Limits...
Imaging of the unusual pediatric 'blastomas'.

Papaioannou G, Sebire NJ, McHugh K - Cancer Imaging (2009)

Bottom Line: We present examples of the more unusual blastematous pediatric tumors (lipoblastoma, osteoblastoma, chondroblastoma, hemangioblastoma, gonadoblastoma, sialoblastoma, pleuropulmonary blastoma, pancreatoblastoma, pineoblastoma, and medullomyoblastoma) that were recorded in our institution.Imaging is often non-specific but plays an important role in their identification, management and follow-up.Some characteristic imaging features at diagnosis, encountered in cases diagnosed and treated in our institution, are described and reviewed.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Great Ormond Street Hospital, Great Ormond Street, London, WC1N 3JH, UK. gpapaio@hotmail.com

ABSTRACT
'Blastomas' are tumors virtually unique to childhood. Controversy surrounds their nomenclature and there is no globally accepted classification. They are thought to arise from immature, primitive tissues that present persistent embryonal elements on histology, affect a younger pediatric population and are usually malignant. The 'commoner' blastomas (neuroblastoma, nephroblastoma, hepatoblastoma, medulloblastoma) account for approximately 25% of solid tumors in the pediatric age range. We present examples of the more unusual blastematous pediatric tumors (lipoblastoma, osteoblastoma, chondroblastoma, hemangioblastoma, gonadoblastoma, sialoblastoma, pleuropulmonary blastoma, pancreatoblastoma, pineoblastoma, and medullomyoblastoma) that were recorded in our institution. Although these rare types of blastomas individually account for <1% of pediatric malignancies, collectively they may be responsible for up to 5% of pediatric tumors in a given population of young children. Imaging is often non-specific but plays an important role in their identification, management and follow-up. Some characteristic imaging features at diagnosis, encountered in cases diagnosed and treated in our institution, are described and reviewed.

Show MeSH

Related in: MedlinePlus

A 10-year-old girl with an abdominal mass due to gonadoblastoma. CT of the abdomen post injection of contrast showed a large heterogeneous soft-tissue mass which occupied the pelvis and displaced the uterus posteriorly (arrow). A small amount of fluid is noted behind the uterus.
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC2651735&req=5

Figure 7: A 10-year-old girl with an abdominal mass due to gonadoblastoma. CT of the abdomen post injection of contrast showed a large heterogeneous soft-tissue mass which occupied the pelvis and displaced the uterus posteriorly (arrow). A small amount of fluid is noted behind the uterus.

Mentions: Gonadoblastomas may represent microscopic neoplasms, too small to be detected by diagnostic imaging. When obvious macroscopically, ovaries with gonadoblastoma development have the appearance of solid tumors in the lower abdomen on US and CT while some cases with bloody ascites have been reported[29] (Fig. 7). Testicular gonadoblastoma on US presents as a hyperechoic area in the central part of the affected testicle[30].


Imaging of the unusual pediatric 'blastomas'.

Papaioannou G, Sebire NJ, McHugh K - Cancer Imaging (2009)

A 10-year-old girl with an abdominal mass due to gonadoblastoma. CT of the abdomen post injection of contrast showed a large heterogeneous soft-tissue mass which occupied the pelvis and displaced the uterus posteriorly (arrow). A small amount of fluid is noted behind the uterus.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2651735&req=5

Figure 7: A 10-year-old girl with an abdominal mass due to gonadoblastoma. CT of the abdomen post injection of contrast showed a large heterogeneous soft-tissue mass which occupied the pelvis and displaced the uterus posteriorly (arrow). A small amount of fluid is noted behind the uterus.
Mentions: Gonadoblastomas may represent microscopic neoplasms, too small to be detected by diagnostic imaging. When obvious macroscopically, ovaries with gonadoblastoma development have the appearance of solid tumors in the lower abdomen on US and CT while some cases with bloody ascites have been reported[29] (Fig. 7). Testicular gonadoblastoma on US presents as a hyperechoic area in the central part of the affected testicle[30].

Bottom Line: We present examples of the more unusual blastematous pediatric tumors (lipoblastoma, osteoblastoma, chondroblastoma, hemangioblastoma, gonadoblastoma, sialoblastoma, pleuropulmonary blastoma, pancreatoblastoma, pineoblastoma, and medullomyoblastoma) that were recorded in our institution.Imaging is often non-specific but plays an important role in their identification, management and follow-up.Some characteristic imaging features at diagnosis, encountered in cases diagnosed and treated in our institution, are described and reviewed.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Great Ormond Street Hospital, Great Ormond Street, London, WC1N 3JH, UK. gpapaio@hotmail.com

ABSTRACT
'Blastomas' are tumors virtually unique to childhood. Controversy surrounds their nomenclature and there is no globally accepted classification. They are thought to arise from immature, primitive tissues that present persistent embryonal elements on histology, affect a younger pediatric population and are usually malignant. The 'commoner' blastomas (neuroblastoma, nephroblastoma, hepatoblastoma, medulloblastoma) account for approximately 25% of solid tumors in the pediatric age range. We present examples of the more unusual blastematous pediatric tumors (lipoblastoma, osteoblastoma, chondroblastoma, hemangioblastoma, gonadoblastoma, sialoblastoma, pleuropulmonary blastoma, pancreatoblastoma, pineoblastoma, and medullomyoblastoma) that were recorded in our institution. Although these rare types of blastomas individually account for <1% of pediatric malignancies, collectively they may be responsible for up to 5% of pediatric tumors in a given population of young children. Imaging is often non-specific but plays an important role in their identification, management and follow-up. Some characteristic imaging features at diagnosis, encountered in cases diagnosed and treated in our institution, are described and reviewed.

Show MeSH
Related in: MedlinePlus