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Acute liver failure due to primary angiosarcoma: a case report and review of literature.

Bhati CS, Bhatt AN, Starkey G, Hubscher SG, Bramhall SR - World J Surg Oncol (2008)

Bottom Line: Acute liver failure is an extremely rare presentation of a primary liver tumour.We report a case of a seventy year-old man who presented with a very short period of jaundice leading to fulminant hepatic failure (FHF).On further investigation he was found to have primary angiosarcoma of liver.

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Affiliation: Liver Unit, Queen Elizabeth Hospital, Birmingham, UK. c.s.bhati@bham.ac.uk

ABSTRACT

Background: Hepatic angiosarcoma is a primary sarcoma of the liver, accounting for only 2% of all primary hepatic malignancies. Acute liver failure is an extremely rare presentation of a primary liver tumour.

Case presentation: We report a case of a seventy year-old man who presented with a very short period of jaundice leading to fulminant hepatic failure (FHF). On further investigation he was found to have primary angiosarcoma of liver.

Conclusion: The treatment outcomes for hepatic angiosarcoma are poor, we discuss the options available and the need for prompt investigation and establishment of a diagnosis.

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Abdominal CT scan showing complete replacement of liver parenchyma with liver tumour.
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Figure 1: Abdominal CT scan showing complete replacement of liver parenchyma with liver tumour.

Mentions: An urgent ultrasound scan demonstrated hepatomegaly with significant liver paranchymal alteration. A subsequent contrast enhanced abdominal CT showed gross replacement of liver with tumour tissue suggestive of a primary liver tumour (Figure 1). The patient was at this point referred to our centre.


Acute liver failure due to primary angiosarcoma: a case report and review of literature.

Bhati CS, Bhatt AN, Starkey G, Hubscher SG, Bramhall SR - World J Surg Oncol (2008)

Abdominal CT scan showing complete replacement of liver parenchyma with liver tumour.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2567320&req=5

Figure 1: Abdominal CT scan showing complete replacement of liver parenchyma with liver tumour.
Mentions: An urgent ultrasound scan demonstrated hepatomegaly with significant liver paranchymal alteration. A subsequent contrast enhanced abdominal CT showed gross replacement of liver with tumour tissue suggestive of a primary liver tumour (Figure 1). The patient was at this point referred to our centre.

Bottom Line: Acute liver failure is an extremely rare presentation of a primary liver tumour.We report a case of a seventy year-old man who presented with a very short period of jaundice leading to fulminant hepatic failure (FHF).On further investigation he was found to have primary angiosarcoma of liver.

View Article: PubMed Central - HTML - PubMed

Affiliation: Liver Unit, Queen Elizabeth Hospital, Birmingham, UK. c.s.bhati@bham.ac.uk

ABSTRACT

Background: Hepatic angiosarcoma is a primary sarcoma of the liver, accounting for only 2% of all primary hepatic malignancies. Acute liver failure is an extremely rare presentation of a primary liver tumour.

Case presentation: We report a case of a seventy year-old man who presented with a very short period of jaundice leading to fulminant hepatic failure (FHF). On further investigation he was found to have primary angiosarcoma of liver.

Conclusion: The treatment outcomes for hepatic angiosarcoma are poor, we discuss the options available and the need for prompt investigation and establishment of a diagnosis.

Show MeSH
Related in: MedlinePlus