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Dengue virus 3 genotype 1 associated with dengue fever and dengue hemorrhagic fever, Brazil.

Barcelos Figueiredo L, Batista Cecílio A, Portela Ferreira G, Paiva Drumond B, Germano de Oliveira J, Bonjardim CA, Peregrino Ferreira PC, Kroon EG - Emerging Infect. Dis. (2008)

Bottom Line: Dengue serotype 3 viruses were isolated from patients in Brazil from 2002 through 2004.On the basis of phylogenetic analyses, these isolates were assigned genotype 1.Its appearance indicates a major risk factor for dengue epidemics and severe disease.

View Article: PubMed Central - PubMed

Affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

ABSTRACT
Dengue serotype 3 viruses were isolated from patients in Brazil from 2002 through 2004. On the basis of phylogenetic analyses, these isolates were assigned genotype 1. This genotype had never been reported in South America before. Its appearance indicates a major risk factor for dengue epidemics and severe disease.

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Related in: MedlinePlus

Location of the city of Belo Horizonte and its boroughs Pampulha, Nordeste, and Noroeste, Minas Gerais State, where samples of dengue virus serotype 3 were collected during 2002–2004.
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Related In: Results  -  Collection


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Figure 1: Location of the city of Belo Horizonte and its boroughs Pampulha, Nordeste, and Noroeste, Minas Gerais State, where samples of dengue virus serotype 3 were collected during 2002–2004.

Mentions: We analyzed the C-prM and the envelope genes of DENV-3 isolates related to different clinical manifestations of dengue disease from Minas Gerais State, Brazil, from 2002 through 2004. Nine acute-phase serum samples from patients with DF or DHF (previously identified by PCR as DENV-3) were selected for this study (Table). All serum samples were from patients living in the city of Belo Horizonte or neighboring cities (Figure 1). Only 1 case-patient (patient MG-20) died.


Dengue virus 3 genotype 1 associated with dengue fever and dengue hemorrhagic fever, Brazil.

Barcelos Figueiredo L, Batista Cecílio A, Portela Ferreira G, Paiva Drumond B, Germano de Oliveira J, Bonjardim CA, Peregrino Ferreira PC, Kroon EG - Emerging Infect. Dis. (2008)

Location of the city of Belo Horizonte and its boroughs Pampulha, Nordeste, and Noroeste, Minas Gerais State, where samples of dengue virus serotype 3 were collected during 2002–2004.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2600180&req=5

Figure 1: Location of the city of Belo Horizonte and its boroughs Pampulha, Nordeste, and Noroeste, Minas Gerais State, where samples of dengue virus serotype 3 were collected during 2002–2004.
Mentions: We analyzed the C-prM and the envelope genes of DENV-3 isolates related to different clinical manifestations of dengue disease from Minas Gerais State, Brazil, from 2002 through 2004. Nine acute-phase serum samples from patients with DF or DHF (previously identified by PCR as DENV-3) were selected for this study (Table). All serum samples were from patients living in the city of Belo Horizonte or neighboring cities (Figure 1). Only 1 case-patient (patient MG-20) died.

Bottom Line: Dengue serotype 3 viruses were isolated from patients in Brazil from 2002 through 2004.On the basis of phylogenetic analyses, these isolates were assigned genotype 1.Its appearance indicates a major risk factor for dengue epidemics and severe disease.

View Article: PubMed Central - PubMed

Affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

ABSTRACT
Dengue serotype 3 viruses were isolated from patients in Brazil from 2002 through 2004. On the basis of phylogenetic analyses, these isolates were assigned genotype 1. This genotype had never been reported in South America before. Its appearance indicates a major risk factor for dengue epidemics and severe disease.

Show MeSH
Related in: MedlinePlus