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Identification of potential environmentally adapted Campylobacter jejuni strain, United Kingdom.

Sopwith W, Birtles A, Matthews M, Fox A, Gee S, Painter M, Regan M, Syed Q, Bolton E - Emerging Infect. Dis. (2008)

Bottom Line: In a study of Campylobacter infection in northwestern England, 2003-2006, C. jejuni multilocus sequence type (ST)-45 was associated with early summer onset and was the most prevalent C. jejuni type in surface waters.ST-45 is likely more adapted to survival outside a host, making it a key driver of transmission between livestock, environmental, and human settings.

View Article: PubMed Central - PubMed

Affiliation: Health Protection Agency, North West, Liverpool, UK. will.sopwith@hpa.org.uk

ABSTRACT
In a study of Campylobacter infection in northwestern England, 2003-2006, C. jejuni multilocus sequence type (ST)-45 was associated with early summer onset and was the most prevalent C. jejuni type in surface waters. ST-45 is likely more adapted to survival outside a host, making it a key driver of transmission between livestock, environmental, and human settings.

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Related in: MedlinePlus

Stacked area charts showing the number of human case reports of the 4 most prevalent sequence types (STs) during the study, by 4-week intervals.
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Figure 1: Stacked area charts showing the number of human case reports of the 4 most prevalent sequence types (STs) during the study, by 4-week intervals.

Mentions: Among the typed isolates of C. jejuni (n = 1,104), ST-45 (n = 49) was the third most prevalent sequence type reported in the study (after ST-257 and ST-21) and highly restricted to cases reported between late April (week 17) and early August (week 32) (Figure 1). When week of diagnosis was categorized into 2 seasons (early summer [weeks 17–28] and all other weeks), logistic regression of season by sequence type confirmed that, when compared with all other typed cases of C. jejuni, cases of ST-45 were more likely to be reported in early summer than during the rest of the year (odds ratio 2.79, confidence interval 1.56–4.99, p = 0.001; 1,008 observations), and this relationship was not seen with other prevalent sequence types.


Identification of potential environmentally adapted Campylobacter jejuni strain, United Kingdom.

Sopwith W, Birtles A, Matthews M, Fox A, Gee S, Painter M, Regan M, Syed Q, Bolton E - Emerging Infect. Dis. (2008)

Stacked area charts showing the number of human case reports of the 4 most prevalent sequence types (STs) during the study, by 4-week intervals.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2630731&req=5

Figure 1: Stacked area charts showing the number of human case reports of the 4 most prevalent sequence types (STs) during the study, by 4-week intervals.
Mentions: Among the typed isolates of C. jejuni (n = 1,104), ST-45 (n = 49) was the third most prevalent sequence type reported in the study (after ST-257 and ST-21) and highly restricted to cases reported between late April (week 17) and early August (week 32) (Figure 1). When week of diagnosis was categorized into 2 seasons (early summer [weeks 17–28] and all other weeks), logistic regression of season by sequence type confirmed that, when compared with all other typed cases of C. jejuni, cases of ST-45 were more likely to be reported in early summer than during the rest of the year (odds ratio 2.79, confidence interval 1.56–4.99, p = 0.001; 1,008 observations), and this relationship was not seen with other prevalent sequence types.

Bottom Line: In a study of Campylobacter infection in northwestern England, 2003-2006, C. jejuni multilocus sequence type (ST)-45 was associated with early summer onset and was the most prevalent C. jejuni type in surface waters.ST-45 is likely more adapted to survival outside a host, making it a key driver of transmission between livestock, environmental, and human settings.

View Article: PubMed Central - PubMed

Affiliation: Health Protection Agency, North West, Liverpool, UK. will.sopwith@hpa.org.uk

ABSTRACT
In a study of Campylobacter infection in northwestern England, 2003-2006, C. jejuni multilocus sequence type (ST)-45 was associated with early summer onset and was the most prevalent C. jejuni type in surface waters. ST-45 is likely more adapted to survival outside a host, making it a key driver of transmission between livestock, environmental, and human settings.

Show MeSH
Related in: MedlinePlus