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Pure and mixed tubular carcinoma of the breast: mammographic and sonographic differential features.

Shin HJ, Kim HH, Kim SM, Kim DB, Lee YR, Kim MJ, Gong G - Korean J Radiol (2007 Mar-Apr)

Bottom Line: When the lesions were detected mammographically, an irregularly shaped mass with a spiculated margin was more frequently found in the MT than in the PT (100% vs. 83%, respectively, p = 0.353).Surrounding tissue changes and posterior shadowing were more frequently found in the MT than in the PT (75% vs. 50%, respectively, p = 0.253, 58% vs. 19%, respectively, p = 1.000).An oval shaped mass was more frequently found in the PT than in the MT (44% vs. 25%, respectively; p = 0.434).

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-Gu, Seoul, Korea.

ABSTRACT

Objective: We wanted to evaluate the mammographic and sonographic differential features between pure (PT) and mixed tubular carcinoma (MT) of the breast.

Materials and methods: Between January 1998 and May 2004, 17 PTs and 14 MTs were pathologically confirmed at our institution. The preoperative mammography (n = 26) and sonography (n = 28) were analyzed by three radiologists according to BI-RADS.

Results: On mammography, a mass was not detected in eight patients with PT and in one patient with MT (57% vs. 8%, respectively, p = 0.021), which was statistically different. The other findings on mammography and sonography showed no statistical differences between the PT and MT, although the numerical values were different. When the lesions were detected mammographically, an irregularly shaped mass with a spiculated margin was more frequently found in the MT than in the PT (100% vs. 83%, respectively, p = 0.353). On sonography, all 28 patients presented with a mass and most lesions showed as not being circumscribed, hypoechoic masses with an echogenic halo. Surrounding tissue changes and posterior shadowing were more frequently found in the MT than in the PT (75% vs. 50%, respectively, p = 0.253, 58% vs. 19%, respectively, p = 1.000). An oval shaped mass was more frequently found in the PT than in the MT (44% vs. 25%, respectively; p = 0.434).

Conclusion: PT and MT cannot be precisely differentiated on mammography and sonography. However, the absence of a mass on mammography or the presence of an oval shaped mass would favor the diagnosis of PT. An irregularly shaped mass with surrounding tissue change and posterior shadowing on sonography would favor the diagnosis of MT and also a less favorable prognosis.

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A 41-year-old woman with pure tubular carcinoma (95% tubular component) with painful palpable lump in the upper outer quadrant of the right breast.A. Mammography shows an about 1.5-cm sized oval shaped isodense mass with an obscured margin (arrows) in the upper outer quadrant of the right breast.B. Sonography shows an about 1.2-cm sized oval shaped hypoechoic mass with a microlobulated margin (arrows) in the right breast.
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Figure 2: A 41-year-old woman with pure tubular carcinoma (95% tubular component) with painful palpable lump in the upper outer quadrant of the right breast.A. Mammography shows an about 1.5-cm sized oval shaped isodense mass with an obscured margin (arrows) in the upper outer quadrant of the right breast.B. Sonography shows an about 1.2-cm sized oval shaped hypoechoic mass with a microlobulated margin (arrows) in the right breast.

Mentions: Mammographically, both the PT and MT presented as a mass in 17 patients, and these masses were located in the upper outer quadrant (n = 7), the upper portion (n = 5), the upper inner quadrant (n = 3), the outer portion (n = 1), and the lower outer quadrant (n = 1). These masses commonly showed an irregular shape (16/17, 94%) and a spiculated margin (16/17, 94%). An oval shaped mass with an obscured margin was found in only one patient with PT (Fig. 2A). An irregularly shaped mass with a spiculated margin was more frequently found in the MT than in the PT (11/11, 100% vs. 5/6, 83%, respectively, p = 0.353), but no statistical significant difference was found for the mass shape or the margin between the two groups. A long spiculated margin for which the length of the spicule was longer than the longest diameter of the mass was more frequently found in the MT (Fig. 3A) than in the PT (7/11, 64% vs. 2/5, 40%, respectively, p = 0.596). Benign calcifications were found in only two patients with MT (Figs. 3A, B).


