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Model-based analysis of flow-mediated dilation and intima-media thickness.

Bartoli G, Menegaz G, Lisi M, Di Stolfo G, Dragoni S, Gori T - Int J Biomed Imaging (2009)

Bottom Line: The system allows real-time processing as well as a high level of interactivity with the user.This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time.Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

View Article: PubMed Central - PubMed

Affiliation: Department of Information Engineering, University of Siena, 53100 Siena, Italy.

ABSTRACT
We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data to detect the artery boundaries and track them all along the video sequence. The a priori knowledge about the image features and its content is exploited. Preprocessing is performed to improve both the visual quality of video frames for visual inspection and the performance of the segmentation algorithm without affecting the accuracy of the measurements. The system allows real-time processing as well as a high level of interactivity with the user. This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time. The system was validated and the accuracy, reproducibility, and repeatability of the measurements were assessed with extensive in vivo experiments. Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

No MeSH data available.


Related in: MedlinePlus

Preprocessing. (a) Original image; (b) after histogramstretching; (c) after sharpening.
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Related In: Results  -  Collection


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fig2: Preprocessing. (a) Original image; (b) after histogramstretching; (c) after sharpening.

Mentions: The effects of the preprocessing steps are illustratedin Figure 2. The original cropped image is shown in Figure 2(a), the effect ofcontrast enhancement through histogram stretching is illustrated in Figure2(b), and the final image after sharpening is shown in Figure 2(c). Asmentioned above, these steps support the subsequent contour extraction processas they enhance the contrast without compromising the accuracy of the targetmeasurement, as discussed above.


Model-based analysis of flow-mediated dilation and intima-media thickness.

Bartoli G, Menegaz G, Lisi M, Di Stolfo G, Dragoni S, Gori T - Int J Biomed Imaging (2009)

Preprocessing. (a) Original image; (b) after histogramstretching; (c) after sharpening.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2665907&req=5

fig2: Preprocessing. (a) Original image; (b) after histogramstretching; (c) after sharpening.
Mentions: The effects of the preprocessing steps are illustratedin Figure 2. The original cropped image is shown in Figure 2(a), the effect ofcontrast enhancement through histogram stretching is illustrated in Figure2(b), and the final image after sharpening is shown in Figure 2(c). Asmentioned above, these steps support the subsequent contour extraction processas they enhance the contrast without compromising the accuracy of the targetmeasurement, as discussed above.

Bottom Line: The system allows real-time processing as well as a high level of interactivity with the user.This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time.Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

View Article: PubMed Central - PubMed

Affiliation: Department of Information Engineering, University of Siena, 53100 Siena, Italy.

ABSTRACT
We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data to detect the artery boundaries and track them all along the video sequence. The a priori knowledge about the image features and its content is exploited. Preprocessing is performed to improve both the visual quality of video frames for visual inspection and the performance of the segmentation algorithm without affecting the accuracy of the measurements. The system allows real-time processing as well as a high level of interactivity with the user. This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time. The system was validated and the accuracy, reproducibility, and repeatability of the measurements were assessed with extensive in vivo experiments. Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.

No MeSH data available.


Related in: MedlinePlus