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Rickettsia slovaca in Dermacentor marginatus and tick-borne lymphadenopathy, Tuscany, Italy.

Selmi M, Bertolotti L, Tomassone L, Mannelli A - Emerging Infect. Dis. (2008)

Bottom Line: Of 263 patients in Tuscany, Italy, from whom ticks were removed during July 2005-May 2007, five showed signs of tick-borne encephalopathy.Of the ticks, 17 were Dermacentor marginatus; 6 (35.3%) of these were identified by sequence analysis as containing Rickettsia slovaca.Tick-borne lympadenopathy occurs in this area.

View Article: PubMed Central - PubMed

Affiliation: Osservatorio Permanente per Patologie a Trasmissione Vettoriale, Lucca, Italy. m.selmi@usl2.toscana.it

ABSTRACT
Of 263 patients in Tuscany, Italy, from whom ticks were removed during July 2005-May 2007, five showed signs of tick-borne encephalopathy. Of the ticks, 17 were Dermacentor marginatus; 6 (35.3%) of these were identified by sequence analysis as containing Rickettsia slovaca. Tick-borne lympadenopathy occurs in this area.

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Related in: MedlinePlus

Enlarged lymph nodes (A), tache noire (arrowhead) (B), and alopecia (C) in patients admitted to the Lucca local health unit, Tuscany, Italy.
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Figure 2: Enlarged lymph nodes (A), tache noire (arrowhead) (B), and alopecia (C) in patients admitted to the Lucca local health unit, Tuscany, Italy.

Mentions: Five patients (29.4%) (2 adults and 3 children) showed clinical signs typically related to tick-borne lymphadenopathy. We defined tick-borne lymphadenopathy case-patients as those with skin lesion (eschar) at the tick bite site and regional lymphadenopathy (2). The 5 patients were examined by physicians at least twice. Each patient had enlarged lymph nodes (Figure 2 , panel A) at the second examination. Crusted scalp lesions (Figure 2, panel B) ranged in diameter from 8 mm to 25 mm. One patient was surgically treated to remove necrotic tissue from a large tache noire; he showed alopecia >8 months after acute episode (Figure 2, panel C). Three cases were recorded in spring, 1 in autumn, and 1 in winter (Table 2). Association between Dermacentor TEIs and occurrence of symptoms was not statistically significant (p = 0.13). Six (35.3%) of 17 ticks were positive by PCR for either gtlA or ompA. The ompA gene sequences of all positive samples showed similarity of 100% with the R. slovaca (GenBank accession no. U43808).


Rickettsia slovaca in Dermacentor marginatus and tick-borne lymphadenopathy, Tuscany, Italy.

Selmi M, Bertolotti L, Tomassone L, Mannelli A - Emerging Infect. Dis. (2008)

Enlarged lymph nodes (A), tache noire (arrowhead) (B), and alopecia (C) in patients admitted to the Lucca local health unit, Tuscany, Italy.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2600248&req=5

Figure 2: Enlarged lymph nodes (A), tache noire (arrowhead) (B), and alopecia (C) in patients admitted to the Lucca local health unit, Tuscany, Italy.
Mentions: Five patients (29.4%) (2 adults and 3 children) showed clinical signs typically related to tick-borne lymphadenopathy. We defined tick-borne lymphadenopathy case-patients as those with skin lesion (eschar) at the tick bite site and regional lymphadenopathy (2). The 5 patients were examined by physicians at least twice. Each patient had enlarged lymph nodes (Figure 2 , panel A) at the second examination. Crusted scalp lesions (Figure 2, panel B) ranged in diameter from 8 mm to 25 mm. One patient was surgically treated to remove necrotic tissue from a large tache noire; he showed alopecia >8 months after acute episode (Figure 2, panel C). Three cases were recorded in spring, 1 in autumn, and 1 in winter (Table 2). Association between Dermacentor TEIs and occurrence of symptoms was not statistically significant (p = 0.13). Six (35.3%) of 17 ticks were positive by PCR for either gtlA or ompA. The ompA gene sequences of all positive samples showed similarity of 100% with the R. slovaca (GenBank accession no. U43808).

Bottom Line: Of 263 patients in Tuscany, Italy, from whom ticks were removed during July 2005-May 2007, five showed signs of tick-borne encephalopathy.Of the ticks, 17 were Dermacentor marginatus; 6 (35.3%) of these were identified by sequence analysis as containing Rickettsia slovaca.Tick-borne lympadenopathy occurs in this area.

View Article: PubMed Central - PubMed

Affiliation: Osservatorio Permanente per Patologie a Trasmissione Vettoriale, Lucca, Italy. m.selmi@usl2.toscana.it

ABSTRACT
Of 263 patients in Tuscany, Italy, from whom ticks were removed during July 2005-May 2007, five showed signs of tick-borne encephalopathy. Of the ticks, 17 were Dermacentor marginatus; 6 (35.3%) of these were identified by sequence analysis as containing Rickettsia slovaca. Tick-borne lympadenopathy occurs in this area.

Show MeSH
Related in: MedlinePlus