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Variable CT findings of epithelial origin ovarian carcinoma according to the degree of histologic differentiation.

Jang YJ, Kim JK, Park SB, Cho KS - Korean J Radiol (2007 Mar-Apr)

Bottom Line: Bilateral ovarian involvement was more common in the poorly (48%) and moderately (42%) differentiated carcinomas than in the well differentiated carcinomas (7%) (p < 0.05).The frequency of a predominantly solid or solid nature was greater in the moderately and poorly differentiated carcinomas than in the well differentiated carcinomas (p < 0.0001).Epithelial origin ovarian carcinoma shows different CT findings according to the degree of histologic differentiation.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-Gu, Seoul, Korea.

ABSTRACT

Objective: We wanted to evaluate the CT findings of epithelial origin ovarian carcinoma according to the degree of histologic differentiation.

Materials and methods: This study enrolled 124 patients with 31 well differentiated, 44 moderately differentiated and 95 poorly differentiated carcinomas with epithelial origin. The CT images were retrospectively evaluated with regard to bilateral ovarian involvement, the tumor's nature, lymphadenopathy, adjacent organ invasion, peritoneal tumor seeding, a large amount of ascites and distant metastasis. In cystic, predominantly cystic and mixed tumors, the tumor wall, septa, papillary projection and necrosis in the solid portion were assessed.

Results: Bilateral ovarian involvement was more common in the poorly (48%) and moderately (42%) differentiated carcinomas than in the well differentiated carcinomas (7%) (p < 0.05). The frequency of a predominantly solid or solid nature was greater in the moderately and poorly differentiated carcinomas than in the well differentiated carcinomas (p < 0.0001). In the 87 tumors with a cystic, predominantly cystic or mixed nature, septa greater than 3 mm, papillary projection and necrosis in the solid portion were more common in the poorly differentiated carcinoma (91%, 91% and 77%, respectively) than in the moderately (64%, 68% and 34%, respectively) and well differentiated carcinomas (63%, 47% and 27%, respectively) (p < 0.05). Lymphadenopathy, organ invasion, tumor seeding and a large amount of ascites were more common in the poorly differentiated carcinomas (38%, 27%, 73% and 69%, respectively) than in the moderately (13%, 10%, 48% and 45%, respectively) and well differentiated carcinomas (3%, 0%, 10% and 17%, respectively) (p < 0.05).

Conclusion: Epithelial origin ovarian carcinoma shows different CT findings according to the degree of histologic differentiation.

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Related in: MedlinePlus

30-year-old female patient with well differentiated ovarian carcinoma. Transverse CT image shows 12-cm-sized unilocular cystic mass (arrows). Mass originates from the right ovary and the left ovary (not shown) is normal.
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Figure 1: 30-year-old female patient with well differentiated ovarian carcinoma. Transverse CT image shows 12-cm-sized unilocular cystic mass (arrows). Mass originates from the right ovary and the left ovary (not shown) is normal.

Mentions: Among 124 patients, 46 patients had bilateral ovarian involvement. Only two (7%) of the 29 patients with well differentiated carcinoma had bilateral ovarian involvement, whereas 13 (42%) of the 31 patients with moderately differentiated carcinoma and 31 (48%) of the 64 patients with poorly differentiated ovarian carcinoma showed bilateral ovarian involvement. The frequency of bilateral ovarian involvement was greater in the moderately and poorly differentiated carcinomas than in the well differentiated carcinomas (p = 0.002 and p < 0.0001, respectively), whereas the frequency was not significantly different between moderately and poorly differentiated carcinomas (p = 0.662) (Figs. 1, 2).


Variable CT findings of epithelial origin ovarian carcinoma according to the degree of histologic differentiation.

Jang YJ, Kim JK, Park SB, Cho KS - Korean J Radiol (2007 Mar-Apr)

30-year-old female patient with well differentiated ovarian carcinoma. Transverse CT image shows 12-cm-sized unilocular cystic mass (arrows). Mass originates from the right ovary and the left ovary (not shown) is normal.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2626777&req=5

Figure 1: 30-year-old female patient with well differentiated ovarian carcinoma. Transverse CT image shows 12-cm-sized unilocular cystic mass (arrows). Mass originates from the right ovary and the left ovary (not shown) is normal.
Mentions: Among 124 patients, 46 patients had bilateral ovarian involvement. Only two (7%) of the 29 patients with well differentiated carcinoma had bilateral ovarian involvement, whereas 13 (42%) of the 31 patients with moderately differentiated carcinoma and 31 (48%) of the 64 patients with poorly differentiated ovarian carcinoma showed bilateral ovarian involvement. The frequency of bilateral ovarian involvement was greater in the moderately and poorly differentiated carcinomas than in the well differentiated carcinomas (p = 0.002 and p < 0.0001, respectively), whereas the frequency was not significantly different between moderately and poorly differentiated carcinomas (p = 0.662) (Figs. 1, 2).

Bottom Line: Bilateral ovarian involvement was more common in the poorly (48%) and moderately (42%) differentiated carcinomas than in the well differentiated carcinomas (7%) (p < 0.05).The frequency of a predominantly solid or solid nature was greater in the moderately and poorly differentiated carcinomas than in the well differentiated carcinomas (p < 0.0001).Epithelial origin ovarian carcinoma shows different CT findings according to the degree of histologic differentiation.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-Gu, Seoul, Korea.

ABSTRACT

Objective: We wanted to evaluate the CT findings of epithelial origin ovarian carcinoma according to the degree of histologic differentiation.

Materials and methods: This study enrolled 124 patients with 31 well differentiated, 44 moderately differentiated and 95 poorly differentiated carcinomas with epithelial origin. The CT images were retrospectively evaluated with regard to bilateral ovarian involvement, the tumor's nature, lymphadenopathy, adjacent organ invasion, peritoneal tumor seeding, a large amount of ascites and distant metastasis. In cystic, predominantly cystic and mixed tumors, the tumor wall, septa, papillary projection and necrosis in the solid portion were assessed.

Results: Bilateral ovarian involvement was more common in the poorly (48%) and moderately (42%) differentiated carcinomas than in the well differentiated carcinomas (7%) (p < 0.05). The frequency of a predominantly solid or solid nature was greater in the moderately and poorly differentiated carcinomas than in the well differentiated carcinomas (p < 0.0001). In the 87 tumors with a cystic, predominantly cystic or mixed nature, septa greater than 3 mm, papillary projection and necrosis in the solid portion were more common in the poorly differentiated carcinoma (91%, 91% and 77%, respectively) than in the moderately (64%, 68% and 34%, respectively) and well differentiated carcinomas (63%, 47% and 27%, respectively) (p < 0.05). Lymphadenopathy, organ invasion, tumor seeding and a large amount of ascites were more common in the poorly differentiated carcinomas (38%, 27%, 73% and 69%, respectively) than in the moderately (13%, 10%, 48% and 45%, respectively) and well differentiated carcinomas (3%, 0%, 10% and 17%, respectively) (p < 0.05).

Conclusion: Epithelial origin ovarian carcinoma shows different CT findings according to the degree of histologic differentiation.

Show MeSH
Related in: MedlinePlus