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Comparison of CT-guided sclerotherapy with using 95% ethanol and 20% hypertonic saline for managing simple renal cyst.

Egilmez H, Gok V, Oztoprak I, Atalar M, Cetin A, Arslan M, Gultekin Y, Solak O - Korean J Radiol (2007 Nov-Dec)

Bottom Line: Treatment success was determined six months later with follow-up clinical evaluation and performing ultrasonography.The complete regression ratio of the ethanol group was significantly higher (94% versus 72%, respectively) than that of the HS group.The failure ratio of the ethanol group was significantly lower (3% versus 25%, respectively) than that of the HS group.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Cumhuriyet University School of Medicine, Sivas, Turkey. hegilmez@cumhuriyet.edu.tr

ABSTRACT

Objective: We wanted to compare the efficacies of 95% ethanol and 20% hypertonic saline (HS) sclerotherapies that were performed in a single session under CT guidance for the management of simple renal cysts.

Materials and methods: A prospective series of 74 consecutive patients (average age: 57.6 +/- 8.1 years) with simple renal cysts were enrolled in this study. They were randomized into two groups and 95% ethanol or 20% HS, respectively, corresponding to 25% of the aspiration volume, was injected. Treatment success was determined six months later with follow-up clinical evaluation and performing ultrasonography.

Results: The sclerotherapy was accepted as technically successful without major complications in all except two patients who were excluded because of a communication between the simple renal cyst and the pelvicalyceal collecting system. Thirty-six patients in the ethanol group received sclerotherapy with 95% ethanol and 36 patients in the HS group underwent sclerotherapy with 20% HS. The complete regression ratio of the ethanol group was significantly higher (94% versus 72%, respectively) than that of the HS group. There was one patient with partial regression in each group. The failure ratio of the ethanol group was significantly lower (3% versus 25%, respectively) than that of the HS group.

Conclusion: Ethanol sclerotherapy under CT guidance is a successful and safe procedure and it can be used for the treatment of simple renal cysts. Sclerotherapy with 95% ethanol is more effective than 20% HS sclerotherapy. Sclerotherapy with HS may be an option for patients preferring to undergo a less painful treatment procedure.

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Related in: MedlinePlus

Scatter dot plot with median line graphics of the volume of the simple renal cysts in the ethanol and hypertonic saline groups. There was no significant difference of the cyst volume between the study groups (p = 0.995).
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Figure 2: Scatter dot plot with median line graphics of the volume of the simple renal cysts in the ethanol and hypertonic saline groups. There was no significant difference of the cyst volume between the study groups (p = 0.995).

Mentions: Figure 2 presents the volume of the simple renal cysts in the ethanol and hypertonic saline groups. There was no significant difference between the ethanol and hypertonic saline groups for the median volume of the simple renal cysts (165 [52-480] vs. 178 [42-520] cm3, respectively, p = 0.995).


Comparison of CT-guided sclerotherapy with using 95% ethanol and 20% hypertonic saline for managing simple renal cyst.

Egilmez H, Gok V, Oztoprak I, Atalar M, Cetin A, Arslan M, Gultekin Y, Solak O - Korean J Radiol (2007 Nov-Dec)

Scatter dot plot with median line graphics of the volume of the simple renal cysts in the ethanol and hypertonic saline groups. There was no significant difference of the cyst volume between the study groups (p = 0.995).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2627454&req=5

Figure 2: Scatter dot plot with median line graphics of the volume of the simple renal cysts in the ethanol and hypertonic saline groups. There was no significant difference of the cyst volume between the study groups (p = 0.995).
Mentions: Figure 2 presents the volume of the simple renal cysts in the ethanol and hypertonic saline groups. There was no significant difference between the ethanol and hypertonic saline groups for the median volume of the simple renal cysts (165 [52-480] vs. 178 [42-520] cm3, respectively, p = 0.995).

Bottom Line: Treatment success was determined six months later with follow-up clinical evaluation and performing ultrasonography.The complete regression ratio of the ethanol group was significantly higher (94% versus 72%, respectively) than that of the HS group.The failure ratio of the ethanol group was significantly lower (3% versus 25%, respectively) than that of the HS group.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Cumhuriyet University School of Medicine, Sivas, Turkey. hegilmez@cumhuriyet.edu.tr

ABSTRACT

Objective: We wanted to compare the efficacies of 95% ethanol and 20% hypertonic saline (HS) sclerotherapies that were performed in a single session under CT guidance for the management of simple renal cysts.

Materials and methods: A prospective series of 74 consecutive patients (average age: 57.6 +/- 8.1 years) with simple renal cysts were enrolled in this study. They were randomized into two groups and 95% ethanol or 20% HS, respectively, corresponding to 25% of the aspiration volume, was injected. Treatment success was determined six months later with follow-up clinical evaluation and performing ultrasonography.

Results: The sclerotherapy was accepted as technically successful without major complications in all except two patients who were excluded because of a communication between the simple renal cyst and the pelvicalyceal collecting system. Thirty-six patients in the ethanol group received sclerotherapy with 95% ethanol and 36 patients in the HS group underwent sclerotherapy with 20% HS. The complete regression ratio of the ethanol group was significantly higher (94% versus 72%, respectively) than that of the HS group. There was one patient with partial regression in each group. The failure ratio of the ethanol group was significantly lower (3% versus 25%, respectively) than that of the HS group.

Conclusion: Ethanol sclerotherapy under CT guidance is a successful and safe procedure and it can be used for the treatment of simple renal cysts. Sclerotherapy with 95% ethanol is more effective than 20% HS sclerotherapy. Sclerotherapy with HS may be an option for patients preferring to undergo a less painful treatment procedure.

Show MeSH
Related in: MedlinePlus