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Outbreak of Puumala virus infection, Sweden.

Pettersson L, Boman J, Juto P, Evander M, Ahlm C - Emerging Infect. Dis. (2008)

Bottom Line: An unexpected and large outbreak of Puumala virus infection in Sweden resulted in 313 nephropathia epidemica patients/100,000 persons in Västerbotten County during 2007.An increase in the rodent population, milder weather, and less snow cover probably contributed to the outbreak.

View Article: PubMed Central - PubMed

Affiliation: Umeå University, Umeå, Sweden.

ABSTRACT
An unexpected and large outbreak of Puumala virus infection in Sweden resulted in 313 nephropathia epidemica patients/100,000 persons in Västerbotten County during 2007. An increase in the rodent population, milder weather, and less snow cover probably contributed to the outbreak.

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Climate conditions, December 1998–2006, in the nephropathia epidemica outbreak area of Västerbotten County, Sweden. A) Number of days with a snow cover. B) Average temperature. Snow cover was defined as a snow depth >0 cm. Measurements were made in locations ≈30 km from the coast. Data were obtained from the Swedish Meteorological and Hydrological Institute.
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Figure 2: Climate conditions, December 1998–2006, in the nephropathia epidemica outbreak area of Västerbotten County, Sweden. A) Number of days with a snow cover. B) Average temperature. Snow cover was defined as a snow depth >0 cm. Measurements were made in locations ≈30 km from the coast. Data were obtained from the Swedish Meteorological and Hydrological Institute.

Mentions: We considered other possible factors influencing hantavirus transmission to humans. One factor is increased exposure of humans to infected rodent excreta. We had received several reports from inhabitants in areas where bank voles normally live that more bank voles were found in traps inside houses than usual. When we investigated the weather conditions during this period, December 2006 was exceptional with respect to the mild weather with no or little snow and hard ice cover in the coastal area of northern Sweden. In Västerbotten County, the average temperature in December was 6.0°C–9.0°C warmer than normal (normally the average temperature in Västerbotten County varies by –4°C along the coast and –13°C in the mountains) The average temperature in Sweden was 4.5°C–9.5°C warmer than normal in December 2006 (Figure 2). The snow cover during winter is important for bank vole survival because bank voles have access to food below the snow and hide from predators and the cold (10). During 2 previous NE peak periods (2001–2002 and 2004–2005), the ground was already covered with snow in early winter (Figure 2). For these reasons, during December 2006, when the ground had no snow cover for 25 of 31 days (Figure 2), bank voles may have sought refuge in barns and houses and other buildings, thereby increasing the exposure for the human population at risk. A concurrent epizootic may have occurred among bank voles, which resulted in larger numbers of infectious animals, as shown in previous rodent studies (11,12). However, we did not have access to rodents during this period and this hypothesis needs to be studied.


Outbreak of Puumala virus infection, Sweden.

Pettersson L, Boman J, Juto P, Evander M, Ahlm C - Emerging Infect. Dis. (2008)

Climate conditions, December 1998–2006, in the nephropathia epidemica outbreak area of Västerbotten County, Sweden. A) Number of days with a snow cover. B) Average temperature. Snow cover was defined as a snow depth >0 cm. Measurements were made in locations ≈30 km from the coast. Data were obtained from the Swedish Meteorological and Hydrological Institute.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2600231&req=5

Figure 2: Climate conditions, December 1998–2006, in the nephropathia epidemica outbreak area of Västerbotten County, Sweden. A) Number of days with a snow cover. B) Average temperature. Snow cover was defined as a snow depth >0 cm. Measurements were made in locations ≈30 km from the coast. Data were obtained from the Swedish Meteorological and Hydrological Institute.
Mentions: We considered other possible factors influencing hantavirus transmission to humans. One factor is increased exposure of humans to infected rodent excreta. We had received several reports from inhabitants in areas where bank voles normally live that more bank voles were found in traps inside houses than usual. When we investigated the weather conditions during this period, December 2006 was exceptional with respect to the mild weather with no or little snow and hard ice cover in the coastal area of northern Sweden. In Västerbotten County, the average temperature in December was 6.0°C–9.0°C warmer than normal (normally the average temperature in Västerbotten County varies by –4°C along the coast and –13°C in the mountains) The average temperature in Sweden was 4.5°C–9.5°C warmer than normal in December 2006 (Figure 2). The snow cover during winter is important for bank vole survival because bank voles have access to food below the snow and hide from predators and the cold (10). During 2 previous NE peak periods (2001–2002 and 2004–2005), the ground was already covered with snow in early winter (Figure 2). For these reasons, during December 2006, when the ground had no snow cover for 25 of 31 days (Figure 2), bank voles may have sought refuge in barns and houses and other buildings, thereby increasing the exposure for the human population at risk. A concurrent epizootic may have occurred among bank voles, which resulted in larger numbers of infectious animals, as shown in previous rodent studies (11,12). However, we did not have access to rodents during this period and this hypothesis needs to be studied.

Bottom Line: An unexpected and large outbreak of Puumala virus infection in Sweden resulted in 313 nephropathia epidemica patients/100,000 persons in Västerbotten County during 2007.An increase in the rodent population, milder weather, and less snow cover probably contributed to the outbreak.

View Article: PubMed Central - PubMed

Affiliation: Umeå University, Umeå, Sweden.

ABSTRACT
An unexpected and large outbreak of Puumala virus infection in Sweden resulted in 313 nephropathia epidemica patients/100,000 persons in Västerbotten County during 2007. An increase in the rodent population, milder weather, and less snow cover probably contributed to the outbreak.

Show MeSH
Related in: MedlinePlus