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Model-based analysis of flow-mediated dilation and intima-media thickness.

Bartoli G, Menegaz G, Lisi M, Di Stolfo G, Dragoni S, Gori T - Int J Biomed Imaging (2009)

Bottom Line: The system allows real-time processing as well as a high level of interactivity with the user.This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time.Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

View Article: PubMed Central - PubMed

Affiliation: Department of Information Engineering, University of Siena, 53100 Siena, Italy.

ABSTRACT
We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data to detect the artery boundaries and track them all along the video sequence. The a priori knowledge about the image features and its content is exploited. Preprocessing is performed to improve both the visual quality of video frames for visual inspection and the performance of the segmentation algorithm without affecting the accuracy of the measurements. The system allows real-time processing as well as a high level of interactivity with the user. This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time. The system was validated and the accuracy, reproducibility, and repeatability of the measurements were assessed with extensive in vivo experiments. Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

No MeSH data available.


Related in: MedlinePlus

Correlation between repeated measurements in 25 healthy subjects studiedtwice with a delay of 24 hours. (a) Resting diameter; (b) FMD. The interclasscorrelation coefficients are ICC = 0.85 and ICC = 0.63, respectively.
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fig6: Correlation between repeated measurements in 25 healthy subjects studiedtwice with a delay of 24 hours. (a) Resting diameter; (b) FMD. The interclasscorrelation coefficients are ICC = 0.85 and ICC = 0.63, respectively.

Mentions: The intraclasscoefficient for diameter measurements repeated with a delay of 24 hours on thesame 25 subjects was ICC = 0.85 (Figure 6(a)). The intraclass correlation coefficient for repeated FMD measurements followingthe same paradigm was ICC = 0.63 (Figure 6(b)). The RV for each ofthese variables was 0.15 (0.01–0.40) mm for thediameter and 1.7 (0.1–5.2)% for FMD,respectively. CV was 4.5% for thediameter measurements.


Model-based analysis of flow-mediated dilation and intima-media thickness.

Bartoli G, Menegaz G, Lisi M, Di Stolfo G, Dragoni S, Gori T - Int J Biomed Imaging (2009)

Correlation between repeated measurements in 25 healthy subjects studiedtwice with a delay of 24 hours. (a) Resting diameter; (b) FMD. The interclasscorrelation coefficients are ICC = 0.85 and ICC = 0.63, respectively.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2665907&req=5

fig6: Correlation between repeated measurements in 25 healthy subjects studiedtwice with a delay of 24 hours. (a) Resting diameter; (b) FMD. The interclasscorrelation coefficients are ICC = 0.85 and ICC = 0.63, respectively.
Mentions: The intraclasscoefficient for diameter measurements repeated with a delay of 24 hours on thesame 25 subjects was ICC = 0.85 (Figure 6(a)). The intraclass correlation coefficient for repeated FMD measurements followingthe same paradigm was ICC = 0.63 (Figure 6(b)). The RV for each ofthese variables was 0.15 (0.01–0.40) mm for thediameter and 1.7 (0.1–5.2)% for FMD,respectively. CV was 4.5% for thediameter measurements.

Bottom Line: The system allows real-time processing as well as a high level of interactivity with the user.This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time.Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

View Article: PubMed Central - PubMed

Affiliation: Department of Information Engineering, University of Siena, 53100 Siena, Italy.

ABSTRACT
We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data to detect the artery boundaries and track them all along the video sequence. The a priori knowledge about the image features and its content is exploited. Preprocessing is performed to improve both the visual quality of video frames for visual inspection and the performance of the segmentation algorithm without affecting the accuracy of the measurements. The system allows real-time processing as well as a high level of interactivity with the user. This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time. The system was validated and the accuracy, reproducibility, and repeatability of the measurements were assessed with extensive in vivo experiments. Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

No MeSH data available.


Related in: MedlinePlus