors.

Conclusion: JCV investigation mainly focused on its isolation and detection, as well as its correlation with PML and tumors. Establishment of transgenic animal model using JCV T antigen would be a hopeful and useful project in the further study.

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Temporal distribution of production about JCV investigation.
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Figure 1: Temporal distribution of production about JCV investigation.

Mentions: Until May 22, 2008, 1785 articles about JCV were indexed in Sci-expanded with 62508 references and 1506(225 reviews) in Pubmed with 6435 major MeSH/subheading words. The literature about JCV was gradually rising from 3 articles in 1976 until 179 in 2006 as indicated in Figure 1. The average annual growth rate was 5.7 pieces in the period. According to document type, there were 1307 original articles (73.2%), 123 reviews (6.9%) and 209 meeting abstracts (11.7%) in all collected literature (Table 1). In overall 21 countries listed, USA, Japan, Italy and Germany were in order the largest four producers about JCV despite 62 countries included (Table 2). The overall 1245 institutes were mentioned to investigate JCV, among which Temple University of USA published 128 papers and ranked the top, followed by University of Tokyo, and National Institute of Neurological Disorder and Stroke subsequently. Fourteen of 21 (66.7%) core institutes come from USA with three core institutes in Italy (Table 3). Such 33 authors as Khalili K, Yogo Y and etc produced more than 20 documents in spite of all 4856 authors involved. There were 9 highly-produced scientists from Temple University and 6 from University of Tokyo, Japan, and 4 from National Institute of Neurological Disorder and Stroke, USA respectively (Table 4). As shown in Table 5, Journal of Neurovirology, Journal of Virology, Virology, Journal of Medical Virology, Journal of General Virology and so forth published more than 15 papers and were considered as the core journals although there existed JCV papers in 395 journals. These source journals mainly include the field of Virology, Neurosciences, Clinical Neurology, Immunology, Pathology, Oncology and so on (Table 6).


Mapping the history and current situation of research on John Cunningham virus - a bibliometric analysis.

Zheng HC, Yan L, Cui L, Guan YF, Takano Y - BMC Infect. Dis. (2009)

Temporal distribution of production about JCV investigation.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2667186&req=5

Figure 1: Temporal distribution of production about JCV investigation.
Mentions: Until May 22, 2008, 1785 articles about JCV were indexed in Sci-expanded with 62508 references and 1506(225 reviews) in Pubmed with 6435 major MeSH/subheading words. The literature about JCV was gradually rising from 3 articles in 1976 until 179 in 2006 as indicated in Figure 1. The average annual growth rate was 5.7 pieces in the period. According to document type, there were 1307 original articles (73.2%), 123 reviews (6.9%) and 209 meeting abstracts (11.7%) in all collected literature (Table 1). In overall 21 countries listed, USA, Japan, Italy and Germany were in order the largest four producers about JCV despite 62 countries included (Table 2). The overall 1245 institutes were mentioned to investigate JCV, among which Temple University of USA published 128 papers and ranked the top, followed by University of Tokyo, and National Institute of Neurological Disorder and Stroke subsequently. Fourteen of 21 (66.7%) core institutes come from USA with three core institutes in Italy (Table 3). Such 33 authors as Khalili K, Yogo Y and etc produced more than 20 documents in spite of all 4856 authors involved. There were 9 highly-produced scientists from Temple University and 6 from University of Tokyo, Japan, and 4 from National Institute of Neurological Disorder and Stroke, USA respectively (Table 4). As shown in Table 5, Journal of Neurovirology, Journal of Virology, Virology, Journal of Medical Virology, Journal of General Virology and so forth published more than 15 papers and were considered as the core journals although there existed JCV papers in 395 journals. These source journals mainly include the field of Virology, Neurosciences, Clinical Neurology, Immunology, Pathology, Oncology and so on (Table 6).

Bottom Line: Journal of Virology and Journal of Neurovirology respectively ranked to the first two highly-cited journals.JCV investigation mainly focused on its isolation and detection, as well as its correlation with PML and tumors.Establishment of transgenic animal model using JCV T antigen would be a hopeful and useful project in the further study.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Biochemistry and Molecular Biology, College of Basic Medicine, China Medical University, Shenyang, PR China. zheng_huachuan@hotmail.com

ABSTRACT

Background: John Cunningham virus (JCV) constitutes a family of polyoma viruses, which plays important roles in the progressive multifocal leukoencephalopathy (PML) and tumorigenesis. However, no bibliometric investigation has been reported to guide the researchers and potential readers.

Methods: Papers were collected from database Sci-expanded and Pubmed until May 22, 2008. The highly-productive authors, institutes and countries, highly-cited authors and journals were ranked. The highly-cited articles were subjected to co-citation and chronological analysis with highly-frequent MeSH words for co-occurrence analysis.

Results: Until now, 1785 articles about JCV were indexed in Sci-expanded and 1506 in Pubmed. The main document type was original article. USA, Japan and Italy were the largest three producers about JCV. Temple University published 128 papers and ranked the top, followed by University of Tokyo. Khalili K and Yogo Y became the core authors due to more than 20 documents produced. Journal of Neurovirology published more than 15 papers and ranked the top. Padgett BL and Berger JR were the first two highly-cited authors. Journal of Virology and Journal of Neurovirology respectively ranked to the first two highly-cited journals. These top highly-cited articles were divided into 5 aspects: (1) The correlation between JC virus and tumors; (2) Causal correlation of JCV with PML; (3) Polyoma virus infection and its related diseases in renal-allograft recipients; (4) Detection of JCV antibody, oncogene and its encoding protein; (5) Genetics and molecular biology of JCV. The MeSH/subheadings were classified into five groups: (1) JCV and virus infectious diseases; (2) JCV pathogenicity and pathological appearance of PML; (3) JCV isolation and detection; (4) Immunology of JCV and PML; (5) JCV genetics and tumors.

Conclusion: JCV investigation mainly focused on its isolation and detection, as well as its correlation with PML and tumors. Establishment of transgenic animal model using JCV T antigen would be a hopeful and useful project in the further study.

Show MeSH
Related in: MedlinePlus