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A solitary fibrofolliculoma in the eyelid.

Chang JK, Lee DC, Chang MH - Korean J Ophthalmol (2007)

Bottom Line: A 37-year-old female patient visited the outpatient department with a lesion in the right upper lid that had been growing steadily for a year.The 5x5 mm lesion was located near the upper lid margin.It was a red, hemispheric, smooth nodule, relatively solid to palpation and not painful.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Dankook University College of Medicine, Cheonan, Korea.

ABSTRACT

Purpose: To report the first case of a solitary eyelid fibrofolliculoma and to review the literature.

Methods: A 37-year-old female patient visited the outpatient department with a lesion in the right upper lid that had been growing steadily for a year. The patient had visited the local clinic, and under the diagnosis of chalazion had received incision and curettage twice, but the lesion had recurred.

Results: The 5x5 mm lesion was located near the upper lid margin. It was a red, hemispheric, smooth nodule, relatively solid to palpation and not painful. Excision and biopsy were performed, and through a histological exam, the diagnosis of fibrofolliculoma was later confirmed.

Conclusions: Solitary fibrofolliculoma is rare, and to the authors' knowledge, a lesion arising in the eyelid has not yet been reported. Fibrofolliculoma should be included in the differential diagnosis when a localized mass lesion arising in the eyelid is encountered.

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Related in: MedlinePlus

Low-power histopathologic appearance of a fibrofolliculoma showing proliferation of fibrotic stroma surrounding the central dilated infundibulum of the hair follicle with proliferative thin epithelial strands (Hematoxylin-eosin stain ×40).
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Figure 2: Low-power histopathologic appearance of a fibrofolliculoma showing proliferation of fibrotic stroma surrounding the central dilated infundibulum of the hair follicle with proliferative thin epithelial strands (Hematoxylin-eosin stain ×40).

Mentions: Histological examination revealed a well-defined tumor mass involving a group of adjacent pilosebaceous follicles and proliferative epithelial cords and spurs in the center, with a surrounding fibromucinous mesenchymal component (Fig. 2). Characteristic proliferating infundibular epithelial strands with perifollicular fibrous reaction anastomosing to form an epithelial network were also observed (Fig. 3). Pathological examination confirmed the diagnosis of fibrofolliculoma. The authors reexamined the patient's skin on the face, neck, axillae, upper trunk, and groin but obtained no particular findings. The patient indicated that she had no family history of multiple skin papules or any skin diseases. The authors made the final diagnosis of solitary fibrofolliculoma.


A solitary fibrofolliculoma in the eyelid.

Chang JK, Lee DC, Chang MH - Korean J Ophthalmol (2007)

Low-power histopathologic appearance of a fibrofolliculoma showing proliferation of fibrotic stroma surrounding the central dilated infundibulum of the hair follicle with proliferative thin epithelial strands (Hematoxylin-eosin stain ×40).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2629673&req=5

Figure 2: Low-power histopathologic appearance of a fibrofolliculoma showing proliferation of fibrotic stroma surrounding the central dilated infundibulum of the hair follicle with proliferative thin epithelial strands (Hematoxylin-eosin stain ×40).
Mentions: Histological examination revealed a well-defined tumor mass involving a group of adjacent pilosebaceous follicles and proliferative epithelial cords and spurs in the center, with a surrounding fibromucinous mesenchymal component (Fig. 2). Characteristic proliferating infundibular epithelial strands with perifollicular fibrous reaction anastomosing to form an epithelial network were also observed (Fig. 3). Pathological examination confirmed the diagnosis of fibrofolliculoma. The authors reexamined the patient's skin on the face, neck, axillae, upper trunk, and groin but obtained no particular findings. The patient indicated that she had no family history of multiple skin papules or any skin diseases. The authors made the final diagnosis of solitary fibrofolliculoma.

Bottom Line: A 37-year-old female patient visited the outpatient department with a lesion in the right upper lid that had been growing steadily for a year.The 5x5 mm lesion was located near the upper lid margin.It was a red, hemispheric, smooth nodule, relatively solid to palpation and not painful.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Dankook University College of Medicine, Cheonan, Korea.

ABSTRACT

Purpose: To report the first case of a solitary eyelid fibrofolliculoma and to review the literature.

Methods: A 37-year-old female patient visited the outpatient department with a lesion in the right upper lid that had been growing steadily for a year. The patient had visited the local clinic, and under the diagnosis of chalazion had received incision and curettage twice, but the lesion had recurred.

Results: The 5x5 mm lesion was located near the upper lid margin. It was a red, hemispheric, smooth nodule, relatively solid to palpation and not painful. Excision and biopsy were performed, and through a histological exam, the diagnosis of fibrofolliculoma was later confirmed.

Conclusions: Solitary fibrofolliculoma is rare, and to the authors' knowledge, a lesion arising in the eyelid has not yet been reported. Fibrofolliculoma should be included in the differential diagnosis when a localized mass lesion arising in the eyelid is encountered.

Show MeSH
Related in: MedlinePlus