Limits...
Spontaneous regression of pulmonary and adrenal metastases following percutaneous radiofrequency ablation of a recurrent renal cell carcinoma.

Kim H, Park BK, Kim CK - Korean J Radiol (2008 Sep-Oct)

Bottom Line: The spontaneous regression of metastatic lesions from renal cell carcinoma (RCC) is extremely rare, but may be encountered following cytoreductive treatments.We report a case of a recurrent RCC with multiple metastatic lesions which spontaneously regressed after undergoing radiofrequency ablation of the renal tumor.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

ABSTRACT
The spontaneous regression of metastatic lesions from renal cell carcinoma (RCC) is extremely rare, but may be encountered following cytoreductive treatments. We report a case of a recurrent RCC with multiple metastatic lesions which spontaneously regressed after undergoing radiofrequency ablation of the renal tumor.

Show MeSH

Related in: MedlinePlus

80-year-old man with multiple metastatic lesions from previously removed renal cell carcinoma.A. Pre-ablation abdomen CT shows well-enhancing solid tumor (arrows) arising from site of previous partial nephrectomy, which suggests recurrent renal cell carcinoma.B. Chest CT, which was performed prior to radiofrequency ablation, shows well-defined metastatic nodule in right upper lobe of lung (arrow). Lesion has maximum diameter of 10 mm.C. Pre-ablation abdomen CT shows well-enhancing tumor (arrow) arising from right adrenal gland. Lesion has maximum diameter of 1.8 cm. CT image was obtained in supine position of patient.D. Post-ablation abdomen CT performed 10 months after radiofrequency ablation shows lack of tumor enhancement within tumor, which suggests complete ablation (arrows).E. Chest CT performed 10 months after radiofrequency ablation reveals that nodule (arrow) is significantly reduced and maximum diameter cannot be measured.F. Post-ablation abdomen CT shows that right adrenal mass (arrow) decreases to one-half volume (1.4-cm maximum diameter). This CT image was obtained in prone position of patient.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC2627212&req=5

Figure 1: 80-year-old man with multiple metastatic lesions from previously removed renal cell carcinoma.A. Pre-ablation abdomen CT shows well-enhancing solid tumor (arrows) arising from site of previous partial nephrectomy, which suggests recurrent renal cell carcinoma.B. Chest CT, which was performed prior to radiofrequency ablation, shows well-defined metastatic nodule in right upper lobe of lung (arrow). Lesion has maximum diameter of 10 mm.C. Pre-ablation abdomen CT shows well-enhancing tumor (arrow) arising from right adrenal gland. Lesion has maximum diameter of 1.8 cm. CT image was obtained in supine position of patient.D. Post-ablation abdomen CT performed 10 months after radiofrequency ablation shows lack of tumor enhancement within tumor, which suggests complete ablation (arrows).E. Chest CT performed 10 months after radiofrequency ablation reveals that nodule (arrow) is significantly reduced and maximum diameter cannot be measured.F. Post-ablation abdomen CT shows that right adrenal mass (arrow) decreases to one-half volume (1.4-cm maximum diameter). This CT image was obtained in prone position of patient.

Mentions: The institutional review board approved this case report prior to any review of medical records. An 80-year-old man was transferred to our institute because of an incidentally detected renal tumor. The patient underwent a right partial nephrectomy due to a previously diagnosed RCC eight years prior. Recent routine follow-up CT images, which covered the lung and abdomen, revealed a right renal mass, a right adrenal mass, and three pulmonary nodules; all of which were not seen on prior CT images (Figs. 1A-C). The right renal tumor and adrenal tumor had maximum diameters measuring 2.0 cm and 1.8 cm, respectively. In addition, the pulmonary nodules, with maximum diameters ranging from 8 to 10 mm, were seen in the right upper lobe, left upper lobe, and left lower lobe. The treatment modality decided upon was an RF ablation for the cytoreductive removal of the right renal tumor. However, the histological results were not confirmed before the ablation as these lesions were clinically considered to be recurrent or as metastatic lesions from the previously removed RCC.


