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The psychosocial screen for cancer (PSSCAN): further validation and normative data.

Linden W, Andrea Vodermaier A, McKenzie R, Barroetavena MC, Yi D, Doll R - Health Qual Life Outcomes (2009)

Bottom Line: Needed were additional analyses to recommend empirically justified cut-off scores as well as data norms for healthy adult samples so as to lend meaning to the recommended cut-off scores.Sensitivity/specificity analyses revealed that an excellent balance of sensitivity/specificity was achievable with 92%/98% respectively for clinical anxiety and 100% and 86% respectively for clinical depression.These additional data on criterion validity and community versus patient norms for PSSCAN serve to enhance its utility for clinical practice.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Psychology, University of British Columbia, Vancouver, BC, Canada. wlinden@psych.ubc.ca

ABSTRACT

Background: We have previously reported on the development of a cancer-specific screening instrument for anxiety and depression (PSSCAN). No information on cut-off scores or their meaning for diagnosis was available when PSSCAN was first described. Needed were additional analyses to recommend empirically justified cut-off scores as well as data norms for healthy adult samples so as to lend meaning to the recommended cut-off scores.

Methods: We computed sensitivity/specificity indices based on a sample of 101 cancer patients who had provided PSSCAN data on anxiety and depression and who had completed another standardized instrument with strong psychometrics. Next, we compared mean scores for four samples with known differences in health status, a healthy community sample (n = 561), a sample of patients with a representative mix of cancer subtypes (n = 570), a more severely ill sample of in-patients with cancer (n = 78), and a community sample with a chronic illness other than cancer (n = 85).

Results: Sensitivity/specificity analyses revealed that an excellent balance of sensitivity/specificity was achievable with 92%/98% respectively for clinical anxiety and 100% and 86% respectively for clinical depression. Newly diagnosed patients with cancer were no more anxious than healthy community controls but showed elevations in depression scores. Both, patients with chronic illness other than cancer and those with longer-standing cancer diagnoses revealed greater levels of distress than newly diagnosed cancer patients or healthy adult controls.

Conclusion: These additional data on criterion validity and community versus patient norms for PSSCAN serve to enhance its utility for clinical practice.

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Related in: MedlinePlus

a and b. Receiver Operating Curves for the Anxiety Subscale of the PSSCAN with the Anxiety Subscale of the HADS as the Criterion; Fig a: subclinical threshold; Fig b clinical threshold.
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Figure 1: a and b. Receiver Operating Curves for the Anxiety Subscale of the PSSCAN with the Anxiety Subscale of the HADS as the Criterion; Fig a: subclinical threshold; Fig b clinical threshold.

Mentions: Complete data were available from 101 cancer patients with a mean age of 53 years, composed of 60 women and 41 men. ROC curves are displayed in Figures 1a and 1b, and Figures 2a and 2b; sensitivity/specificity data are shown in Table 1.


The psychosocial screen for cancer (PSSCAN): further validation and normative data.

Linden W, Andrea Vodermaier A, McKenzie R, Barroetavena MC, Yi D, Doll R - Health Qual Life Outcomes (2009)

a and b. Receiver Operating Curves for the Anxiety Subscale of the PSSCAN with the Anxiety Subscale of the HADS as the Criterion; Fig a: subclinical threshold; Fig b clinical threshold.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2651864&req=5

Figure 1: a and b. Receiver Operating Curves for the Anxiety Subscale of the PSSCAN with the Anxiety Subscale of the HADS as the Criterion; Fig a: subclinical threshold; Fig b clinical threshold.
Mentions: Complete data were available from 101 cancer patients with a mean age of 53 years, composed of 60 women and 41 men. ROC curves are displayed in Figures 1a and 1b, and Figures 2a and 2b; sensitivity/specificity data are shown in Table 1.

Bottom Line: Needed were additional analyses to recommend empirically justified cut-off scores as well as data norms for healthy adult samples so as to lend meaning to the recommended cut-off scores.Sensitivity/specificity analyses revealed that an excellent balance of sensitivity/specificity was achievable with 92%/98% respectively for clinical anxiety and 100% and 86% respectively for clinical depression.These additional data on criterion validity and community versus patient norms for PSSCAN serve to enhance its utility for clinical practice.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Psychology, University of British Columbia, Vancouver, BC, Canada. wlinden@psych.ubc.ca

ABSTRACT

Background: We have previously reported on the development of a cancer-specific screening instrument for anxiety and depression (PSSCAN). No information on cut-off scores or their meaning for diagnosis was available when PSSCAN was first described. Needed were additional analyses to recommend empirically justified cut-off scores as well as data norms for healthy adult samples so as to lend meaning to the recommended cut-off scores.

Methods: We computed sensitivity/specificity indices based on a sample of 101 cancer patients who had provided PSSCAN data on anxiety and depression and who had completed another standardized instrument with strong psychometrics. Next, we compared mean scores for four samples with known differences in health status, a healthy community sample (n = 561), a sample of patients with a representative mix of cancer subtypes (n = 570), a more severely ill sample of in-patients with cancer (n = 78), and a community sample with a chronic illness other than cancer (n = 85).

Results: Sensitivity/specificity analyses revealed that an excellent balance of sensitivity/specificity was achievable with 92%/98% respectively for clinical anxiety and 100% and 86% respectively for clinical depression. Newly diagnosed patients with cancer were no more anxious than healthy community controls but showed elevations in depression scores. Both, patients with chronic illness other than cancer and those with longer-standing cancer diagnoses revealed greater levels of distress than newly diagnosed cancer patients or healthy adult controls.

Conclusion: These additional data on criterion validity and community versus patient norms for PSSCAN serve to enhance its utility for clinical practice.

Show MeSH
Related in: MedlinePlus