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Bilateral peripheral infiltrative keratitis after LASIK.

Moon SW, Kim YH, Lee SC, Lee MA, Jin KH - Korean J Ophthalmol (2007)

Bottom Line: The flap was lifted and irrigation was performed with antibiotics. but infiltration seemed to appear again.Direct smear and culture for bacteria and fungus were negative.Topical prednisolone acetate 1% eye drops was added, infiltrative condition was resolved.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Kyung Hee University College of Medicine, Seoul, Korea.

ABSTRACT

Purpose: To present a case of peripheral infiltrative keratitis mimicking infectious keratitis on the flap margin and limbus, which appeared on the first postoperative day after the laser in situ keratomileusis (LASIK).

Methods: A 36-year-old woman who underwent uneventful bilateral simultaneous LASIK developed multiple round infiltrate along the flap margin reaching to limbus from the 11 o'clock to 6 o'clock area in both eyes.

Results: The flap was lifted and irrigation was performed with antibiotics. but infiltration seemed to appear again. The infiltrate was more concentrated at the periphery and was extended to the limbus. Direct smear and culture for bacteria and fungus were negative. Topical prednisolone acetate 1% eye drops was added, infiltrative condition was resolved.

Conclusions: LASIK induced peripheral infiltrative keratitis, in which infectious origin was ruled out, is reported.

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Related in: MedlinePlus

Peripheral flap infiltration was progressed into the limbus in second day after flap lifting with antibiotics irrigation. (A: right eye, B: left eye)
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Figure 2: Peripheral flap infiltration was progressed into the limbus in second day after flap lifting with antibiotics irrigation. (A: right eye, B: left eye)

Mentions: During flap lifting and antibiotics irrigation, bacterial and fungal culture were obtained. 0.5% moxifloxacin eye drops and fortified vancomycin 50 mg/ml eye drops were given in each eye for 4 times a day. The infiltration seemed to improve, but on the 2nd day after operation, the infiltrate had developed to involve the flap edge from the 2 o'clock to 11 o'clock direction and also involved the limbus in both eyes. Direct smear and culture for bacteria and fungus were negative. Blood tests were performed for human immunodeficiency disease, hepatitis B surface antigen, hepatitis C antigen, rheumatoid factor, and C-reactive protein, but they all turned out negative also. But the infiltrate did not advance centrally, alone with topical antibiotics, its margin appearing clear (Fig. 2). We started administrating 1% topical prednisolone acetate eye drops every 3 hours.


Bilateral peripheral infiltrative keratitis after LASIK.

Moon SW, Kim YH, Lee SC, Lee MA, Jin KH - Korean J Ophthalmol (2007)

Peripheral flap infiltration was progressed into the limbus in second day after flap lifting with antibiotics irrigation. (A: right eye, B: left eye)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2629674&req=5

Figure 2: Peripheral flap infiltration was progressed into the limbus in second day after flap lifting with antibiotics irrigation. (A: right eye, B: left eye)
Mentions: During flap lifting and antibiotics irrigation, bacterial and fungal culture were obtained. 0.5% moxifloxacin eye drops and fortified vancomycin 50 mg/ml eye drops were given in each eye for 4 times a day. The infiltration seemed to improve, but on the 2nd day after operation, the infiltrate had developed to involve the flap edge from the 2 o'clock to 11 o'clock direction and also involved the limbus in both eyes. Direct smear and culture for bacteria and fungus were negative. Blood tests were performed for human immunodeficiency disease, hepatitis B surface antigen, hepatitis C antigen, rheumatoid factor, and C-reactive protein, but they all turned out negative also. But the infiltrate did not advance centrally, alone with topical antibiotics, its margin appearing clear (Fig. 2). We started administrating 1% topical prednisolone acetate eye drops every 3 hours.

Bottom Line: The flap was lifted and irrigation was performed with antibiotics. but infiltration seemed to appear again.Direct smear and culture for bacteria and fungus were negative.Topical prednisolone acetate 1% eye drops was added, infiltrative condition was resolved.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Kyung Hee University College of Medicine, Seoul, Korea.

ABSTRACT

Purpose: To present a case of peripheral infiltrative keratitis mimicking infectious keratitis on the flap margin and limbus, which appeared on the first postoperative day after the laser in situ keratomileusis (LASIK).

Methods: A 36-year-old woman who underwent uneventful bilateral simultaneous LASIK developed multiple round infiltrate along the flap margin reaching to limbus from the 11 o'clock to 6 o'clock area in both eyes.

Results: The flap was lifted and irrigation was performed with antibiotics. but infiltration seemed to appear again. The infiltrate was more concentrated at the periphery and was extended to the limbus. Direct smear and culture for bacteria and fungus were negative. Topical prednisolone acetate 1% eye drops was added, infiltrative condition was resolved.

Conclusions: LASIK induced peripheral infiltrative keratitis, in which infectious origin was ruled out, is reported.

Show MeSH
Related in: MedlinePlus