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The role of PET/CT for evaluating breast cancer.

Yang SK, Cho N, Moon WK - Korean J Radiol (2007 Sep-Oct)

Bottom Line: Positron emission tomography combined with computed tomography (PET/CT) has been receiving increasing attention during the recent years for making the diagnosis, for determining the staging and for the follow-up of various malignancies.The PET/CT findings of 58 breast cancer patients (age range: 34-79 years old, mean age: 50 years) were retrospectively compared with the PET or CT scans alone.PET/CT was found to be better than PET or CT alone for detecting small tumors or multiple metastases, for accurately localizing lymph node metastasis and for monitoring the response to chemotherapy in breast cancer patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, College of Medicine Seoul National University and The Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea.

ABSTRACT
Positron emission tomography combined with computed tomography (PET/CT) has been receiving increasing attention during the recent years for making the diagnosis, for determining the staging and for the follow-up of various malignancies. The PET/CT findings of 58 breast cancer patients (age range: 34-79 years old, mean age: 50 years) were retrospectively compared with the PET or CT scans alone. PET/CT was found to be better than PET or CT alone for detecting small tumors or multiple metastases, for accurately localizing lymph node metastasis and for monitoring the response to chemotherapy in breast cancer patients.

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Local recurrence in a 74-year-old woman who had undergone right modified radical mastectomy eight years previously.A. Sonography shows an 1.4 cm oval mass with increased vascularity in the right pectoralis muscle at the mastectomy site.B, C. The PET images show focal high FDG uptake (SUV= 3.3) (arrows) in the right chest wall.D. The PET/CT image shows a focus of high FDG uptake (arrow) localized to the right pectoralis muscle. Accurate localization of the lesion was difficult with using PET alone.
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Figure 9: Local recurrence in a 74-year-old woman who had undergone right modified radical mastectomy eight years previously.A. Sonography shows an 1.4 cm oval mass with increased vascularity in the right pectoralis muscle at the mastectomy site.B, C. The PET images show focal high FDG uptake (SUV= 3.3) (arrows) in the right chest wall.D. The PET/CT image shows a focus of high FDG uptake (arrow) localized to the right pectoralis muscle. Accurate localization of the lesion was difficult with using PET alone.

Mentions: Grahek et al. studied 134 patients with suspected recurrence and they found that the sensitivity and specificity of PET for detecting recurrence were 84% and 78%, respectively, whereas the sensitivities and specificities of the conventional imaging modalities were 63% and 61%, respectively (25). PET is considered to be highly effective for evaluating patients with suspected recurrent breast cancer, and it surpasses the other conventional imaging modalities in terms of whole-body evaluation. The CT data from a PET/CT examination allows the appropriate anatomical localization of foci of FDG uptake (Fig. 9).


The role of PET/CT for evaluating breast cancer.

Yang SK, Cho N, Moon WK - Korean J Radiol (2007 Sep-Oct)

Local recurrence in a 74-year-old woman who had undergone right modified radical mastectomy eight years previously.A. Sonography shows an 1.4 cm oval mass with increased vascularity in the right pectoralis muscle at the mastectomy site.B, C. The PET images show focal high FDG uptake (SUV= 3.3) (arrows) in the right chest wall.D. The PET/CT image shows a focus of high FDG uptake (arrow) localized to the right pectoralis muscle. Accurate localization of the lesion was difficult with using PET alone.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2626817&req=5

Figure 9: Local recurrence in a 74-year-old woman who had undergone right modified radical mastectomy eight years previously.A. Sonography shows an 1.4 cm oval mass with increased vascularity in the right pectoralis muscle at the mastectomy site.B, C. The PET images show focal high FDG uptake (SUV= 3.3) (arrows) in the right chest wall.D. The PET/CT image shows a focus of high FDG uptake (arrow) localized to the right pectoralis muscle. Accurate localization of the lesion was difficult with using PET alone.
Mentions: Grahek et al. studied 134 patients with suspected recurrence and they found that the sensitivity and specificity of PET for detecting recurrence were 84% and 78%, respectively, whereas the sensitivities and specificities of the conventional imaging modalities were 63% and 61%, respectively (25). PET is considered to be highly effective for evaluating patients with suspected recurrent breast cancer, and it surpasses the other conventional imaging modalities in terms of whole-body evaluation. The CT data from a PET/CT examination allows the appropriate anatomical localization of foci of FDG uptake (Fig. 9).

Bottom Line: Positron emission tomography combined with computed tomography (PET/CT) has been receiving increasing attention during the recent years for making the diagnosis, for determining the staging and for the follow-up of various malignancies.The PET/CT findings of 58 breast cancer patients (age range: 34-79 years old, mean age: 50 years) were retrospectively compared with the PET or CT scans alone.PET/CT was found to be better than PET or CT alone for detecting small tumors or multiple metastases, for accurately localizing lymph node metastasis and for monitoring the response to chemotherapy in breast cancer patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, College of Medicine Seoul National University and The Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea.

ABSTRACT
Positron emission tomography combined with computed tomography (PET/CT) has been receiving increasing attention during the recent years for making the diagnosis, for determining the staging and for the follow-up of various malignancies. The PET/CT findings of 58 breast cancer patients (age range: 34-79 years old, mean age: 50 years) were retrospectively compared with the PET or CT scans alone. PET/CT was found to be better than PET or CT alone for detecting small tumors or multiple metastases, for accurately localizing lymph node metastasis and for monitoring the response to chemotherapy in breast cancer patients.

Show MeSH
Related in: MedlinePlus