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Sex cord-gonadal stromal tumor of the rete testis.

Sajadi KP, Dalton RR, Brown JA - Adv Urol (2008)

Bottom Line: A 34-year-old tetraplegic patient with suppurative epididymitis was found on follow-up examination and ultrasonography to have a testicular mass.Testicular sex cord-stromal tumors are far less common than germ cell neoplasms and are usually benign.This undifferentiated sex cord-stromal tumor, occurring in a previously unreported location, is an example of an unusual lesion mimicking an intratesticular malignant neoplasm.

View Article: PubMed Central - PubMed

Affiliation: Section of Urology, Department of Surgery, Medical College of Georgia, Augusta, GA 30912, USA. ksajadi@mcg.edu

ABSTRACT
A 34-year-old tetraplegic patient with suppurative epididymitis was found on follow-up examination and ultrasonography to have a testicular mass. The radical orchiectomy specimen contained an undifferentiated spindled sex cord-stromal tumor arising in the rete testis. Testicular sex cord-stromal tumors are far less common than germ cell neoplasms and are usually benign. The close relationship between sex cords and ductules of the rete testis during development provides the opportunity for these uncommon tumors to arise anatomically within the rete tesis. This undifferentiated sex cord-stromal tumor, occurring in a previously unreported location, is an example of an unusual lesion mimicking an intratesticular malignant neoplasm.

No MeSH data available.


Related in: MedlinePlus

(a) Closer view of gross specimendemonstrating discrete white nodule which was firm. (b) A spindle cellproliferation was intimately associated with unremarkable ductules within therete testis. (c) Higher power viewillustrating bland spindled cell proliferation without mitotic activity.
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fig3: (a) Closer view of gross specimendemonstrating discrete white nodule which was firm. (b) A spindle cellproliferation was intimately associated with unremarkable ductules within therete testis. (c) Higher power viewillustrating bland spindled cell proliferation without mitotic activity.

Mentions: Microscopicexamination (Figure 3, upper right and lower panels) revealed the nodule to becomprised of a well-demarcated, nodular proliferation of bland spindle cellswithin the mediastinum testis. No areas of tubule or cyst formation were identified. Thespindle cells surrounded unremarkable ductules of the rete testis. Neithermitotic activity nor necrosis was present. Immunohistochemical stains for placental alkalinephosphatase (PLAP), CD30, hCG, AFP, CD99, and caldesmon were negative. Thespindled cells were positive for vimentin, S-100, WT-1, and focally positivefor inhibin and pancytokeratin. Also present were acute and chronicinflammation of the epididymis.


Sex cord-gonadal stromal tumor of the rete testis.

Sajadi KP, Dalton RR, Brown JA - Adv Urol (2008)

(a) Closer view of gross specimendemonstrating discrete white nodule which was firm. (b) A spindle cellproliferation was intimately associated with unremarkable ductules within therete testis. (c) Higher power viewillustrating bland spindled cell proliferation without mitotic activity.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2612754&req=5

fig3: (a) Closer view of gross specimendemonstrating discrete white nodule which was firm. (b) A spindle cellproliferation was intimately associated with unremarkable ductules within therete testis. (c) Higher power viewillustrating bland spindled cell proliferation without mitotic activity.
Mentions: Microscopicexamination (Figure 3, upper right and lower panels) revealed the nodule to becomprised of a well-demarcated, nodular proliferation of bland spindle cellswithin the mediastinum testis. No areas of tubule or cyst formation were identified. Thespindle cells surrounded unremarkable ductules of the rete testis. Neithermitotic activity nor necrosis was present. Immunohistochemical stains for placental alkalinephosphatase (PLAP), CD30, hCG, AFP, CD99, and caldesmon were negative. Thespindled cells were positive for vimentin, S-100, WT-1, and focally positivefor inhibin and pancytokeratin. Also present were acute and chronicinflammation of the epididymis.

Bottom Line: A 34-year-old tetraplegic patient with suppurative epididymitis was found on follow-up examination and ultrasonography to have a testicular mass.Testicular sex cord-stromal tumors are far less common than germ cell neoplasms and are usually benign.This undifferentiated sex cord-stromal tumor, occurring in a previously unreported location, is an example of an unusual lesion mimicking an intratesticular malignant neoplasm.

View Article: PubMed Central - PubMed

Affiliation: Section of Urology, Department of Surgery, Medical College of Georgia, Augusta, GA 30912, USA. ksajadi@mcg.edu

ABSTRACT
A 34-year-old tetraplegic patient with suppurative epididymitis was found on follow-up examination and ultrasonography to have a testicular mass. The radical orchiectomy specimen contained an undifferentiated spindled sex cord-stromal tumor arising in the rete testis. Testicular sex cord-stromal tumors are far less common than germ cell neoplasms and are usually benign. The close relationship between sex cords and ductules of the rete testis during development provides the opportunity for these uncommon tumors to arise anatomically within the rete tesis. This undifferentiated sex cord-stromal tumor, occurring in a previously unreported location, is an example of an unusual lesion mimicking an intratesticular malignant neoplasm.

No MeSH data available.


Related in: MedlinePlus