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Disc hemorrhages in patients with both normal tension glaucoma and branch retinal vein occlusion in different eyes.

Yoo YC, Park KH - Korean J Ophthalmol (2007)

Bottom Line: The frequency and location of disc hemorrhages, history of associated systemic diseases, and the order of the time of diagnosis between NTG and BRVO were studied.A higher frequency of disc hemorrhages was identified in patients with both BRVO and NTG.Therefore, some cases of NTG, especially with disc hemorrhages, may share a common vascular pathophysiology with BRVO.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Hallym University College of Medicine, Seoul, Korea.

ABSTRACT

Purpose: To document the clinical features of disc hemorrhage in patients with branch retinal vein occlusion (BRVO) and normal tension glaucoma (NTG), and to evaluate the relationship between BRVO and NTG with disc hemorrhages.

Methods: From July 2001 to May 2006, sixteen patients with both NTG and BRVO in different eyes were successively collected from outpatient population of Seoul National University Hospital in this observational case series. The frequency and location of disc hemorrhages, history of associated systemic diseases, and the order of the time of diagnosis between NTG and BRVO were studied.

Results: All patients had unilateral BRVO, and their mean age was 63.3+/-10.6 years. Disc hemorrhages were detected in eight patients (50%) during the mean follow-up of 26.8 months (range, 3-96 months). Six patients (75%) had disc hemorrhages in the non-BRVO eyes and two patients (25%) in BRVO eyes. Five hemorrhages (62.5%) were located at inferior-temporal quadrant of the optic disc. History of systemic hypertension was identified in 12 patients (75.0%). In 11 patients (68.8%), NTG was diagnosed at the same time as BRVO.

Conclusions: A higher frequency of disc hemorrhages was identified in patients with both BRVO and NTG. Therefore, some cases of NTG, especially with disc hemorrhages, may share a common vascular pathophysiology with BRVO.

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Related in: MedlinePlus

Retinal nerve fiber layer (RNFL) photographs and fluorescein angiogram of a 73 year-old male patient (Case 1). (A) Right eye shows a small, splint hemorrhage at 7 o'clock of disc (white arrow), and vascular sheathing and retinal hemorrhages at superior temporal quadrant. Fluorescein angiography of right eye (inset picture), taken 3 months prior to RNFL photographies, shows a venous filling delay at superior temporal quadrant. (B) Left eye shows diffuse thinning of RNFL.
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Figure 2: Retinal nerve fiber layer (RNFL) photographs and fluorescein angiogram of a 73 year-old male patient (Case 1). (A) Right eye shows a small, splint hemorrhage at 7 o'clock of disc (white arrow), and vascular sheathing and retinal hemorrhages at superior temporal quadrant. Fluorescein angiography of right eye (inset picture), taken 3 months prior to RNFL photographies, shows a venous filling delay at superior temporal quadrant. (B) Left eye shows diffuse thinning of RNFL.

Mentions: The sites of all retinal vein occlusion were at the arteriovenous crossings in all patients. The most frequent quadrants of retina of the segmentally involved BRVO was the inferior-temporal (37.5%) and superior-temporal quadrants (43.7%). During the follow-up period, disc hemorrhages were detected in eight patients (50.0%). Six (75%) of these patients had disc hemorrhages in the non-BRVO eyes with NTG (Fig. 1) and two patients (25%) had disc hemorrhages in the eyes with BRVO, which were in the opposite hemispheres each other (Fig. 2). All disc hemorrhages were located at the temporal side, especially the inferior-temporal quadrant (Table 2).


Disc hemorrhages in patients with both normal tension glaucoma and branch retinal vein occlusion in different eyes.

Yoo YC, Park KH - Korean J Ophthalmol (2007)

Retinal nerve fiber layer (RNFL) photographs and fluorescein angiogram of a 73 year-old male patient (Case 1). (A) Right eye shows a small, splint hemorrhage at 7 o'clock of disc (white arrow), and vascular sheathing and retinal hemorrhages at superior temporal quadrant. Fluorescein angiography of right eye (inset picture), taken 3 months prior to RNFL photographies, shows a venous filling delay at superior temporal quadrant. (B) Left eye shows diffuse thinning of RNFL.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2629887&req=5

Figure 2: Retinal nerve fiber layer (RNFL) photographs and fluorescein angiogram of a 73 year-old male patient (Case 1). (A) Right eye shows a small, splint hemorrhage at 7 o'clock of disc (white arrow), and vascular sheathing and retinal hemorrhages at superior temporal quadrant. Fluorescein angiography of right eye (inset picture), taken 3 months prior to RNFL photographies, shows a venous filling delay at superior temporal quadrant. (B) Left eye shows diffuse thinning of RNFL.
Mentions: The sites of all retinal vein occlusion were at the arteriovenous crossings in all patients. The most frequent quadrants of retina of the segmentally involved BRVO was the inferior-temporal (37.5%) and superior-temporal quadrants (43.7%). During the follow-up period, disc hemorrhages were detected in eight patients (50.0%). Six (75%) of these patients had disc hemorrhages in the non-BRVO eyes with NTG (Fig. 1) and two patients (25%) had disc hemorrhages in the eyes with BRVO, which were in the opposite hemispheres each other (Fig. 2). All disc hemorrhages were located at the temporal side, especially the inferior-temporal quadrant (Table 2).

Bottom Line: The frequency and location of disc hemorrhages, history of associated systemic diseases, and the order of the time of diagnosis between NTG and BRVO were studied.A higher frequency of disc hemorrhages was identified in patients with both BRVO and NTG.Therefore, some cases of NTG, especially with disc hemorrhages, may share a common vascular pathophysiology with BRVO.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Hallym University College of Medicine, Seoul, Korea.

ABSTRACT

Purpose: To document the clinical features of disc hemorrhage in patients with branch retinal vein occlusion (BRVO) and normal tension glaucoma (NTG), and to evaluate the relationship between BRVO and NTG with disc hemorrhages.

Methods: From July 2001 to May 2006, sixteen patients with both NTG and BRVO in different eyes were successively collected from outpatient population of Seoul National University Hospital in this observational case series. The frequency and location of disc hemorrhages, history of associated systemic diseases, and the order of the time of diagnosis between NTG and BRVO were studied.

Results: All patients had unilateral BRVO, and their mean age was 63.3+/-10.6 years. Disc hemorrhages were detected in eight patients (50%) during the mean follow-up of 26.8 months (range, 3-96 months). Six patients (75%) had disc hemorrhages in the non-BRVO eyes and two patients (25%) in BRVO eyes. Five hemorrhages (62.5%) were located at inferior-temporal quadrant of the optic disc. History of systemic hypertension was identified in 12 patients (75.0%). In 11 patients (68.8%), NTG was diagnosed at the same time as BRVO.

Conclusions: A higher frequency of disc hemorrhages was identified in patients with both BRVO and NTG. Therefore, some cases of NTG, especially with disc hemorrhages, may share a common vascular pathophysiology with BRVO.

Show MeSH
Related in: MedlinePlus