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One-year follow-up of patients with first-episode schizophrenia (comparison between remitters and non-remitters).

Cesková E, Radovan P, Tomás K, Hana K - Neuropsychiatr Dis Treat (2007)

Bottom Line: No statistically significant differences in the total PANSS or subscales scores were found between remitters and non-remitters before or after the first episode treatment.However, non-remitters had a significantly higher total PANSS score after 1 year than remitters.However, significantly higher mean values were found for all items after 1 year in non-remitters than remitters.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychiatry, Masaryk University and Faculty Hospital Brno, Czech Republic. eceska@med.muni.cz

ABSTRACT
Patients admitted to hospital after being diagnosed with first-episode schizophrenia were comprehensively assessed prior to acute treatment (on admission), at the end of the acute treatment (at discharge), and at follow-up after 1 year. The psychopathology was evaluated using the Positive and Negative Syndrome Scale (PANSS). 93 patients were reassessed after 1 year. 73/93 (78%) of the patients fulfilled the criteria for remission. No statistically significant differences in the total PANSS or subscales scores were found between remitters and non-remitters before or after the first episode treatment. However, non-remitters had a significantly higher total PANSS score after 1 year than remitters. There was no significant difference in mean psychopathology on admission or at discharge, with the exception of items conceptual disorganization, difficulty in abstract thinking, and lack of judgment and insight between remitters and non-remitters. However, significantly higher mean values were found for all items after 1 year in non-remitters than remitters. On admission the occurrence of positive, negative and general symptoms was balanced; at discharge and after 1 year negative and general symptoms were the most frequently observed. At the 1-year follow-up the impairment of insight and judgment is one of the most frequent symptoms in both remitters (10%) and non-remitters (70%).

No MeSH data available.


Related in: MedlinePlus

Psychopathology: comparison between remitters and non-remitters.*Note: significant difference between remitters and non-remitters (p < 0.001).
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f1-ndt-3-153: Psychopathology: comparison between remitters and non-remitters.*Note: significant difference between remitters and non-remitters (p < 0.001).

Mentions: No statistically significant differences in the total PANSS or subscales scores were found between remitters and non-remitters before or after the first episode treatment. However, non-remitters had a significantly higher total PANSS score after 1 year than remitters (p < 0.001) (Figure 1, Table 1).


One-year follow-up of patients with first-episode schizophrenia (comparison between remitters and non-remitters).

Cesková E, Radovan P, Tomás K, Hana K - Neuropsychiatr Dis Treat (2007)

Psychopathology: comparison between remitters and non-remitters.*Note: significant difference between remitters and non-remitters (p < 0.001).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2654532&req=5

f1-ndt-3-153: Psychopathology: comparison between remitters and non-remitters.*Note: significant difference between remitters and non-remitters (p < 0.001).
Mentions: No statistically significant differences in the total PANSS or subscales scores were found between remitters and non-remitters before or after the first episode treatment. However, non-remitters had a significantly higher total PANSS score after 1 year than remitters (p < 0.001) (Figure 1, Table 1).

Bottom Line: No statistically significant differences in the total PANSS or subscales scores were found between remitters and non-remitters before or after the first episode treatment.However, non-remitters had a significantly higher total PANSS score after 1 year than remitters.However, significantly higher mean values were found for all items after 1 year in non-remitters than remitters.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychiatry, Masaryk University and Faculty Hospital Brno, Czech Republic. eceska@med.muni.cz

ABSTRACT
Patients admitted to hospital after being diagnosed with first-episode schizophrenia were comprehensively assessed prior to acute treatment (on admission), at the end of the acute treatment (at discharge), and at follow-up after 1 year. The psychopathology was evaluated using the Positive and Negative Syndrome Scale (PANSS). 93 patients were reassessed after 1 year. 73/93 (78%) of the patients fulfilled the criteria for remission. No statistically significant differences in the total PANSS or subscales scores were found between remitters and non-remitters before or after the first episode treatment. However, non-remitters had a significantly higher total PANSS score after 1 year than remitters. There was no significant difference in mean psychopathology on admission or at discharge, with the exception of items conceptual disorganization, difficulty in abstract thinking, and lack of judgment and insight between remitters and non-remitters. However, significantly higher mean values were found for all items after 1 year in non-remitters than remitters. On admission the occurrence of positive, negative and general symptoms was balanced; at discharge and after 1 year negative and general symptoms were the most frequently observed. At the 1-year follow-up the impairment of insight and judgment is one of the most frequent symptoms in both remitters (10%) and non-remitters (70%).

No MeSH data available.


Related in: MedlinePlus