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Is brain banking of psychiatric cases valuable for neurobiological research?

Schmitt A, Parlapani E, Bauer M, Heinsen H, Falkai P - Clinics (Sao Paulo) (2008)

Bottom Line: It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders.The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders.Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychiatry, University of Goettingen, Germany. aschmit@gwdg.de

ABSTRACT
It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized.

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Related in: MedlinePlus

Dissection of the thalamus (mediodorsal nucleus).
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f2-cln63_2p0255: Dissection of the thalamus (mediodorsal nucleus).


Is brain banking of psychiatric cases valuable for neurobiological research?

Schmitt A, Parlapani E, Bauer M, Heinsen H, Falkai P - Clinics (Sao Paulo) (2008)

Dissection of the thalamus (mediodorsal nucleus).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2664212&req=5

f2-cln63_2p0255: Dissection of the thalamus (mediodorsal nucleus).
Bottom Line: It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders.The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders.Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychiatry, University of Goettingen, Germany. aschmit@gwdg.de

ABSTRACT
It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized.

Show MeSH
Related in: MedlinePlus