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Treatment of recurrent mandibular myxoma by curettage and cryotherapy after thirty years.

Rocha AC, Gaujac C, Ceccheti MM, Amato-Filho G, Machado GG - Clinics (Sao Paulo) (2009)

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Large-sized lesions may cause tooth dislodgement and cortical bone expansion., Since pain and hypoesthesia are not common, the lesion may reach a considerable size before the patient perceives its existence and seeks treatment... No cortical bone or tooth root reabsorbtion were seen... Thus, the lesion did not penetrate the periosteum, and was not contiguous with the alveolar mucosa (Figure 4)... An incisional biopsy was made and a histopathological examination of the tissue sample exhibited rounded, spindled, and stellate cells arranged in a loose, myxoid stroma with few collagen fibrils... These results confirmed the clinical hypothesis of odontogenic myxoma (Figure 5)... The conservative treatment established for the case of recurrent mandibular myxoma reported in this paper was lesion excision with curettage and cryotherapy, which contrasts with the radical treatment of block resection that is advised by most authors. ,,,– This is due to the invasive nature, large size, and recurrence history of this lesion... The criterion used to make the decision between a radical treatment (block resection) and a conservative treatment (excision, curettage, and cryotherapy) involved the presence of the remaining basal mandibular bone, which provided a framework for mandibular re-structuring... Other authors advise resection with a safety margin for any case due to the high recurrence rate of these lesions... The conservative management of myxomas by lesion excision and curettage with liquid nitrogen cryotherapy is an alternative to radical block resection... Although complications due to bone freezing may occur, they do not compromise the success of the treatment... The proposed therapy enhances patient rehabilitation by maintaining a satisfactory facial contour, thereby significantly minimizing the psychosocial impact to the patient... In addition, this treatment represents a less expensive intervention compared to more radical procedures.

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Photomicrograph showing rounded, stellate and spindle-shaped mesenchymal cells arranged in abundant loose myxoid stroma with few collagen fibrils (hematoxylin-eosin, original magnification X100)
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f5-13-le-0022: Photomicrograph showing rounded, stellate and spindle-shaped mesenchymal cells arranged in abundant loose myxoid stroma with few collagen fibrils (hematoxylin-eosin, original magnification X100)

Mentions: An incisional biopsy was made and a histopathological examination of the tissue sample exhibited rounded, spindled, and stellate cells arranged in a loose, myxoid stroma with few collagen fibrils. These results confirmed the clinical hypothesis of odontogenic myxoma (Figure 5). Lesion excision was performed under general anesthesia, followed by vigorous curettage of the bone lodge and three 1 min liquid nitrogen sprayings with a defrosting interval between applications (Figure 6).


Treatment of recurrent mandibular myxoma by curettage and cryotherapy after thirty years.

Rocha AC, Gaujac C, Ceccheti MM, Amato-Filho G, Machado GG - Clinics (Sao Paulo) (2009)

Photomicrograph showing rounded, stellate and spindle-shaped mesenchymal cells arranged in abundant loose myxoid stroma with few collagen fibrils (hematoxylin-eosin, original magnification X100)
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2666483&req=5

f5-13-le-0022: Photomicrograph showing rounded, stellate and spindle-shaped mesenchymal cells arranged in abundant loose myxoid stroma with few collagen fibrils (hematoxylin-eosin, original magnification X100)
Mentions: An incisional biopsy was made and a histopathological examination of the tissue sample exhibited rounded, spindled, and stellate cells arranged in a loose, myxoid stroma with few collagen fibrils. These results confirmed the clinical hypothesis of odontogenic myxoma (Figure 5). Lesion excision was performed under general anesthesia, followed by vigorous curettage of the bone lodge and three 1 min liquid nitrogen sprayings with a defrosting interval between applications (Figure 6).

View Article: PubMed Central - PubMed

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Large-sized lesions may cause tooth dislodgement and cortical bone expansion., Since pain and hypoesthesia are not common, the lesion may reach a considerable size before the patient perceives its existence and seeks treatment... No cortical bone or tooth root reabsorbtion were seen... Thus, the lesion did not penetrate the periosteum, and was not contiguous with the alveolar mucosa (Figure 4)... An incisional biopsy was made and a histopathological examination of the tissue sample exhibited rounded, spindled, and stellate cells arranged in a loose, myxoid stroma with few collagen fibrils... These results confirmed the clinical hypothesis of odontogenic myxoma (Figure 5)... The conservative treatment established for the case of recurrent mandibular myxoma reported in this paper was lesion excision with curettage and cryotherapy, which contrasts with the radical treatment of block resection that is advised by most authors. ,,,– This is due to the invasive nature, large size, and recurrence history of this lesion... The criterion used to make the decision between a radical treatment (block resection) and a conservative treatment (excision, curettage, and cryotherapy) involved the presence of the remaining basal mandibular bone, which provided a framework for mandibular re-structuring... Other authors advise resection with a safety margin for any case due to the high recurrence rate of these lesions... The conservative management of myxomas by lesion excision and curettage with liquid nitrogen cryotherapy is an alternative to radical block resection... Although complications due to bone freezing may occur, they do not compromise the success of the treatment... The proposed therapy enhances patient rehabilitation by maintaining a satisfactory facial contour, thereby significantly minimizing the psychosocial impact to the patient... In addition, this treatment represents a less expensive intervention compared to more radical procedures.

Show MeSH