Limits...
Spectrocolorimetric evaluation of repaired articular cartilage after a microfracture.

Hattori K, Uematsu K, Matsumori H, Dohi Y, Takakura Y, Ohgushi H - BMC Res Notes (2008)

Bottom Line: In clinical practice, surgeons differentiate color changes in repaired cartilage compared with surrounding intact cartilage, but cannot quantify these color changes.In the L* a* b* colorimetric system, the L* and a* values recovered to close to the values of intact cartilage, whereas the b* value decreased over time after the operation.Our findings demonstrate the ability of spectrocolorimetric measurement to judge the repair cartilage after treatment on the basis of objective data such as the L*, a* and b* values and the SRP as a coincidence index of the spectral reflectance curve.

View Article: PubMed Central - HTML - PubMed

Affiliation: Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology, Amagasaki Site, Amagasaki, Hyogo, Japan. hattori@naramed-u.ac.jp

ABSTRACT

Background: In clinical practice, surgeons differentiate color changes in repaired cartilage compared with surrounding intact cartilage, but cannot quantify these color changes. Objective assessments are required. A spectrocolorimeter was used to evaluate whether intact and repaired cartilage can be quantified.

Findings: We investigated the use of a spectrocolorimeter and the application of two color models (L* a* b* colorimetric system and spectral reflectance distribution) to describe and quantify articular cartilage. In this study, we measured the colors of intact and repaired cartilage after a microfracture. Histologically, the repaired cartilage was a mixture of fibrocartilage and hyaline cartilage. In the L* a* b* colorimetric system, the L* and a* values recovered to close to the values of intact cartilage, whereas the b* value decreased over time after the operation. Regarding the spectral reflectance distribution at 12 weeks after the operation, the repaired cartilage had a higher spectral reflectance ratio than intact cartilage between wavelengths of 400 to 470 nm.

Conclusion: This study reports the first results regarding the relationship between spectrocolorimetric evaluation and the histological findings of repair cartilage after a microfracture. Our findings demonstrate the ability of spectrocolorimetric measurement to judge the repair cartilage after treatment on the basis of objective data such as the L*, a* and b* values and the SRP as a coincidence index of the spectral reflectance curve.

No MeSH data available.


Related in: MedlinePlus

The L*, a* and b* values of the four experimental models. Error bars represent the standard deviation of each group. *P < 0.05 vs. the control group (Group C) by the non-parametric Mann-Whitney U-test.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC2570674&req=5

Figure 1: The L*, a* and b* values of the four experimental models. Error bars represent the standard deviation of each group. *P < 0.05 vs. the control group (Group C) by the non-parametric Mann-Whitney U-test.

Mentions: The differences in the L*, a* and b* values of intact and repaired cartilage are shown in Figure 1. The L* value was decreased at 2 weeks after the operation compared with the control value, and then gradually increased from 4 to 12 weeks after the operation. The a* value was increased at 2 weeks but then decreased to a value close to the control value at 12 weeks. The b* value was not significantly changed at 2 weeks compared with the control value, and then remarkably declined from 4 to 12 weeks.


Spectrocolorimetric evaluation of repaired articular cartilage after a microfracture.

Hattori K, Uematsu K, Matsumori H, Dohi Y, Takakura Y, Ohgushi H - BMC Res Notes (2008)

The L*, a* and b* values of the four experimental models. Error bars represent the standard deviation of each group. *P < 0.05 vs. the control group (Group C) by the non-parametric Mann-Whitney U-test.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2570674&req=5

Figure 1: The L*, a* and b* values of the four experimental models. Error bars represent the standard deviation of each group. *P < 0.05 vs. the control group (Group C) by the non-parametric Mann-Whitney U-test.
Mentions: The differences in the L*, a* and b* values of intact and repaired cartilage are shown in Figure 1. The L* value was decreased at 2 weeks after the operation compared with the control value, and then gradually increased from 4 to 12 weeks after the operation. The a* value was increased at 2 weeks but then decreased to a value close to the control value at 12 weeks. The b* value was not significantly changed at 2 weeks compared with the control value, and then remarkably declined from 4 to 12 weeks.

Bottom Line: In clinical practice, surgeons differentiate color changes in repaired cartilage compared with surrounding intact cartilage, but cannot quantify these color changes.In the L* a* b* colorimetric system, the L* and a* values recovered to close to the values of intact cartilage, whereas the b* value decreased over time after the operation.Our findings demonstrate the ability of spectrocolorimetric measurement to judge the repair cartilage after treatment on the basis of objective data such as the L*, a* and b* values and the SRP as a coincidence index of the spectral reflectance curve.

View Article: PubMed Central - HTML - PubMed

Affiliation: Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology, Amagasaki Site, Amagasaki, Hyogo, Japan. hattori@naramed-u.ac.jp

ABSTRACT

Background: In clinical practice, surgeons differentiate color changes in repaired cartilage compared with surrounding intact cartilage, but cannot quantify these color changes. Objective assessments are required. A spectrocolorimeter was used to evaluate whether intact and repaired cartilage can be quantified.

Findings: We investigated the use of a spectrocolorimeter and the application of two color models (L* a* b* colorimetric system and spectral reflectance distribution) to describe and quantify articular cartilage. In this study, we measured the colors of intact and repaired cartilage after a microfracture. Histologically, the repaired cartilage was a mixture of fibrocartilage and hyaline cartilage. In the L* a* b* colorimetric system, the L* and a* values recovered to close to the values of intact cartilage, whereas the b* value decreased over time after the operation. Regarding the spectral reflectance distribution at 12 weeks after the operation, the repaired cartilage had a higher spectral reflectance ratio than intact cartilage between wavelengths of 400 to 470 nm.

Conclusion: This study reports the first results regarding the relationship between spectrocolorimetric evaluation and the histological findings of repair cartilage after a microfracture. Our findings demonstrate the ability of spectrocolorimetric measurement to judge the repair cartilage after treatment on the basis of objective data such as the L*, a* and b* values and the SRP as a coincidence index of the spectral reflectance curve.

No MeSH data available.


Related in: MedlinePlus