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A brief review of chronic exercise intervention to prevent autonomic nervous system changes during the aging process.

Wichi RB, De Angelis K, Jones L, Irigoyen MC - Clinics (Sao Paulo) (2009)

Bottom Line: The aging process is associated with alterations in the cardiovascular and autonomic nervous systems.Chronic exercise in geriatrics seems to be associated with improvement in the cardiovascular system and seems to promote a healthy lifestyle.In this review, we address the major effects of aging on the autonomic nervous system in the context of cardiovascular control.

View Article: PubMed Central - PubMed

Affiliation: Human Movement Laboratory, Sao Judas Tadeu University - São Paulo/SP, Brazil. prof.rogeriowichi@usjt.br

ABSTRACT
The aging process is associated with alterations in the cardiovascular and autonomic nervous systems. Autonomic changes related to aging involve parasympathetic and sympathetic alterations leading to a higher incidence of cardiovascular disease morbidity and mortality. Several studies have suggested that physical exercise is effective in preventing deleterious changes. Chronic exercise in geriatrics seems to be associated with improvement in the cardiovascular system and seems to promote a healthy lifestyle. In this review, we address the major effects of aging on the autonomic nervous system in the context of cardiovascular control. We examine the use of chronic exercise to prevent cardiovascular changes during the aging process.

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Related in: MedlinePlus

A: Graphs showing no differences in sympathetic (ST) and vagal (VT) tone between young and old rats. The intrinsic HR (IHR) was lower in old rats. B: The increase in HR (from 347 ± 9 to 527 ± 11 beats/min) after methylatropine injection [vagal effect (VE)] was higher in young rates than in older specimens. * Significant difference between young and old rats (P< 0.05).
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f1-17-rv-0020: A: Graphs showing no differences in sympathetic (ST) and vagal (VT) tone between young and old rats. The intrinsic HR (IHR) was lower in old rats. B: The increase in HR (from 347 ± 9 to 527 ± 11 beats/min) after methylatropine injection [vagal effect (VE)] was higher in young rates than in older specimens. * Significant difference between young and old rats (P< 0.05).

Mentions: The impairment of cardiac-vagal neurons appears to be the major determinant of changes in the control of heart rate that come with aging, since aging reduces the tachycardia that may be induced by atropine in humans and animals.7 The study performed by our group demonstrated that the vagal effect as evaluated by methylatropine injection was greater in young rats than in old rats; young rats showed a lower intrinsic heart rate after methylatropine and propranolol blockade (Figure 1).8


A brief review of chronic exercise intervention to prevent autonomic nervous system changes during the aging process.

Wichi RB, De Angelis K, Jones L, Irigoyen MC - Clinics (Sao Paulo) (2009)

A: Graphs showing no differences in sympathetic (ST) and vagal (VT) tone between young and old rats. The intrinsic HR (IHR) was lower in old rats. B: The increase in HR (from 347 ± 9 to 527 ± 11 beats/min) after methylatropine injection [vagal effect (VE)] was higher in young rates than in older specimens. * Significant difference between young and old rats (P< 0.05).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2666449&req=5

f1-17-rv-0020: A: Graphs showing no differences in sympathetic (ST) and vagal (VT) tone between young and old rats. The intrinsic HR (IHR) was lower in old rats. B: The increase in HR (from 347 ± 9 to 527 ± 11 beats/min) after methylatropine injection [vagal effect (VE)] was higher in young rates than in older specimens. * Significant difference between young and old rats (P< 0.05).
Mentions: The impairment of cardiac-vagal neurons appears to be the major determinant of changes in the control of heart rate that come with aging, since aging reduces the tachycardia that may be induced by atropine in humans and animals.7 The study performed by our group demonstrated that the vagal effect as evaluated by methylatropine injection was greater in young rats than in old rats; young rats showed a lower intrinsic heart rate after methylatropine and propranolol blockade (Figure 1).8

Bottom Line: The aging process is associated with alterations in the cardiovascular and autonomic nervous systems.Chronic exercise in geriatrics seems to be associated with improvement in the cardiovascular system and seems to promote a healthy lifestyle.In this review, we address the major effects of aging on the autonomic nervous system in the context of cardiovascular control.

View Article: PubMed Central - PubMed

Affiliation: Human Movement Laboratory, Sao Judas Tadeu University - São Paulo/SP, Brazil. prof.rogeriowichi@usjt.br

ABSTRACT
The aging process is associated with alterations in the cardiovascular and autonomic nervous systems. Autonomic changes related to aging involve parasympathetic and sympathetic alterations leading to a higher incidence of cardiovascular disease morbidity and mortality. Several studies have suggested that physical exercise is effective in preventing deleterious changes. Chronic exercise in geriatrics seems to be associated with improvement in the cardiovascular system and seems to promote a healthy lifestyle. In this review, we address the major effects of aging on the autonomic nervous system in the context of cardiovascular control. We examine the use of chronic exercise to prevent cardiovascular changes during the aging process.

Show MeSH
Related in: MedlinePlus