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The role of PET/CT for evaluating breast cancer.

Yang SK, Cho N, Moon WK - Korean J Radiol (2007 Sep-Oct)

Bottom Line: Positron emission tomography combined with computed tomography (PET/CT) has been receiving increasing attention during the recent years for making the diagnosis, for determining the staging and for the follow-up of various malignancies.The PET/CT findings of 58 breast cancer patients (age range: 34-79 years old, mean age: 50 years) were retrospectively compared with the PET or CT scans alone.PET/CT was found to be better than PET or CT alone for detecting small tumors or multiple metastases, for accurately localizing lymph node metastasis and for monitoring the response to chemotherapy in breast cancer patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, College of Medicine Seoul National University and The Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea.

ABSTRACT
Positron emission tomography combined with computed tomography (PET/CT) has been receiving increasing attention during the recent years for making the diagnosis, for determining the staging and for the follow-up of various malignancies. The PET/CT findings of 58 breast cancer patients (age range: 34-79 years old, mean age: 50 years) were retrospectively compared with the PET or CT scans alone. PET/CT was found to be better than PET or CT alone for detecting small tumors or multiple metastases, for accurately localizing lymph node metastasis and for monitoring the response to chemotherapy in breast cancer patients.

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Mediastinal lymph node metastasis in a 41-year-old woman who had undergone left modified radical mastectomy 10 months previously.A. The PET image shows multiple areas of increased uptake (arrows) in the left upper chest.B. The CT image shows a small soft tissue density in the anterior mediastinum (arrow).C. The PET/CT image shows co-registration of the FDG uptake and the soft tissue density in the anterior mediastinum, suggesting internal mammary lymph node metastases (arrow).
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Figure 4: Mediastinal lymph node metastasis in a 41-year-old woman who had undergone left modified radical mastectomy 10 months previously.A. The PET image shows multiple areas of increased uptake (arrows) in the left upper chest.B. The CT image shows a small soft tissue density in the anterior mediastinum (arrow).C. The PET/CT image shows co-registration of the FDG uptake and the soft tissue density in the anterior mediastinum, suggesting internal mammary lymph node metastases (arrow).

Mentions: The metastasis to the internal mammary or mediastinal lymph nodes in breast cancer patients is often clinically occult. The prevalence of abnormal findings for the internal mammary or mediastinal lymph nodes by PET was about twice than of conventional CT in those patients with recurrent or metastatic breast cancer (15). In a study by Tatsumi et al., although the sample number was small, PET/CT appeared to be more useful than CT for evaluating the internal mammary and mediastinal lymph nodes because the smaller lymph nodes sometimes produced equivocal or negative CT findings (7) (Fig. 4).


The role of PET/CT for evaluating breast cancer.

Yang SK, Cho N, Moon WK - Korean J Radiol (2007 Sep-Oct)

Mediastinal lymph node metastasis in a 41-year-old woman who had undergone left modified radical mastectomy 10 months previously.A. The PET image shows multiple areas of increased uptake (arrows) in the left upper chest.B. The CT image shows a small soft tissue density in the anterior mediastinum (arrow).C. The PET/CT image shows co-registration of the FDG uptake and the soft tissue density in the anterior mediastinum, suggesting internal mammary lymph node metastases (arrow).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2626817&req=5

Figure 4: Mediastinal lymph node metastasis in a 41-year-old woman who had undergone left modified radical mastectomy 10 months previously.A. The PET image shows multiple areas of increased uptake (arrows) in the left upper chest.B. The CT image shows a small soft tissue density in the anterior mediastinum (arrow).C. The PET/CT image shows co-registration of the FDG uptake and the soft tissue density in the anterior mediastinum, suggesting internal mammary lymph node metastases (arrow).
Mentions: The metastasis to the internal mammary or mediastinal lymph nodes in breast cancer patients is often clinically occult. The prevalence of abnormal findings for the internal mammary or mediastinal lymph nodes by PET was about twice than of conventional CT in those patients with recurrent or metastatic breast cancer (15). In a study by Tatsumi et al., although the sample number was small, PET/CT appeared to be more useful than CT for evaluating the internal mammary and mediastinal lymph nodes because the smaller lymph nodes sometimes produced equivocal or negative CT findings (7) (Fig. 4).

Bottom Line: Positron emission tomography combined with computed tomography (PET/CT) has been receiving increasing attention during the recent years for making the diagnosis, for determining the staging and for the follow-up of various malignancies.The PET/CT findings of 58 breast cancer patients (age range: 34-79 years old, mean age: 50 years) were retrospectively compared with the PET or CT scans alone.PET/CT was found to be better than PET or CT alone for detecting small tumors or multiple metastases, for accurately localizing lymph node metastasis and for monitoring the response to chemotherapy in breast cancer patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, College of Medicine Seoul National University and The Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea.

ABSTRACT
Positron emission tomography combined with computed tomography (PET/CT) has been receiving increasing attention during the recent years for making the diagnosis, for determining the staging and for the follow-up of various malignancies. The PET/CT findings of 58 breast cancer patients (age range: 34-79 years old, mean age: 50 years) were retrospectively compared with the PET or CT scans alone. PET/CT was found to be better than PET or CT alone for detecting small tumors or multiple metastases, for accurately localizing lymph node metastasis and for monitoring the response to chemotherapy in breast cancer patients.

Show MeSH
Related in: MedlinePlus