Spontaneous regression of pulmonary and adrenal metastases following percutaneous radiofrequency ablation of a recurrent renal cell carcinoma.

Kim H, Park BK, Kim CK - Korean J Radiol (2008 Sep-Oct)

80-year-old man with multiple metastatic lesions from previously removed renal cell carcinoma.A. Pre-ablation abdomen CT shows well-enhancing solid tumor (arrows) arising from site of previous partial nephrectomy, which suggests recurrent renal cell carcinoma.B. Chest CT, which was performed prior to radiofrequency ablation, shows well-defined metastatic nodule in right upper lobe of lung (arrow). Lesion has maximum diameter of 10 mm.C. Pre-ablation abdomen CT shows well-enhancing tumor (arrow) arising from right adrenal gland. Lesion has maximum diameter of 1.8 cm. CT image was obtained in supine position of patient.D. Post-ablation abdomen CT performed 10 months after radiofrequency ablation shows lack of tumor enhancement within tumor, which suggests complete ablation (arrows).E. Chest CT performed 10 months after radiofrequency ablation reveals that nodule (arrow) is significantly reduced and maximum diameter cannot be measured.F. Post-ablation abdomen CT shows that right adrenal mass (arrow) decreases to one-half volume (1.4-cm maximum diameter). This CT image was obtained in prone position of patient.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2627212&req=5

Figure 1: 80-year-old man with multiple metastatic lesions from previously removed renal cell carcinoma.A. Pre-ablation abdomen CT shows well-enhancing solid tumor (arrows) arising from site of previous partial nephrectomy, which suggests recurrent renal cell carcinoma.B. Chest CT, which was performed prior to radiofrequency ablation, shows well-defined metastatic nodule in right upper lobe of lung (arrow). Lesion has maximum diameter of 10 mm.C. Pre-ablation abdomen CT shows well-enhancing tumor (arrow) arising from right adrenal gland. Lesion has maximum diameter of 1.8 cm. CT image was obtained in supine position of patient.D. Post-ablation abdomen CT performed 10 months after radiofrequency ablation shows lack of tumor enhancement within tumor, which suggests complete ablation (arrows).E. Chest CT performed 10 months after radiofrequency ablation reveals that nodule (arrow) is significantly reduced and maximum diameter cannot be measured.F. Post-ablation abdomen CT shows that right adrenal mass (arrow) decreases to one-half volume (1.4-cm maximum diameter). This CT image was obtained in prone position of patient.
Mentions: The institutional review board approved this case report prior to any review of medical records. An 80-year-old man was transferred to our institute because of an incidentally detected renal tumor. The patient underwent a right partial nephrectomy due to a previously diagnosed RCC eight years prior. Recent routine follow-up CT images, which covered the lung and abdomen, revealed a right renal mass, a right adrenal mass, and three pulmonary nodules; all of which were not seen on prior CT images (Figs. 1A-C). The right renal tumor and adrenal tumor had maximum diameters measuring 2.0 cm and 1.8 cm, respectively. In addition, the pulmonary nodules, with maximum diameters ranging from 8 to 10 mm, were seen in the right upper lobe, left upper lobe, and left lower lobe. The treatment modality decided upon was an RF ablation for the cytoreductive removal of the right renal tumor. However, the histological results were not confirmed before the ablation as these lesions were clinically considered to be recurrent or as metastatic lesions from the previously removed RCC.

Bottom Line: The spontaneous regression of metastatic lesions from renal cell carcinoma (RCC) is extremely rare, but may be encountered following cytoreductive treatments.We report a case of a recurrent RCC with multiple metastatic lesions which spontaneously regressed after undergoing radiofrequency ablation of the renal tumor.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

ABSTRACT
The spontaneous regression of metastatic lesions from renal cell carcinoma (RCC) is extremely rare, but may be encountered following cytoreductive treatments. We report a case of a recurrent RCC with multiple metastatic lesions which spontaneously regressed after undergoing radiofrequency ablation of the renal tumor.

Show MeSH
Related in: MedlinePlus