Mentions: Galaxie's SmartTimeUpdate is a novel approach applicable toboth gas chromatography (GC) and liquid chromatography (HPLC), which usestraditional reference peaks to automatically correct both retention times andpeak processing timed events without any need to alter instruments' parameters.When reference peak times have shifted, both the timed events' table and thepeak detection table are automatically modified resulting in peak processingparameters that can accurately process the new chromatograms. In Figure 8, when thechromatogram retention times have shifted, the original times for events areincorrect and the corrected times produce proper peak processing. Systematicchanges in retention times can be tracked as systematic alterations in peakprocessing events. If normal retention time variations are of the same order ofmagnitude as the systematic changes, SmartTimeUpdates can be scaled to shiftpeak times and timed events a fraction of the measured change, thereforepreventing overcompensation of the time shift.
Affiliation: P S Analytical, Arthur House, Crayfields Industrial Estate, Main Road, Orpington, Kent BR5 3Hp, UK.
No MeSH data available.