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Hypertrophic pulmonary osteoarthropathy secondary to bronchial adenocarcinoma and coexisting pulmonary tuberculosis: a case report.

Ntaios G, Adamidou A, Karamitsos D - Cases J (2008)

Bottom Line: Ten months later, he returned with metastatic lesions in the brain and the adrenals.A few days later, he died.The patient suffered from bronchial adenocarcinoma as well as pulmonary tuberculosis.As a complication of these two coexisting conditions, the patient developed hypertrophic pulmonary osteoarthropathy.

View Article: PubMed Central - HTML - PubMed

Affiliation: First Propedeutic Department of Internal Medicine, AHEPA Hospital, Aristotle University, Thessaloniki, Greece. ntaiosgeorge@yahoo.gr.

ABSTRACT
A 44-year-old man presented with painful swelling of wrists and ankles, severe pain at both tibiae, clubbing of fingers and toes and arthritis in wrist and ankle joints. The chest roentgenogram showed consolidation of the right lower lobe, whereas plain roentgenograms revealed solid periosteal reaction at both tibiae. CT and bronchoscopy confirmed the presence of adenocarcinoma of the right lower lobe. Moreover, mycobacterium of tuberculosis was isolated by culture of the patient's sputum.Our patient received antituberculous treatment and soon he underwent surgical excision of the tumour and subsequent chemotherapy. Ten months later, he returned with metastatic lesions in the brain and the adrenals. A few days later, he died.The patient suffered from bronchial adenocarcinoma as well as pulmonary tuberculosis. As a complication of these two coexisting conditions, the patient developed hypertrophic pulmonary osteoarthropathy.

No MeSH data available.


Related in: MedlinePlus

Finger clubbing.
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Figure 1: Finger clubbing.

Mentions: A 44-year-old man was admitted in our clinic due to high fever and painful swelling of wrists and ankles for four months prior to admission. He also complained of severe pain at his tibiae. He was a heavy smoker (50 pack-years) and he denied any chronic illness. At admission, clinical examination revealed a severely ill patient who was unable to walk due to extreme leg pain. He was febrile (39°C) and arthritis of wrists and ankles could be easily noticed. Moreover, clubbing of the fingers was evident (figure 1).


Hypertrophic pulmonary osteoarthropathy secondary to bronchial adenocarcinoma and coexisting pulmonary tuberculosis: a case report.

Ntaios G, Adamidou A, Karamitsos D - Cases J (2008)

Finger clubbing.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2567299&req=5

Figure 1: Finger clubbing.
Mentions: A 44-year-old man was admitted in our clinic due to high fever and painful swelling of wrists and ankles for four months prior to admission. He also complained of severe pain at his tibiae. He was a heavy smoker (50 pack-years) and he denied any chronic illness. At admission, clinical examination revealed a severely ill patient who was unable to walk due to extreme leg pain. He was febrile (39°C) and arthritis of wrists and ankles could be easily noticed. Moreover, clubbing of the fingers was evident (figure 1).

Bottom Line: Ten months later, he returned with metastatic lesions in the brain and the adrenals.A few days later, he died.The patient suffered from bronchial adenocarcinoma as well as pulmonary tuberculosis.As a complication of these two coexisting conditions, the patient developed hypertrophic pulmonary osteoarthropathy.

View Article: PubMed Central - HTML - PubMed

Affiliation: First Propedeutic Department of Internal Medicine, AHEPA Hospital, Aristotle University, Thessaloniki, Greece. ntaiosgeorge@yahoo.gr.

ABSTRACT
A 44-year-old man presented with painful swelling of wrists and ankles, severe pain at both tibiae, clubbing of fingers and toes and arthritis in wrist and ankle joints. The chest roentgenogram showed consolidation of the right lower lobe, whereas plain roentgenograms revealed solid periosteal reaction at both tibiae. CT and bronchoscopy confirmed the presence of adenocarcinoma of the right lower lobe. Moreover, mycobacterium of tuberculosis was isolated by culture of the patient's sputum.Our patient received antituberculous treatment and soon he underwent surgical excision of the tumour and subsequent chemotherapy. Ten months later, he returned with metastatic lesions in the brain and the adrenals. A few days later, he died.The patient suffered from bronchial adenocarcinoma as well as pulmonary tuberculosis. As a complication of these two coexisting conditions, the patient developed hypertrophic pulmonary osteoarthropathy.

No MeSH data available.


Related in: MedlinePlus