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The effect of diffuse lamellar keratitis on visual acuity and contrast sensitivity following LASIK.

Han ES, Wee WR, Lee JH, Kim MK - Korean J Ophthalmol (2007)

Bottom Line: There was no difference in logMAR visual acuity between the DLK and non-DLK groups until the sixth postoperative month.However, CS was significantly decreased at 12 and 18 cycle/degree compared with preoperative values (p=0.043 and p=0.045, respectively) in the DLK group, whereas CS was significantly increased at 12 cycle/degree in the non-DLK group (p=0.042) at six months.DLK seemed to be strongly associated with a postoperative decrease of CS.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Seoul National University College of Medicine, Chongno-gu, Seoul, Korea.

ABSTRACT

Purpose: To evaluate visual outcome and the changes of contrast sensitivity (CS) after diffuse lamellar keratitis (DLK).

Methods: Using retrospective chart review, 48 eyes of 25 patients who underwent laser in situ keratomileusis (LASIK) with Visx S4 (VISX Inc., Santa Clara, CA) and M2 (Moria, France) and who were followed for at least six months were included. They were divided into two groups: DLK and non-DLK, by diagnosis of DLK or its absence after LASIK. Postoperative logMAR visual acuities and logCS measured using the VCTS 6500 (Vistech Consultants, Inc., Dayton, OH) were compared with preoperative values in the DLK and non-DLK groups at three and six months after LASIK.

Results: There was no difference in logMAR visual acuity between the DLK and non-DLK groups until the sixth postoperative month. However, CS was significantly decreased at 12 and 18 cycle/degree compared with preoperative values (p=0.043 and p=0.045, respectively) in the DLK group, whereas CS was significantly increased at 12 cycle/degree in the non-DLK group (p=0.042) at six months.

Conclusions: DLK seemed to be strongly associated with a postoperative decrease of CS.

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Related in: MedlinePlus

Comparison of the changes of visual acuity between the DLK and non-DLK groups following LASIK. The visual acuity of the non-DLK group was better at all times, but the difference was not statistically significant (p>0.05). MAR, minimal angle of resolutions; V/A, visual acuity; DLK, diffuse lamellar keratitis; preop, preoperative.
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Figure 1: Comparison of the changes of visual acuity between the DLK and non-DLK groups following LASIK. The visual acuity of the non-DLK group was better at all times, but the difference was not statistically significant (p>0.05). MAR, minimal angle of resolutions; V/A, visual acuity; DLK, diffuse lamellar keratitis; preop, preoperative.

Mentions: Of the 48 eyes included in this study, mean preoperative logMAR BCVA of the DLK group was -0.021, which was not statistically different from that of the non-DLK group (-0.037, p>0.05, Mann-Whitney U test). Mean logMAR UCVA at one, three, and six months following LASIK was 0.001, 0.016, and -0.007 in the DLK group, and -0.035, -0.007, and -0.050 in the non-DLK group, respectively. There were no changes of logMAR UCVA up to six months, compared with the preoperative BCVA in each group (p>0.05, Wilcoxon signed rank test). Furthermore, there was no significant difference in postoperative UCVA between the two groups up to six months (p>0.05, Mann-Whitney U test, Fig. 1). The mean preoperative Snellen BCVA of five eyes with grade 2 DLK was 1.16, and the mean UCVA at postoperative one, three, and six months were 1.02, 0.84, and 0.93, respectively. The preoperative UCVA of the eye with grade 3 DLK was 0.8, and there were no visual acuity change more than two lines up to six postoperative months. Sixteen eyes with grade 1 DLK and 26 without DLK showed no significant difference in mean visual acuity preoperatively and postoperatively up to six months (p>0.05, Mann-Whitney U test).


The effect of diffuse lamellar keratitis on visual acuity and contrast sensitivity following LASIK.

Han ES, Wee WR, Lee JH, Kim MK - Korean J Ophthalmol (2007)

Comparison of the changes of visual acuity between the DLK and non-DLK groups following LASIK. The visual acuity of the non-DLK group was better at all times, but the difference was not statistically significant (p>0.05). MAR, minimal angle of resolutions; V/A, visual acuity; DLK, diffuse lamellar keratitis; preop, preoperative.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2629693&req=5

Figure 1: Comparison of the changes of visual acuity between the DLK and non-DLK groups following LASIK. The visual acuity of the non-DLK group was better at all times, but the difference was not statistically significant (p>0.05). MAR, minimal angle of resolutions; V/A, visual acuity; DLK, diffuse lamellar keratitis; preop, preoperative.
Mentions: Of the 48 eyes included in this study, mean preoperative logMAR BCVA of the DLK group was -0.021, which was not statistically different from that of the non-DLK group (-0.037, p>0.05, Mann-Whitney U test). Mean logMAR UCVA at one, three, and six months following LASIK was 0.001, 0.016, and -0.007 in the DLK group, and -0.035, -0.007, and -0.050 in the non-DLK group, respectively. There were no changes of logMAR UCVA up to six months, compared with the preoperative BCVA in each group (p>0.05, Wilcoxon signed rank test). Furthermore, there was no significant difference in postoperative UCVA between the two groups up to six months (p>0.05, Mann-Whitney U test, Fig. 1). The mean preoperative Snellen BCVA of five eyes with grade 2 DLK was 1.16, and the mean UCVA at postoperative one, three, and six months were 1.02, 0.84, and 0.93, respectively. The preoperative UCVA of the eye with grade 3 DLK was 0.8, and there were no visual acuity change more than two lines up to six postoperative months. Sixteen eyes with grade 1 DLK and 26 without DLK showed no significant difference in mean visual acuity preoperatively and postoperatively up to six months (p>0.05, Mann-Whitney U test).

Bottom Line: There was no difference in logMAR visual acuity between the DLK and non-DLK groups until the sixth postoperative month.However, CS was significantly decreased at 12 and 18 cycle/degree compared with preoperative values (p=0.043 and p=0.045, respectively) in the DLK group, whereas CS was significantly increased at 12 cycle/degree in the non-DLK group (p=0.042) at six months.DLK seemed to be strongly associated with a postoperative decrease of CS.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Seoul National University College of Medicine, Chongno-gu, Seoul, Korea.

ABSTRACT

Purpose: To evaluate visual outcome and the changes of contrast sensitivity (CS) after diffuse lamellar keratitis (DLK).

Methods: Using retrospective chart review, 48 eyes of 25 patients who underwent laser in situ keratomileusis (LASIK) with Visx S4 (VISX Inc., Santa Clara, CA) and M2 (Moria, France) and who were followed for at least six months were included. They were divided into two groups: DLK and non-DLK, by diagnosis of DLK or its absence after LASIK. Postoperative logMAR visual acuities and logCS measured using the VCTS 6500 (Vistech Consultants, Inc., Dayton, OH) were compared with preoperative values in the DLK and non-DLK groups at three and six months after LASIK.

Results: There was no difference in logMAR visual acuity between the DLK and non-DLK groups until the sixth postoperative month. However, CS was significantly decreased at 12 and 18 cycle/degree compared with preoperative values (p=0.043 and p=0.045, respectively) in the DLK group, whereas CS was significantly increased at 12 cycle/degree in the non-DLK group (p=0.042) at six months.

Conclusions: DLK seemed to be strongly associated with a postoperative decrease of CS.

Show MeSH
Related in: MedlinePlus