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Control strategy for Echinococcus multilocularis.

Hegglin D, Deplazes P - Emerging Infect. Dis. (2008)

Bottom Line: Echinococcus multilocularis, the causative agent of zoonotic alveolar echinococcosis, can be controlled effectively by the experimental delivery of anthelminthic baits for urban foxes.Monthly baiting over a 45-month period was effective for long-lasting control.Trimonthly baiting intervals were far less effective and did not prevent parasite recovery.

View Article: PubMed Central - PubMed

Affiliation: Institute of Parasitology, University of Zurich, Zurich, Switzerland. dhegglin@access.uzh.ch

ABSTRACT
Echinococcus multilocularis, the causative agent of zoonotic alveolar echinococcosis, can be controlled effectively by the experimental delivery of anthelminthic baits for urban foxes. Monthly baiting over a 45-month period was effective for long-lasting control. Trimonthly baiting intervals were far less effective and did not prevent parasite recovery.

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Related in: MedlinePlus

Contamination with Echinococcus multilocularis shown in study plots. Portion of coproantigen-positive (by ELISA) fox feces in study plots with 5 different treatment schemes (see Figure 1). Gray outlined boxes and error bars represent the 95% confidence intervals of ELISA-positive feces during the 4 sampling periods. Treatment schemes: co/co, control/control; b1/b3, monthly/trimonthly baiting; co/b3, control/trimonthly baiting; b1/co, monthly baiting/control; and b1/b1,monthly baiting/monthly baiting.
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Figure 2: Contamination with Echinococcus multilocularis shown in study plots. Portion of coproantigen-positive (by ELISA) fox feces in study plots with 5 different treatment schemes (see Figure 1). Gray outlined boxes and error bars represent the 95% confidence intervals of ELISA-positive feces during the 4 sampling periods. Treatment schemes: co/co, control/control; b1/b3, monthly/trimonthly baiting; co/b3, control/trimonthly baiting; b1/co, monthly baiting/control; and b1/b1,monthly baiting/monthly baiting.

Mentions: The proportion of coproantigen-positive feces detected by ELISA (hereafter referred to as E. multilocularis contamination) showed no significant statistical variation in the three 1-km2 plots that were never baited and averaged 26.5% contamination (Figure 2). In the 6 areas that were baited at monthly intervals during the first phase, E. multilocularis contamination decreased significantly from sampling period 1 (b1/b3 plots: 22.2%, 95% confidence interval [CI] 11.2%–37.1%; b1/co plots: 37.7%, CI 26.3%–50.2%) to sampling period 2 (b1/b3 plots: 5.4%, CI 2.4%–10.4%; b1/co plots: 5.6%, CI 2.3%–11.2%) (Figure 2). After reassigning 3 monthly baited plots to control plots (b1/co plots), a significant rise of E.multilocularis contamination was detected to 30.2% (CI 24.9%–36.0%). Also, the change from a monthly baiting interval to a trimonthly interval (b1/b3 plots) resulted in a significant increase to 19.5% (CI 15.2%–24.4%), whereas the trimonthly bait delivery in the co/b3 plots led to a significant decrease from 30.4% (CI 22.9%–38.8%) to 17.6% (CI 13.3%–22.5%).


Control strategy for Echinococcus multilocularis.

Hegglin D, Deplazes P - Emerging Infect. Dis. (2008)

Contamination with Echinococcus multilocularis shown in study plots. Portion of coproantigen-positive (by ELISA) fox feces in study plots with 5 different treatment schemes (see Figure 1). Gray outlined boxes and error bars represent the 95% confidence intervals of ELISA-positive feces during the 4 sampling periods. Treatment schemes: co/co, control/control; b1/b3, monthly/trimonthly baiting; co/b3, control/trimonthly baiting; b1/co, monthly baiting/control; and b1/b1,monthly baiting/monthly baiting.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2609876&req=5

Figure 2: Contamination with Echinococcus multilocularis shown in study plots. Portion of coproantigen-positive (by ELISA) fox feces in study plots with 5 different treatment schemes (see Figure 1). Gray outlined boxes and error bars represent the 95% confidence intervals of ELISA-positive feces during the 4 sampling periods. Treatment schemes: co/co, control/control; b1/b3, monthly/trimonthly baiting; co/b3, control/trimonthly baiting; b1/co, monthly baiting/control; and b1/b1,monthly baiting/monthly baiting.
Mentions: The proportion of coproantigen-positive feces detected by ELISA (hereafter referred to as E. multilocularis contamination) showed no significant statistical variation in the three 1-km2 plots that were never baited and averaged 26.5% contamination (Figure 2). In the 6 areas that were baited at monthly intervals during the first phase, E. multilocularis contamination decreased significantly from sampling period 1 (b1/b3 plots: 22.2%, 95% confidence interval [CI] 11.2%–37.1%; b1/co plots: 37.7%, CI 26.3%–50.2%) to sampling period 2 (b1/b3 plots: 5.4%, CI 2.4%–10.4%; b1/co plots: 5.6%, CI 2.3%–11.2%) (Figure 2). After reassigning 3 monthly baited plots to control plots (b1/co plots), a significant rise of E.multilocularis contamination was detected to 30.2% (CI 24.9%–36.0%). Also, the change from a monthly baiting interval to a trimonthly interval (b1/b3 plots) resulted in a significant increase to 19.5% (CI 15.2%–24.4%), whereas the trimonthly bait delivery in the co/b3 plots led to a significant decrease from 30.4% (CI 22.9%–38.8%) to 17.6% (CI 13.3%–22.5%).

Bottom Line: Echinococcus multilocularis, the causative agent of zoonotic alveolar echinococcosis, can be controlled effectively by the experimental delivery of anthelminthic baits for urban foxes.Monthly baiting over a 45-month period was effective for long-lasting control.Trimonthly baiting intervals were far less effective and did not prevent parasite recovery.

View Article: PubMed Central - PubMed

Affiliation: Institute of Parasitology, University of Zurich, Zurich, Switzerland. dhegglin@access.uzh.ch

ABSTRACT
Echinococcus multilocularis, the causative agent of zoonotic alveolar echinococcosis, can be controlled effectively by the experimental delivery of anthelminthic baits for urban foxes. Monthly baiting over a 45-month period was effective for long-lasting control. Trimonthly baiting intervals were far less effective and did not prevent parasite recovery.

Show MeSH
Related in: MedlinePlus