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Registry of Hospital das Clínicas of the University of São Paulo Medical School: first official solid organ and tissue transplantation report - 2008.

Azeka E, Auler Júnior JO, Fernandes PM, Nahas WC, Fiorelli AI, Tannuri U, Cristofani LM, Caiero MT, Dulley FL, Paggiaro Ade O, Bacchella T - Clinics (Sao Paulo) (2009)

Bottom Line: The aim of this study was to report a single center experience of organ and tissue transplantation This is the first report of organ and tissue transplantation at the Hospital das Clínicas of the University of Sao Paulo Medical School.We collected data from each type of organ transplantation from 2002 to 2007.This report shows that solid organ and tissue transplants are feasible within the institution and allow us to expect that the quality of transplantation will improve in the future.

View Article: PubMed Central - PubMed

Affiliation: Solid Organ and tissue Transplantation Committee, University of São Paulo Medical School, São Paulo/SP, Brazil. diretoria.clinica@hcnet.usp.br

ABSTRACT

Objective: The aim of this study was to report a single center experience of organ and tissue transplantation

Introduction: This is the first report of organ and tissue transplantation at the Hospital das Clínicas of the University of Sao Paulo Medical School.

Methods: We collected data from each type of organ transplantation from 2002 to 2007. The data collected were patient characteristics and actuarial survival Kaplan-Meier curves at 30 days, one year, and five years

Results: There were a total of 3,321 transplants at our institution and the 5-year survival curve ranged from 53% to 88%.

Conclusion: This report shows that solid organ and tissue transplants are feasible within the institution and allow us to expect that the quality of transplantation will improve in the future.

Show MeSH
Kaplan Meier survival curves - (2002 to 2007)
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f3-10-oa-0188: Kaplan Meier survival curves - (2002 to 2007)

Mentions: The immunosuppression used for induction therapy was methylprednisolone and thymoglobulin in all patients. The maintenance immunosuppression was the administration of calcineurin inhibitor in all patients, azathioprine in 4 patients (13%), and mychophenolate in 21 patients (65%). The major complications were 68 episodes of rejection (2.1 episodes per patient) and 61 episodes of infection (1.9 episodes per patient). No cases of tumor, diabetes mellitus, graft vascular disease, or renal failure (dialysis) were observed. Thirteen patients (40%) developed systemic arterial hypertension. Two re-transplantations were carried out. Nine (28%) patients died. The causes of mortality were rejection in five patients (55%), infection in three (33%), and multiple organ failure in one (11%) (Figure 2). The Kaplan-Meier curve was 80% at 30 days, 70% at 1 year, and 70% at 5 years (Figure 3).


Registry of Hospital das Clínicas of the University of São Paulo Medical School: first official solid organ and tissue transplantation report - 2008.

Azeka E, Auler Júnior JO, Fernandes PM, Nahas WC, Fiorelli AI, Tannuri U, Cristofani LM, Caiero MT, Dulley FL, Paggiaro Ade O, Bacchella T - Clinics (Sao Paulo) (2009)

Kaplan Meier survival curves - (2002 to 2007)
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2666479&req=5

f3-10-oa-0188: Kaplan Meier survival curves - (2002 to 2007)
Mentions: The immunosuppression used for induction therapy was methylprednisolone and thymoglobulin in all patients. The maintenance immunosuppression was the administration of calcineurin inhibitor in all patients, azathioprine in 4 patients (13%), and mychophenolate in 21 patients (65%). The major complications were 68 episodes of rejection (2.1 episodes per patient) and 61 episodes of infection (1.9 episodes per patient). No cases of tumor, diabetes mellitus, graft vascular disease, or renal failure (dialysis) were observed. Thirteen patients (40%) developed systemic arterial hypertension. Two re-transplantations were carried out. Nine (28%) patients died. The causes of mortality were rejection in five patients (55%), infection in three (33%), and multiple organ failure in one (11%) (Figure 2). The Kaplan-Meier curve was 80% at 30 days, 70% at 1 year, and 70% at 5 years (Figure 3).

Bottom Line: The aim of this study was to report a single center experience of organ and tissue transplantation This is the first report of organ and tissue transplantation at the Hospital das Clínicas of the University of Sao Paulo Medical School.We collected data from each type of organ transplantation from 2002 to 2007.This report shows that solid organ and tissue transplants are feasible within the institution and allow us to expect that the quality of transplantation will improve in the future.

View Article: PubMed Central - PubMed

Affiliation: Solid Organ and tissue Transplantation Committee, University of São Paulo Medical School, São Paulo/SP, Brazil. diretoria.clinica@hcnet.usp.br

ABSTRACT

Objective: The aim of this study was to report a single center experience of organ and tissue transplantation

Introduction: This is the first report of organ and tissue transplantation at the Hospital das Clínicas of the University of Sao Paulo Medical School.

Methods: We collected data from each type of organ transplantation from 2002 to 2007. The data collected were patient characteristics and actuarial survival Kaplan-Meier curves at 30 days, one year, and five years

Results: There were a total of 3,321 transplants at our institution and the 5-year survival curve ranged from 53% to 88%.

Conclusion: This report shows that solid organ and tissue transplants are feasible within the institution and allow us to expect that the quality of transplantation will improve in the future.

Show MeSH