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Carcinoma mixed within milk of calcium in a breast: a case report.

Park JS, Park YM, Kim EK, Lee JH, Kim OH, Ryu JH - Korean J Radiol (2008)

Bottom Line: Milk of calcium located in the breast is typically a benign entity.Consequently, the characteristics of all observed calcific particles should be carefully analyzed.In this study, we report a case of carcinoma presented as malignant microcalcifications mixed within milk of calcium in a breast.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Inje University College of Medicine, Busan, Korea.

ABSTRACT
Milk of calcium located in the breast is typically a benign entity. However, carcinoma may incidentally arise adjacent to or even within milk of calcium. Consequently, the characteristics of all observed calcific particles should be carefully analyzed. In this study, we report a case of carcinoma presented as malignant microcalcifications mixed within milk of calcium in a breast.

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Related in: MedlinePlus

Carcinoma mixed within milk of calcium of breast in 48-year-old woman.A, B. Craniocaudal (A) and true lateral (B) spot magnification mammograms show poorly defined smudges and typical semilunar sedimented calcium. In addition, within milk of calcium cluster, several fine pleomorphic microcalcifications (arrow), different in appearance from sedimented calcium, are observed.C. Specimen radiography, including microcalcifications, indicates successful excision of lesion.D. Histological specimen shows multiple cysts lined with malignant cells which contain microcalcifications (arrows) among cystic acini (arrowhead). (Hematoxylin & Eosin staining; magnification, ×40)
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Figure 1: Carcinoma mixed within milk of calcium of breast in 48-year-old woman.A, B. Craniocaudal (A) and true lateral (B) spot magnification mammograms show poorly defined smudges and typical semilunar sedimented calcium. In addition, within milk of calcium cluster, several fine pleomorphic microcalcifications (arrow), different in appearance from sedimented calcium, are observed.C. Specimen radiography, including microcalcifications, indicates successful excision of lesion.D. Histological specimen shows multiple cysts lined with malignant cells which contain microcalcifications (arrows) among cystic acini (arrowhead). (Hematoxylin & Eosin staining; magnification, ×40)

Mentions: A 48-year-old woman underwent a screening mammography. The crainocaudal and mediolateral oblique views divulged a cluster of microcalcifications in the right upper inner quadrant. Subsequent magnification mammograms revealed the poorly defined smudges on a craniocaudal projection, and the typical crescent-shaped sedimented calcium on a mediolateral projection, also known as the "teacup sign", suggestive of milk of calcium (4). However, among the milk of calcium clusters, several fine pleomorphic microcalcifications, which are distinct in appearance from sedimented calcium, were observed (Figs. 1A, B).


Carcinoma mixed within milk of calcium in a breast: a case report.

Park JS, Park YM, Kim EK, Lee JH, Kim OH, Ryu JH - Korean J Radiol (2008)

Carcinoma mixed within milk of calcium of breast in 48-year-old woman.A, B. Craniocaudal (A) and true lateral (B) spot magnification mammograms show poorly defined smudges and typical semilunar sedimented calcium. In addition, within milk of calcium cluster, several fine pleomorphic microcalcifications (arrow), different in appearance from sedimented calcium, are observed.C. Specimen radiography, including microcalcifications, indicates successful excision of lesion.D. Histological specimen shows multiple cysts lined with malignant cells which contain microcalcifications (arrows) among cystic acini (arrowhead). (Hematoxylin & Eosin staining; magnification, ×40)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2627184&req=5

Figure 1: Carcinoma mixed within milk of calcium of breast in 48-year-old woman.A, B. Craniocaudal (A) and true lateral (B) spot magnification mammograms show poorly defined smudges and typical semilunar sedimented calcium. In addition, within milk of calcium cluster, several fine pleomorphic microcalcifications (arrow), different in appearance from sedimented calcium, are observed.C. Specimen radiography, including microcalcifications, indicates successful excision of lesion.D. Histological specimen shows multiple cysts lined with malignant cells which contain microcalcifications (arrows) among cystic acini (arrowhead). (Hematoxylin & Eosin staining; magnification, ×40)
Mentions: A 48-year-old woman underwent a screening mammography. The crainocaudal and mediolateral oblique views divulged a cluster of microcalcifications in the right upper inner quadrant. Subsequent magnification mammograms revealed the poorly defined smudges on a craniocaudal projection, and the typical crescent-shaped sedimented calcium on a mediolateral projection, also known as the "teacup sign", suggestive of milk of calcium (4). However, among the milk of calcium clusters, several fine pleomorphic microcalcifications, which are distinct in appearance from sedimented calcium, were observed (Figs. 1A, B).

Bottom Line: Milk of calcium located in the breast is typically a benign entity.Consequently, the characteristics of all observed calcific particles should be carefully analyzed.In this study, we report a case of carcinoma presented as malignant microcalcifications mixed within milk of calcium in a breast.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Inje University College of Medicine, Busan, Korea.

ABSTRACT
Milk of calcium located in the breast is typically a benign entity. However, carcinoma may incidentally arise adjacent to or even within milk of calcium. Consequently, the characteristics of all observed calcific particles should be carefully analyzed. In this study, we report a case of carcinoma presented as malignant microcalcifications mixed within milk of calcium in a breast.

Show MeSH
Related in: MedlinePlus