Limits...
Intravascular leiomyosarcoma of the brachiocephalic region -- report of an unusual tumour localisation: case report and review of the literature.

Tilkorn DJ, Lehnhardt M, Hauser J, Daigeler A, Hebebrand D, Mentzel T, Steinau HU, Kuhnen C - World J Surg Oncol (2008)

Bottom Line: A 69-year old patient presented with a biopsy proven leiomyosarcoma of the right supraclavicular region.This may result in an altered surgical strategy.Microthrombembolism and pulmonary metastases may complicate the course of the disease.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Plastic Surgery, Burn Center, Hand Center, Sarcoma Reference Center, BG-University-Hospital Bergmannsheil, Ruhr-University Bochum, Germany. d.tilkorn@web.de

ABSTRACT

Background: Intravascular leiomyosarcoma is a rare tumour entity originating from venous vessel structures and most frequently affecting the inferior vena cava.

Case presentation: A 69-year old patient presented with a biopsy proven leiomyosarcoma of the right supraclavicular region. Tumour resection and histological assessment verified the intravascular tumour origin arising from the internal jugular vein and extending into the surrounding soft tissue.

Conclusion: In the presence of a biopsy proven diagnosis of leiomyosarcoma the rare condition of an intravascular tumour origin has to be considered even without signs of venous stases. This may result in an altered surgical strategy. Microthrombembolism and pulmonary metastases may complicate the course of the disease.

Show MeSH

Related in: MedlinePlus

"Cigar shaped" configurations of tumor cell nuclei of a leiomyosarcoma with nuclear atypia (H&E staining).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC2583979&req=5

Figure 5: "Cigar shaped" configurations of tumor cell nuclei of a leiomyosarcoma with nuclear atypia (H&E staining).

Mentions: Microscopically the spindle-shaped cells of this mesenchymal neoplasm originated from the media of the venous vessel wall (Fig. 4). The tumour cells formed various fascicles interwoven with other longitudinal cross sectional neighbouring fascicles (Fig. 5). The tumour cells were characterized by an eosinophilic cytoplasm and cigar shaped nuclei. The mitotic rate was 19/10 HPF (per high power field). Some foci of tumour necrosis were present.


Intravascular leiomyosarcoma of the brachiocephalic region -- report of an unusual tumour localisation: case report and review of the literature.

Tilkorn DJ, Lehnhardt M, Hauser J, Daigeler A, Hebebrand D, Mentzel T, Steinau HU, Kuhnen C - World J Surg Oncol (2008)

"Cigar shaped" configurations of tumor cell nuclei of a leiomyosarcoma with nuclear atypia (H&E staining).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2583979&req=5

Figure 5: "Cigar shaped" configurations of tumor cell nuclei of a leiomyosarcoma with nuclear atypia (H&E staining).
Mentions: Microscopically the spindle-shaped cells of this mesenchymal neoplasm originated from the media of the venous vessel wall (Fig. 4). The tumour cells formed various fascicles interwoven with other longitudinal cross sectional neighbouring fascicles (Fig. 5). The tumour cells were characterized by an eosinophilic cytoplasm and cigar shaped nuclei. The mitotic rate was 19/10 HPF (per high power field). Some foci of tumour necrosis were present.

Bottom Line: A 69-year old patient presented with a biopsy proven leiomyosarcoma of the right supraclavicular region.This may result in an altered surgical strategy.Microthrombembolism and pulmonary metastases may complicate the course of the disease.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Plastic Surgery, Burn Center, Hand Center, Sarcoma Reference Center, BG-University-Hospital Bergmannsheil, Ruhr-University Bochum, Germany. d.tilkorn@web.de

ABSTRACT

Background: Intravascular leiomyosarcoma is a rare tumour entity originating from venous vessel structures and most frequently affecting the inferior vena cava.

Case presentation: A 69-year old patient presented with a biopsy proven leiomyosarcoma of the right supraclavicular region. Tumour resection and histological assessment verified the intravascular tumour origin arising from the internal jugular vein and extending into the surrounding soft tissue.

Conclusion: In the presence of a biopsy proven diagnosis of leiomyosarcoma the rare condition of an intravascular tumour origin has to be considered even without signs of venous stases. This may result in an altered surgical strategy. Microthrombembolism and pulmonary metastases may complicate the course of the disease.

Show MeSH
Related in: MedlinePlus