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Abstracts of papers presented at the 2008 pittsburgh conference.

Stockwell PB - J Autom Methods Manag Chem (2009)

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Affiliation: P S Analytical, Arthur House, Crayfields Industrial Estate, Main Road, Orpington, Kent BR5 3Hp, UK.

No MeSH data available.


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Related In: Results  -  Collection


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Mentions: We have recently implemented surface-induceddissociation (SID) within a Q-TOF mass spectrometer for the study of proteinassemblies. The sudden activation provided by SID results in a more symmetricproduct ion distribution and fragments other than monomer and (n-1)-mer,indicating that SID may yield additional information about the organization ofsubunits within a complex. Results are presented for SID of bacteriophage Croproteins, bovine insulin oligomers, and heat shock proteins from severalorganisms. These complexes demonstrate how the surface-induced dissociation ofprotein assemblies is affected by their molecular weight, subunit number,interfacial contact area, and subunit conformation (see Figure 4).


Abstracts of papers presented at the 2008 pittsburgh conference.

Stockwell PB - J Autom Methods Manag Chem (2009)

© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2665694&req=5

Mentions: We have recently implemented surface-induceddissociation (SID) within a Q-TOF mass spectrometer for the study of proteinassemblies. The sudden activation provided by SID results in a more symmetricproduct ion distribution and fragments other than monomer and (n-1)-mer,indicating that SID may yield additional information about the organization ofsubunits within a complex. Results are presented for SID of bacteriophage Croproteins, bovine insulin oligomers, and heat shock proteins from severalorganisms. These complexes demonstrate how the surface-induced dissociation ofprotein assemblies is affected by their molecular weight, subunit number,interfacial contact area, and subunit conformation (see Figure 4).

View Article: PubMed Central - PubMed

Affiliation: P S Analytical, Arthur House, Crayfields Industrial Estate, Main Road, Orpington, Kent BR5 3Hp, UK.

No MeSH data available.