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A new dawn for the use of traditional Chinese medicine in cancer therapy.

Parekh HS, Liu G, Wei MQ - Mol. Cancer (2009)

Bottom Line: Although traditional Chinese medicine has benefitted one fifth of the world's population in treating a plethora of diseases, its acceptance as a real therapeutic option by the West is only now emerging.In light of a new wave of recognition being given to traditional Chinese medicine by health professionals and regulatory bodies in the West, an understanding of their molecular basis and highlighting potential future applications of a proven group of traditional Chinese medicine in the treatment of a variety of cancers is crucial - this is where their calling holds much hope and promise in both animal and human trials.Furthermore, the rationale for combining conventional agents and modern biotechnological approaches to the delivery of traditional Chinese medicine is an avenue set to revolutionize the future practice of cancer medicine - and this may well bring on a new dawn of therapeutic strategies where East truly meets West.

View Article: PubMed Central - HTML - PubMed

Affiliation: The University of Queensland, School of Pharmacy, Brisbane, Australia. h.parekh@pharmacy.uq.edu.au

ABSTRACT
Although traditional Chinese medicine has benefitted one fifth of the world's population in treating a plethora of diseases, its acceptance as a real therapeutic option by the West is only now emerging. In light of a new wave of recognition being given to traditional Chinese medicine by health professionals and regulatory bodies in the West, an understanding of their molecular basis and highlighting potential future applications of a proven group of traditional Chinese medicine in the treatment of a variety of cancers is crucial - this is where their calling holds much hope and promise in both animal and human trials. Furthermore, the rationale for combining conventional agents and modern biotechnological approaches to the delivery of traditional Chinese medicine is an avenue set to revolutionize the future practice of cancer medicine - and this may well bring on a new dawn of therapeutic strategies where East truly meets West.

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The complex interplay between the primary mechanisms of TCM.
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Related In: Results  -  Collection

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Figure 1: The complex interplay between the primary mechanisms of TCM.

Mentions: The age-old holistic approach employed by Chinese practitioners proposes that a multitude of events are key to returning a patient to a healthy state; where cancer therapy is concerned these primarily include an interplay between the induction of apoptosis/cell-cycle arrest, inhibition of angiogenesis, overcoming multidrug resistance (MDR), and boosting the immune system (Figure 1). Following an extensive review of the literature we describe the detailed molecular basis of a proven group of TCM, and highlight reported synergies when administered alongside so-called 'conventional therapies' in tumour cell regulation and in bringing about homeostasis.


A new dawn for the use of traditional Chinese medicine in cancer therapy.

Parekh HS, Liu G, Wei MQ - Mol. Cancer (2009)

The complex interplay between the primary mechanisms of TCM.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2664781&req=5

Figure 1: The complex interplay between the primary mechanisms of TCM.
Mentions: The age-old holistic approach employed by Chinese practitioners proposes that a multitude of events are key to returning a patient to a healthy state; where cancer therapy is concerned these primarily include an interplay between the induction of apoptosis/cell-cycle arrest, inhibition of angiogenesis, overcoming multidrug resistance (MDR), and boosting the immune system (Figure 1). Following an extensive review of the literature we describe the detailed molecular basis of a proven group of TCM, and highlight reported synergies when administered alongside so-called 'conventional therapies' in tumour cell regulation and in bringing about homeostasis.

Bottom Line: Although traditional Chinese medicine has benefitted one fifth of the world's population in treating a plethora of diseases, its acceptance as a real therapeutic option by the West is only now emerging.In light of a new wave of recognition being given to traditional Chinese medicine by health professionals and regulatory bodies in the West, an understanding of their molecular basis and highlighting potential future applications of a proven group of traditional Chinese medicine in the treatment of a variety of cancers is crucial - this is where their calling holds much hope and promise in both animal and human trials.Furthermore, the rationale for combining conventional agents and modern biotechnological approaches to the delivery of traditional Chinese medicine is an avenue set to revolutionize the future practice of cancer medicine - and this may well bring on a new dawn of therapeutic strategies where East truly meets West.

View Article: PubMed Central - HTML - PubMed

Affiliation: The University of Queensland, School of Pharmacy, Brisbane, Australia. h.parekh@pharmacy.uq.edu.au

ABSTRACT
Although traditional Chinese medicine has benefitted one fifth of the world's population in treating a plethora of diseases, its acceptance as a real therapeutic option by the West is only now emerging. In light of a new wave of recognition being given to traditional Chinese medicine by health professionals and regulatory bodies in the West, an understanding of their molecular basis and highlighting potential future applications of a proven group of traditional Chinese medicine in the treatment of a variety of cancers is crucial - this is where their calling holds much hope and promise in both animal and human trials. Furthermore, the rationale for combining conventional agents and modern biotechnological approaches to the delivery of traditional Chinese medicine is an avenue set to revolutionize the future practice of cancer medicine - and this may well bring on a new dawn of therapeutic strategies where East truly meets West.

Show MeSH
Related in: MedlinePlus