Limits...
Cystoid macular oedema in Cogans syndrome-a case report.

Pherwani A, Bansal S, Agrawal S, Gillow T - Cases J (2008)

Bottom Line: He had cystoid macular edema which failed to respond initially to steroid, methotrexate and azothiaprine however resolved after treatment with mycophenolate mofetil.Recurrent cystoid macular oedema is a unique finding in this condition and can be difficult to control.Multidisciplinary management of this multisystem disorder is vital.

View Article: PubMed Central - HTML - PubMed

Affiliation: St James' University Hospital, Leeds, UK. shveta.ophth@gmail.com.

ABSTRACT

Introduction: Cogan's Syndrome is typically characterised by a non syphilitic interstitial keratitis (IK), with or without conjunctivitis, iritis or subconjunctival bleeding and progressive sensorineural hearing loss within two years of ocular signs. Atypical ocular manifestations include episcleritis, scleritis, posterior scleritis, retinal artery occlusion, choroiditis, retinal vasculitis, and optic disc oedema. We report a case of Cogan's syndrome in with recurrent cystoid macular oedema was the main feature.

Case presentation: A patient was diagnosed with Cogan's syndrome nearly 2 years after first presentation. He had cystoid macular edema which failed to respond initially to steroid, methotrexate and azothiaprine however resolved after treatment with mycophenolate mofetil.

Conclusion: Cogan's syndrome is rare and presents a challenge in terms of diagnosis and treatment. Recurrent cystoid macular oedema is a unique finding in this condition and can be difficult to control. Multidisciplinary management of this multisystem disorder is vital.

No MeSH data available.


Related in: MedlinePlus

Right cornea showing stromal opacity with vascularisation in the superior aspect.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC2602997&req=5

Figure 1: Right cornea showing stromal opacity with vascularisation in the superior aspect.

Mentions: Two years later the patient presented with blurred and distorted vision in both eyes. Aided Snellen's acuity was 6/9 bilaterally. The right cornea still had the deep stromal opacity with ghost vessels superiorly (fig 1). There was mild anterior uveitis. There was mild anterior uveitis and bilateral cystoid macular edema (CMO) (fig 2 and 3). Topical steroids and ketorolac were commenced. Blood tests revealed a raised ESR, serology for autoantibodies, Treponema and Borrelia, serum ACE, chest X ray were normal.


Cystoid macular oedema in Cogans syndrome-a case report.

Pherwani A, Bansal S, Agrawal S, Gillow T - Cases J (2008)

Right cornea showing stromal opacity with vascularisation in the superior aspect.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2602997&req=5

Figure 1: Right cornea showing stromal opacity with vascularisation in the superior aspect.
Mentions: Two years later the patient presented with blurred and distorted vision in both eyes. Aided Snellen's acuity was 6/9 bilaterally. The right cornea still had the deep stromal opacity with ghost vessels superiorly (fig 1). There was mild anterior uveitis. There was mild anterior uveitis and bilateral cystoid macular edema (CMO) (fig 2 and 3). Topical steroids and ketorolac were commenced. Blood tests revealed a raised ESR, serology for autoantibodies, Treponema and Borrelia, serum ACE, chest X ray were normal.

Bottom Line: He had cystoid macular edema which failed to respond initially to steroid, methotrexate and azothiaprine however resolved after treatment with mycophenolate mofetil.Recurrent cystoid macular oedema is a unique finding in this condition and can be difficult to control.Multidisciplinary management of this multisystem disorder is vital.

View Article: PubMed Central - HTML - PubMed

Affiliation: St James' University Hospital, Leeds, UK. shveta.ophth@gmail.com.

ABSTRACT

Introduction: Cogan's Syndrome is typically characterised by a non syphilitic interstitial keratitis (IK), with or without conjunctivitis, iritis or subconjunctival bleeding and progressive sensorineural hearing loss within two years of ocular signs. Atypical ocular manifestations include episcleritis, scleritis, posterior scleritis, retinal artery occlusion, choroiditis, retinal vasculitis, and optic disc oedema. We report a case of Cogan's syndrome in with recurrent cystoid macular oedema was the main feature.

Case presentation: A patient was diagnosed with Cogan's syndrome nearly 2 years after first presentation. He had cystoid macular edema which failed to respond initially to steroid, methotrexate and azothiaprine however resolved after treatment with mycophenolate mofetil.

Conclusion: Cogan's syndrome is rare and presents a challenge in terms of diagnosis and treatment. Recurrent cystoid macular oedema is a unique finding in this condition and can be difficult to control. Multidisciplinary management of this multisystem disorder is vital.

No MeSH data available.


Related in: MedlinePlus