Limits...
Validation of a novel device to objectively measure adherence to long-term oxygen therapy.

Lin SK, Bogen DK, Kuna ST - Int J Chron Obstruct Pulmon Dis (2008)

Bottom Line: The monitor's measurements were obtained at 4-minute intervals and compared to actual oxygen use determined by review of time-synchronized video recordings.All errors were false negatives, ie, the monitor failed to detect that the participant was actually wearing the cannula.Application of a majority-vote filter to the raw data improved overall detection accuracy to 84.9%.

View Article: PubMed Central - PubMed

Affiliation: Department of Bioengineering, University of Pennsylvania, Philadelphia 19104, USA.

ABSTRACT

Rationale: We have developed a novel oxygen adherence monitor that objectively measures patient use of long-term oxygen therapy. The monitor attaches to the oxygen source and detects whether or not the patient is wearing the nasal cannula.

Objective: The study's purpose was to validate the monitor's performance in patients with chronic obstructive pulmonary disease during wakefulness and sleep.

Methods: Ten adult males with stable chronic obstructive pulmonary disease (mean +/- SD FEV1 37.7 +/- 14.9% of predicted) on long-term continuous oxygen therapy were tested in a sleep laboratory over a 12-13 hour period that included an overnight polysomnogram.

Measurements: The monitor's measurements were obtained at 4-minute intervals and compared to actual oxygen use determined by review of time-synchronized video recordings.

Main results: The monitor made 1504/1888 (79.7%) correct detections (unprocessed data) across all participants: 957/1,118 (85.6%) correct detections during wakefulness and 546/770 (70.9%) during sleep. All errors were false negatives, ie, the monitor failed to detect that the participant was actually wearing the cannula. Application of a majority-vote filter to the raw data improved overall detection accuracy to 84.9%.

Conclusions: The results demonstrate the monitor's ability to objectively measure whether or not men with chronic obstructive pulmonary disease are receiving their oxygen treatment. The ability to objectively measure oxygen delivery, rather than oxygen expended, may help improve the management of patients on long-term oxygen therapy.

Show MeSH

Related in: MedlinePlus

Percent of correct measurements with the oxygen adherence monitor versus apnea-hypopnea index (AHI) during sleep in all ten participants. The square markers represent the two participants in whom there were a high number of incorrect measurements despite a relatively low AHI. Regression lines are shown for data including all participants (solid line, R2 = 0.083) and data excluding two of the subjects (dashed line, excluding square markers, R2 = 0.93, p < 0.001).
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC2629983&req=5

f1-copd-3-435: Percent of correct measurements with the oxygen adherence monitor versus apnea-hypopnea index (AHI) during sleep in all ten participants. The square markers represent the two participants in whom there were a high number of incorrect measurements despite a relatively low AHI. Regression lines are shown for data including all participants (solid line, R2 = 0.083) and data excluding two of the subjects (dashed line, excluding square markers, R2 = 0.93, p < 0.001).

Mentions: There were no findings on routine history or physical exam that identified those individuals in whom there was lower detection accuracy during wakefulness. Figure 1 shows the relationship between the percentage of correct measurements during sleep and the apnea-hypopnea index in all participants.


Validation of a novel device to objectively measure adherence to long-term oxygen therapy.

Lin SK, Bogen DK, Kuna ST - Int J Chron Obstruct Pulmon Dis (2008)

Percent of correct measurements with the oxygen adherence monitor versus apnea-hypopnea index (AHI) during sleep in all ten participants. The square markers represent the two participants in whom there were a high number of incorrect measurements despite a relatively low AHI. Regression lines are shown for data including all participants (solid line, R2 = 0.083) and data excluding two of the subjects (dashed line, excluding square markers, R2 = 0.93, p < 0.001).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2629983&req=5

f1-copd-3-435: Percent of correct measurements with the oxygen adherence monitor versus apnea-hypopnea index (AHI) during sleep in all ten participants. The square markers represent the two participants in whom there were a high number of incorrect measurements despite a relatively low AHI. Regression lines are shown for data including all participants (solid line, R2 = 0.083) and data excluding two of the subjects (dashed line, excluding square markers, R2 = 0.93, p < 0.001).
Mentions: There were no findings on routine history or physical exam that identified those individuals in whom there was lower detection accuracy during wakefulness. Figure 1 shows the relationship between the percentage of correct measurements during sleep and the apnea-hypopnea index in all participants.

Bottom Line: The monitor's measurements were obtained at 4-minute intervals and compared to actual oxygen use determined by review of time-synchronized video recordings.All errors were false negatives, ie, the monitor failed to detect that the participant was actually wearing the cannula.Application of a majority-vote filter to the raw data improved overall detection accuracy to 84.9%.

View Article: PubMed Central - PubMed

Affiliation: Department of Bioengineering, University of Pennsylvania, Philadelphia 19104, USA.

ABSTRACT

Rationale: We have developed a novel oxygen adherence monitor that objectively measures patient use of long-term oxygen therapy. The monitor attaches to the oxygen source and detects whether or not the patient is wearing the nasal cannula.

Objective: The study's purpose was to validate the monitor's performance in patients with chronic obstructive pulmonary disease during wakefulness and sleep.

Methods: Ten adult males with stable chronic obstructive pulmonary disease (mean +/- SD FEV1 37.7 +/- 14.9% of predicted) on long-term continuous oxygen therapy were tested in a sleep laboratory over a 12-13 hour period that included an overnight polysomnogram.

Measurements: The monitor's measurements were obtained at 4-minute intervals and compared to actual oxygen use determined by review of time-synchronized video recordings.

Main results: The monitor made 1504/1888 (79.7%) correct detections (unprocessed data) across all participants: 957/1,118 (85.6%) correct detections during wakefulness and 546/770 (70.9%) during sleep. All errors were false negatives, ie, the monitor failed to detect that the participant was actually wearing the cannula. Application of a majority-vote filter to the raw data improved overall detection accuracy to 84.9%.

Conclusions: The results demonstrate the monitor's ability to objectively measure whether or not men with chronic obstructive pulmonary disease are receiving their oxygen treatment. The ability to objectively measure oxygen delivery, rather than oxygen expended, may help improve the management of patients on long-term oxygen therapy.

Show MeSH
Related in: MedlinePlus