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Juvenile polyposis syndrome affecting the stomach: a case report.

Kelly S, Dwerryhouse S, Safranek P, Hardwick R - J Med Case Rep (2008)

Bottom Line: Hamartomatous polyps can affect the entire gastrointestinal tract but usually predominate in the colon.A 51-year-old man presented with symptoms of gastric outlet obstruction and upper gastrointestinal bleeding.This case illustrates important principles in managing this condition.

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Affiliation: Cambridge Oesophagogastric surgery centre, Addenbrookes hospital, Cambridge, UK. stevekelly999@btinternet.com

ABSTRACT

Introduction: Juvenile polyposis syndrome(JPS) is a rare autosomal dominant inherited condition. Hamartomatous polyps can affect the entire gastrointestinal tract but usually predominate in the colon. In this case report we present an unusual case of JPS that presented with massive gastric polyposis requiring a total gastrectomy.

Case presentation: A 51-year-old man presented with symptoms of gastric outlet obstruction and upper gastrointestinal bleeding. Gastroscopy showed massive gastric polyposis with a large antral polyp that had prolapsed through the pylorus causing gastric outlet obstruction. Initially endoscopic polypectomy was performed, but due to progressive symptoms a total gastrectomy was then performed. Histology confirmed massive gastric juvenile polyposis.

Conclusion: Massive gastric polyposis is an uncommon manifestation of juvenile polyposis syndrome. This case illustrates important principles in managing this condition.

No MeSH data available.


Related in: MedlinePlus

Histology of juvenile polyp showing characteristic features of dense stroma and dilated cystic spaces.
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Figure 3: Histology of juvenile polyp showing characteristic features of dense stroma and dilated cystic spaces.

Mentions: Histology of the surgical specimen showed massive juvenile gastric polyposis (figure 3). There was focal intestinal metaplasia and mild dyplasia. No evidence of malignancy was found.


Juvenile polyposis syndrome affecting the stomach: a case report.

Kelly S, Dwerryhouse S, Safranek P, Hardwick R - J Med Case Rep (2008)

Histology of juvenile polyp showing characteristic features of dense stroma and dilated cystic spaces.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2567337&req=5

Figure 3: Histology of juvenile polyp showing characteristic features of dense stroma and dilated cystic spaces.
Mentions: Histology of the surgical specimen showed massive juvenile gastric polyposis (figure 3). There was focal intestinal metaplasia and mild dyplasia. No evidence of malignancy was found.

Bottom Line: Hamartomatous polyps can affect the entire gastrointestinal tract but usually predominate in the colon.A 51-year-old man presented with symptoms of gastric outlet obstruction and upper gastrointestinal bleeding.This case illustrates important principles in managing this condition.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cambridge Oesophagogastric surgery centre, Addenbrookes hospital, Cambridge, UK. stevekelly999@btinternet.com

ABSTRACT

Introduction: Juvenile polyposis syndrome(JPS) is a rare autosomal dominant inherited condition. Hamartomatous polyps can affect the entire gastrointestinal tract but usually predominate in the colon. In this case report we present an unusual case of JPS that presented with massive gastric polyposis requiring a total gastrectomy.

Case presentation: A 51-year-old man presented with symptoms of gastric outlet obstruction and upper gastrointestinal bleeding. Gastroscopy showed massive gastric polyposis with a large antral polyp that had prolapsed through the pylorus causing gastric outlet obstruction. Initially endoscopic polypectomy was performed, but due to progressive symptoms a total gastrectomy was then performed. Histology confirmed massive gastric juvenile polyposis.

Conclusion: Massive gastric polyposis is an uncommon manifestation of juvenile polyposis syndrome. This case illustrates important principles in managing this condition.

No MeSH data available.


Related in: MedlinePlus