Pure and mixed tubular carcinoma of the breast: mammographic and sonographic differential features.

Shin HJ, Kim HH, Kim SM, Kim DB, Lee YR, Kim MJ, Gong G - Korean J Radiol (2007 Mar-Apr)

A 41-year-old woman with pure tubular carcinoma (95% tubular component) with painful palpable lump in the upper outer quadrant of the right breast.A. Mammography shows an about 1.5-cm sized oval shaped isodense mass with an obscured margin (arrows) in the upper outer quadrant of the right breast.B. Sonography shows an about 1.2-cm sized oval shaped hypoechoic mass with a microlobulated margin (arrows) in the right breast.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2626773&req=5

Figure 2: A 41-year-old woman with pure tubular carcinoma (95% tubular component) with painful palpable lump in the upper outer quadrant of the right breast.A. Mammography shows an about 1.5-cm sized oval shaped isodense mass with an obscured margin (arrows) in the upper outer quadrant of the right breast.B. Sonography shows an about 1.2-cm sized oval shaped hypoechoic mass with a microlobulated margin (arrows) in the right breast.
Mentions: Mammographically, both the PT and MT presented as a mass in 17 patients, and these masses were located in the upper outer quadrant (n = 7), the upper portion (n = 5), the upper inner quadrant (n = 3), the outer portion (n = 1), and the lower outer quadrant (n = 1). These masses commonly showed an irregular shape (16/17, 94%) and a spiculated margin (16/17, 94%). An oval shaped mass with an obscured margin was found in only one patient with PT (Fig. 2A). An irregularly shaped mass with a spiculated margin was more frequently found in the MT than in the PT (11/11, 100% vs. 5/6, 83%, respectively, p = 0.353), but no statistical significant difference was found for the mass shape or the margin between the two groups. A long spiculated margin for which the length of the spicule was longer than the longest diameter of the mass was more frequently found in the MT (Fig. 3A) than in the PT (7/11, 64% vs. 2/5, 40%, respectively, p = 0.596). Benign calcifications were found in only two patients with MT (Figs. 3A, B).

Bottom Line: When the lesions were detected mammographically, an irregularly shaped mass with a spiculated margin was more frequently found in the MT than in the PT (100% vs. 83%, respectively, p = 0.353).Surrounding tissue changes and posterior shadowing were more frequently found in the MT than in the PT (75% vs. 50%, respectively, p = 0.253, 58% vs. 19%, respectively, p = 1.000).An oval shaped mass was more frequently found in the PT than in the MT (44% vs. 25%, respectively; p = 0.434).

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-Gu, Seoul, Korea.

ABSTRACT

Objective: We wanted to evaluate the mammographic and sonographic differential features between pure (PT) and mixed tubular carcinoma (MT) of the breast.

Materials and methods: Between January 1998 and May 2004, 17 PTs and 14 MTs were pathologically confirmed at our institution. The preoperative mammography (n = 26) and sonography (n = 28) were analyzed by three radiologists according to BI-RADS.

Results: On mammography, a mass was not detected in eight patients with PT and in one patient with MT (57% vs. 8%, respectively, p = 0.021), which was statistically different. The other findings on mammography and sonography showed no statistical differences between the PT and MT, although the numerical values were different. When the lesions were detected mammographically, an irregularly shaped mass with a spiculated margin was more frequently found in the MT than in the PT (100% vs. 83%, respectively, p = 0.353). On sonography, all 28 patients presented with a mass and most lesions showed as not being circumscribed, hypoechoic masses with an echogenic halo. Surrounding tissue changes and posterior shadowing were more frequently found in the MT than in the PT (75% vs. 50%, respectively, p = 0.253, 58% vs. 19%, respectively, p = 1.000). An oval shaped mass was more frequently found in the PT than in the MT (44% vs. 25%, respectively; p = 0.434).

Conclusion: PT and MT cannot be precisely differentiated on mammography and sonography. However, the absence of a mass on mammography or the presence of an oval shaped mass would favor the diagnosis of PT. An irregularly shaped mass with surrounding tissue change and posterior shadowing on sonography would favor the diagnosis of MT and also a less favorable prognosis.

Show MeSH
Related in: MedlinePlus