Limits...
DICOM structured reporting and cancer clinical trials results.

Clunie DA - Cancer Inform (2007)

Bottom Line: DICOM is the ubiquitous standard for the interchange of images for both clinical use as well as research.It also has capabilities for the exchange of image-related information, including categorical and quantitative information derived from images.The use of DICOM Structured Reporting for the encoding and interchange of clinical trial results in a standard manner is reviewed.

View Article: PubMed Central - PubMed

Affiliation: RadPharm, Princeton, NJ 08540, USA. dclunie@dclunie.com

ABSTRACT
The use of biomarkers derived from radiological images as surrogate end-points in therapeutic cancer clinical trials is well established. DICOM is the ubiquitous standard for the interchange of images for both clinical use as well as research. It also has capabilities for the exchange of image-related information, including categorical and quantitative information derived from images. The use of DICOM Structured Reporting for the encoding and interchange of clinical trial results in a standard manner is reviewed.

No MeSH data available.


Related in: MedlinePlus

Illustrated is an outline for a clinical trials template organization that allows for one or more time points, one or more readers, and findings (lesions) that span multiple images.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
getmorefigures.php?uid=PMC2666949&req=5

f2-cin-04-33: Illustrated is an outline for a clinical trials template organization that allows for one or more time points, one or more readers, and findings (lesions) that span multiple images.

Mentions: A proposed outline of nested templates that would mimic the existing CAD templates to the extent possible yet introduce the specific concepts of time point and reader is shown in Figure 2. This proposal envisages that for each reader’s report on each time point there will be a single response assessment encoded as the reader’s findings, which will be supported by sub-findings categorized as target, non-target and new lesions. Aggregated information for target lesions, such as the sum of the longest diameter (SLD) or the sum of the product of diameters (SPD) will be encoded in the target lesion container template.


DICOM structured reporting and cancer clinical trials results.

Clunie DA - Cancer Inform (2007)

Illustrated is an outline for a clinical trials template organization that allows for one or more time points, one or more readers, and findings (lesions) that span multiple images.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC2666949&req=5

f2-cin-04-33: Illustrated is an outline for a clinical trials template organization that allows for one or more time points, one or more readers, and findings (lesions) that span multiple images.
Mentions: A proposed outline of nested templates that would mimic the existing CAD templates to the extent possible yet introduce the specific concepts of time point and reader is shown in Figure 2. This proposal envisages that for each reader’s report on each time point there will be a single response assessment encoded as the reader’s findings, which will be supported by sub-findings categorized as target, non-target and new lesions. Aggregated information for target lesions, such as the sum of the longest diameter (SLD) or the sum of the product of diameters (SPD) will be encoded in the target lesion container template.

Bottom Line: DICOM is the ubiquitous standard for the interchange of images for both clinical use as well as research.It also has capabilities for the exchange of image-related information, including categorical and quantitative information derived from images.The use of DICOM Structured Reporting for the encoding and interchange of clinical trial results in a standard manner is reviewed.

View Article: PubMed Central - PubMed

Affiliation: RadPharm, Princeton, NJ 08540, USA. dclunie@dclunie.com

ABSTRACT
The use of biomarkers derived from radiological images as surrogate end-points in therapeutic cancer clinical trials is well established. DICOM is the ubiquitous standard for the interchange of images for both clinical use as well as research. It also has capabilities for the exchange of image-related information, including categorical and quantitative information derived from images. The use of DICOM Structured Reporting for the encoding and interchange of clinical trial results in a standard manner is reviewed.

No MeSH data available.


Related in: MedlinePlus