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Human metapneumovirus infections in children.

Heikkinen T, Osterback R, Peltola V, Jartti T, Vainionpää R - Emerging Infect. Dis. (2008)

Bottom Line: During the epidemic peak, hMPV caused 7.1% of all respiratory infections in the cohort.Acute otitis media developed in 61% of hMPV-infected children <3 years of age.Our findings demonstrate that the effect of hMPV in the community is greatest in children <2 years of age.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Turku University Hospital, Turku, Finland. terho.heikkinen@utu.fi

ABSTRACT
Human metapneumovirus (hMPV) is an important cause of lower respiratory tract infections in hospitalized children, but the age-related incidence and effect of hMPV in unselected children in the community have not been evaluated. We studied a cohort of 1,338 children <13 years of age throughout 1 respiratory season in Finland during 2000-2001. We examined children and obtained a nasal swab for viral detection at any sign of respiratory infection. hMPV was detected in 47 (3.5%) of the 1,338 children. The age-related incidence of hMPV infection was highest (7.6%) in children <2 years of age, in whom hMPV accounted for 1.7% of all infections during the season. During the epidemic peak, hMPV caused 7.1% of all respiratory infections in the cohort. Acute otitis media developed in 61% of hMPV-infected children <3 years of age. Our findings demonstrate that the effect of hMPV in the community is greatest in children <2 years of age.

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Related in: MedlinePlus

Number of children with human metapneumovirus infections during each week of the study period, Finland, 2000–2001.
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Related In: Results  -  Collection


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Figure 1: Number of children with human metapneumovirus infections during each week of the study period, Finland, 2000–2001.

Mentions: The first case of hMPV infection in the study cohort was identified during the week of December 4, 2000, and the last case was identified during the week of April 23, 2001 (Figure 1). hMPV infections were diagnosed weekly over 14 consecutive weeks from January 8, 2001, through April 15, 2001. Overall, hMPV infection was diagnosed in 47 children (26 boys and 21 girls). The median age of the children was 3.0 years; 81% were <5 years of age.


Human metapneumovirus infections in children.

Heikkinen T, Osterback R, Peltola V, Jartti T, Vainionpää R - Emerging Infect. Dis. (2008)

Number of children with human metapneumovirus infections during each week of the study period, Finland, 2000–2001.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2600144&req=5

Figure 1: Number of children with human metapneumovirus infections during each week of the study period, Finland, 2000–2001.
Mentions: The first case of hMPV infection in the study cohort was identified during the week of December 4, 2000, and the last case was identified during the week of April 23, 2001 (Figure 1). hMPV infections were diagnosed weekly over 14 consecutive weeks from January 8, 2001, through April 15, 2001. Overall, hMPV infection was diagnosed in 47 children (26 boys and 21 girls). The median age of the children was 3.0 years; 81% were <5 years of age.

Bottom Line: During the epidemic peak, hMPV caused 7.1% of all respiratory infections in the cohort.Acute otitis media developed in 61% of hMPV-infected children <3 years of age.Our findings demonstrate that the effect of hMPV in the community is greatest in children <2 years of age.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Turku University Hospital, Turku, Finland. terho.heikkinen@utu.fi

ABSTRACT
Human metapneumovirus (hMPV) is an important cause of lower respiratory tract infections in hospitalized children, but the age-related incidence and effect of hMPV in unselected children in the community have not been evaluated. We studied a cohort of 1,338 children <13 years of age throughout 1 respiratory season in Finland during 2000-2001. We examined children and obtained a nasal swab for viral detection at any sign of respiratory infection. hMPV was detected in 47 (3.5%) of the 1,338 children. The age-related incidence of hMPV infection was highest (7.6%) in children <2 years of age, in whom hMPV accounted for 1.7% of all infections during the season. During the epidemic peak, hMPV caused 7.1% of all respiratory infections in the cohort. Acute otitis media developed in 61% of hMPV-infected children <3 years of age. Our findings demonstrate that the effect of hMPV in the community is greatest in children <2 years of age.

Show MeSH
Related in: MedlinePlus