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Model-based analysis of flow-mediated dilation and intima-media thickness.

Bartoli G, Menegaz G, Lisi M, Di Stolfo G, Dragoni S, Gori T - Int J Biomed Imaging (2009)

Bottom Line: The system allows real-time processing as well as a high level of interactivity with the user.This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time.Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

View Article: PubMed Central - PubMed

Affiliation: Department of Information Engineering, University of Siena, 53100 Siena, Italy.

ABSTRACT
We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data to detect the artery boundaries and track them all along the video sequence. The a priori knowledge about the image features and its content is exploited. Preprocessing is performed to improve both the visual quality of video frames for visual inspection and the performance of the segmentation algorithm without affecting the accuracy of the measurements. The system allows real-time processing as well as a high level of interactivity with the user. This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time. The system was validated and the accuracy, reproducibility, and repeatability of the measurements were assessed with extensive in vivo experiments. Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

No MeSH data available.


Related in: MedlinePlus

Reference frame: ROI selection.
© Copyright Policy - open-access
Related In: Results  -  Collection


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fig9: Reference frame: ROI selection.

Mentions: The system isequipped with a GUI that has been designed following the recommendations of thecardiologist of our team. It allows a high degree of interactivity at any timeduring the processing, which is a must when analyzing low-quality images andvideos. To initialize the procedure, the user is asked to click on twopositions close to the artery wall in a prototype frame used as reference, thathas been previously obtained by averaging all frames in the video. This allowsselecting an ideal crop area, where the image will remain stable and thearterial contours sharp throughout the FMD study (see Figure 9) in case the ROIoption are activated. A second window allows theoperator to click on two contiguous calibration marks in the image in order toset the number of pixels corresponding to a known distance (in [cm]), thusproviding quantitative measurement of the arterial diameter in metric units.


Model-based analysis of flow-mediated dilation and intima-media thickness.

Bartoli G, Menegaz G, Lisi M, Di Stolfo G, Dragoni S, Gori T - Int J Biomed Imaging (2009)

Reference frame: ROI selection.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2665907&req=5

fig9: Reference frame: ROI selection.
Mentions: The system isequipped with a GUI that has been designed following the recommendations of thecardiologist of our team. It allows a high degree of interactivity at any timeduring the processing, which is a must when analyzing low-quality images andvideos. To initialize the procedure, the user is asked to click on twopositions close to the artery wall in a prototype frame used as reference, thathas been previously obtained by averaging all frames in the video. This allowsselecting an ideal crop area, where the image will remain stable and thearterial contours sharp throughout the FMD study (see Figure 9) in case the ROIoption are activated. A second window allows theoperator to click on two contiguous calibration marks in the image in order toset the number of pixels corresponding to a known distance (in [cm]), thusproviding quantitative measurement of the arterial diameter in metric units.

Bottom Line: The system allows real-time processing as well as a high level of interactivity with the user.This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time.Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

View Article: PubMed Central - PubMed

Affiliation: Department of Information Engineering, University of Siena, 53100 Siena, Italy.

ABSTRACT
We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data to detect the artery boundaries and track them all along the video sequence. The a priori knowledge about the image features and its content is exploited. Preprocessing is performed to improve both the visual quality of video frames for visual inspection and the performance of the segmentation algorithm without affecting the accuracy of the measurements. The system allows real-time processing as well as a high level of interactivity with the user. This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time. The system was validated and the accuracy, reproducibility, and repeatability of the measurements were assessed with extensive in vivo experiments. Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

No MeSH data available.


Related in: MedlinePlus