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Nitrous oxide sedation and bispectral index.

Işik B, Tüzüner T, Tezkirecioglu M, Oztaş N - Eur J Dent (2007)

Bottom Line: Mean age and weight of the children were 9.5 +/- 1.4 years and 23.7 +/- 9.7 kg, respectively.Nitrous oxide inhalation produced no changes in BIS levels despite a sedation level in OAA/S scores were observed at 40-60% N(2)O concentrations.BIS values do not change during N(2)O/O(2) sedation and the BIS monitor is not appropriate to evaluate the depth of sedation provided by N(2)O/O(2) during primary teeth extraction in children.

View Article: PubMed Central - PubMed

Affiliation: Anesthesiology and Reanimation Specialist, Gazi University, Faculty of Dentistry, Department Oral and Maxillofacial Surgery, Ankara, TURKEY.

ABSTRACT

Objectives: To determine whether bispectral analysis (BIS) changes during nitrous oxide (N(2)O) sedation in anxious children undergoing extraction of primary teeth.

Methods: In this prospective study 45, ASA physical status I children, aged between 7 to 12 years and scheduled for primary teeth extraction under N(2)O/O(2) sedation are included. At baseline (T0) and during the sedation procedure (T1-6); BIS levels, Ramsay Sedation Scores (RSS), oxygen saturation (Sp0(2)), and heart rate (HR) were recorded at one-minute intervals. Forty percent N(2)O in O(2) was given by a nasal hood, and N(2)O concentration was enhanced to 60% in a two-minute period. Paired measurements of BIS levels with Observer's Assessment of Alertness and Sedation (OAA/S) scores were obtained during sedation procedure.

Results: Since 5 patients refused application of the nasal hood, a total 40 of the original 45 subjects completed the study. Mean age and weight of the children were 9.5 +/- 1.4 years and 23.7 +/- 9.7 kg, respectively. Nitrous oxide inhalation produced no changes in BIS levels despite a sedation level in OAA/S scores were observed at 40-60% N(2)O concentrations.

Conclusions: BIS values do not change during N(2)O/O(2) sedation and the BIS monitor is not appropriate to evaluate the depth of sedation provided by N(2)O/O(2) during primary teeth extraction in children.

No MeSH data available.


Correlation legend between Bispectral Index (BIS) levels and Observer’s Assessment of Alertness/Sedation (OAA/S) scores.Pearson Correlation Coefficient (r) value: r =0–0.25 weak correlation
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f1-0010240: Correlation legend between Bispectral Index (BIS) levels and Observer’s Assessment of Alertness/Sedation (OAA/S) scores.Pearson Correlation Coefficient (r) value: r =0–0.25 weak correlation

Mentions: The comparison of time dependent mean BIS values at T1, T2, T3, T4, T5 and T6 time points between T0 sessions were similar and statistically not different (P > .05). The mean value of BIS was 97.4. Before N2O/O2 sedation, patients’ RSS were determined as 1 but after the administration of N2O/O2, at the T1-6 time points patients’ RSS were 2 and OAA/S scores of patients’ were 4 or 5. During T1-6 time points all patients (n=40) were relax and not reject the extractions. Although administration of 40–60% N2O concentration is enough to provide sedation according to the OAA/S scores in 40 children during the study period, no changes were obtained in BIS values. No correlation was found between BIS and the OAA/S scores levels at the T1-6 periods (P = .126, r = 0.1). Ramsay Sedation Scores and OAA/S correlations cannot be computed because at least one of the variables is constant. Figure 1 shows all the Pearson correlation coefficients between BIS levels and OAA/S scores during the study period. Pearson coefficient values indicate that weak correlation was obtained between BIS levels and OAA/S scores at all time periods (r < 0.25). There was no complication except nausea and vomiting at two patients during the recovery period.


Nitrous oxide sedation and bispectral index.

Işik B, Tüzüner T, Tezkirecioglu M, Oztaş N - Eur J Dent (2007)

Correlation legend between Bispectral Index (BIS) levels and Observer’s Assessment of Alertness/Sedation (OAA/S) scores.Pearson Correlation Coefficient (r) value: r =0–0.25 weak correlation
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2609910&req=5

f1-0010240: Correlation legend between Bispectral Index (BIS) levels and Observer’s Assessment of Alertness/Sedation (OAA/S) scores.Pearson Correlation Coefficient (r) value: r =0–0.25 weak correlation
Mentions: The comparison of time dependent mean BIS values at T1, T2, T3, T4, T5 and T6 time points between T0 sessions were similar and statistically not different (P > .05). The mean value of BIS was 97.4. Before N2O/O2 sedation, patients’ RSS were determined as 1 but after the administration of N2O/O2, at the T1-6 time points patients’ RSS were 2 and OAA/S scores of patients’ were 4 or 5. During T1-6 time points all patients (n=40) were relax and not reject the extractions. Although administration of 40–60% N2O concentration is enough to provide sedation according to the OAA/S scores in 40 children during the study period, no changes were obtained in BIS values. No correlation was found between BIS and the OAA/S scores levels at the T1-6 periods (P = .126, r = 0.1). Ramsay Sedation Scores and OAA/S correlations cannot be computed because at least one of the variables is constant. Figure 1 shows all the Pearson correlation coefficients between BIS levels and OAA/S scores during the study period. Pearson coefficient values indicate that weak correlation was obtained between BIS levels and OAA/S scores at all time periods (r < 0.25). There was no complication except nausea and vomiting at two patients during the recovery period.

Bottom Line: Mean age and weight of the children were 9.5 +/- 1.4 years and 23.7 +/- 9.7 kg, respectively.Nitrous oxide inhalation produced no changes in BIS levels despite a sedation level in OAA/S scores were observed at 40-60% N(2)O concentrations.BIS values do not change during N(2)O/O(2) sedation and the BIS monitor is not appropriate to evaluate the depth of sedation provided by N(2)O/O(2) during primary teeth extraction in children.

View Article: PubMed Central - PubMed

Affiliation: Anesthesiology and Reanimation Specialist, Gazi University, Faculty of Dentistry, Department Oral and Maxillofacial Surgery, Ankara, TURKEY.

ABSTRACT

Objectives: To determine whether bispectral analysis (BIS) changes during nitrous oxide (N(2)O) sedation in anxious children undergoing extraction of primary teeth.

Methods: In this prospective study 45, ASA physical status I children, aged between 7 to 12 years and scheduled for primary teeth extraction under N(2)O/O(2) sedation are included. At baseline (T0) and during the sedation procedure (T1-6); BIS levels, Ramsay Sedation Scores (RSS), oxygen saturation (Sp0(2)), and heart rate (HR) were recorded at one-minute intervals. Forty percent N(2)O in O(2) was given by a nasal hood, and N(2)O concentration was enhanced to 60% in a two-minute period. Paired measurements of BIS levels with Observer's Assessment of Alertness and Sedation (OAA/S) scores were obtained during sedation procedure.

Results: Since 5 patients refused application of the nasal hood, a total 40 of the original 45 subjects completed the study. Mean age and weight of the children were 9.5 +/- 1.4 years and 23.7 +/- 9.7 kg, respectively. Nitrous oxide inhalation produced no changes in BIS levels despite a sedation level in OAA/S scores were observed at 40-60% N(2)O concentrations.

Conclusions: BIS values do not change during N(2)O/O(2) sedation and the BIS monitor is not appropriate to evaluate the depth of sedation provided by N(2)O/O(2) during primary teeth extraction in children.

No MeSH data available.