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The burden of trachoma in Ayod County of Southern Sudan.

King JD, Ngondi J, Gatpan G, Lopidia B, Becknell S, Emerson PM - PLoS Negl Trop Dis (2008)

Bottom Line: Prevalence of trachomatous trichiasis (TT) was 14.6% (95% CI, 10.9-18.3) in adults over 14 years of age; 2.9% (95% CI, 0.4-5.3) in children 1-14 years of age; and 8.4% (95% CI, 5.5-11.3) overall.The prevalence of corneal opacity in persons over 14 years of age with TT was 6.4% (95% CI, 4.5-8.3).The high prevalence of active trachoma and trichiasis confirms the severe burden of blinding trachoma found in other post-conflict areas of Southern Sudan.

View Article: PubMed Central - PubMed

Affiliation: The Carter Center, Atlanta, Georgia, USA. jonathan.king@emory.edu

ABSTRACT

Background: Blindness due to trachoma is avoidable through Surgery, Antibiotics, Facial hygiene and Environmental improvements (SAFE). Recent surveys have shown trachoma to be a serious cause of blindness in Southern Sudan. We conducted this survey in Ayod County of Jonglei State to estimate the need for intervention activities to eliminate blinding trachoma.

Methodology and findings: A cross-sectional two-stage cluster random survey was conducted in November 2006. All residents of selected households were clinically assessed for trachoma using the World Health Organization (WHO) simplified grading scheme. A total of 2,335 people from 392 households were examined, of whom 1,107 were over 14 years of age. Prevalence of signs of active trachoma in children 1-9 years of age was: trachomatous inflammation follicular (TF) = 80.1% (95% confidence interval [CI], 73.9-86.3); trachomatous inflammation intense (TI) = 60.7% (95% CI, 54.6-66.8); and TF and/or TI (active trachoma) = 88.3% (95% CI, 83.7-92.9). Prevalence of trachomatous trichiasis (TT) was 14.6% (95% CI, 10.9-18.3) in adults over 14 years of age; 2.9% (95% CI, 0.4-5.3) in children 1-14 years of age; and 8.4% (95% CI, 5.5-11.3) overall. The prevalence of corneal opacity in persons over 14 years of age with TT was 6.4% (95% CI, 4.5-8.3). No statistically significant difference was observed in the prevalence of trachoma signs between genders. Trachoma affected almost all households surveyed: 384/392 (98.0%) had at least one person with active trachoma and 130 (33.2%) had at least one person with trichiasis.

Conclusions: Trachoma is an unnecessary public health problem in Ayod. The high prevalence of active trachoma and trichiasis confirms the severe burden of blinding trachoma found in other post-conflict areas of Southern Sudan. Based on WHO recommended thresholds, all aspects of the SAFE strategy are indicated to eliminate blinding trachoma in Ayod.

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Related in: MedlinePlus

Map of Southern Sudan showing survey site (Ayod County), and areas where previous surveys have been conducted and key prevalence indicators for trachoma.TF, Prevalence of trachomatous inflammation-follicular in children aged 1–9 years; TF/TI, Prevalence of trachomatous inflammation-follicular and or trachomatous inflammation-intense in children aged 1–9 years; TT, Prevalence of trachomatous trichiasis in persons aged 15 years and above.
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pntd-0000299-g001: Map of Southern Sudan showing survey site (Ayod County), and areas where previous surveys have been conducted and key prevalence indicators for trachoma.TF, Prevalence of trachomatous inflammation-follicular in children aged 1–9 years; TF/TI, Prevalence of trachomatous inflammation-follicular and or trachomatous inflammation-intense in children aged 1–9 years; TT, Prevalence of trachomatous trichiasis in persons aged 15 years and above.

Mentions: Conceived and designed the experiments: JDK JN GG BL SB PME. Performed the experiments: JDK JN GG BL PME. Analyzed the data: JDK. Wrote the paper: JDK. Supervised the data analysis, developed Figure 1, and contributed to the editing of the paper: JN. Contributed to the editing of the paper: GG BL SB. Supervised the experiments and contributed greatly to the editing of the paper: PME.


The burden of trachoma in Ayod County of Southern Sudan.

King JD, Ngondi J, Gatpan G, Lopidia B, Becknell S, Emerson PM - PLoS Negl Trop Dis (2008)

Map of Southern Sudan showing survey site (Ayod County), and areas where previous surveys have been conducted and key prevalence indicators for trachoma.TF, Prevalence of trachomatous inflammation-follicular in children aged 1–9 years; TF/TI, Prevalence of trachomatous inflammation-follicular and or trachomatous inflammation-intense in children aged 1–9 years; TT, Prevalence of trachomatous trichiasis in persons aged 15 years and above.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2553487&req=5

pntd-0000299-g001: Map of Southern Sudan showing survey site (Ayod County), and areas where previous surveys have been conducted and key prevalence indicators for trachoma.TF, Prevalence of trachomatous inflammation-follicular in children aged 1–9 years; TF/TI, Prevalence of trachomatous inflammation-follicular and or trachomatous inflammation-intense in children aged 1–9 years; TT, Prevalence of trachomatous trichiasis in persons aged 15 years and above.
Mentions: Conceived and designed the experiments: JDK JN GG BL SB PME. Performed the experiments: JDK JN GG BL PME. Analyzed the data: JDK. Wrote the paper: JDK. Supervised the data analysis, developed Figure 1, and contributed to the editing of the paper: JN. Contributed to the editing of the paper: GG BL SB. Supervised the experiments and contributed greatly to the editing of the paper: PME.

Bottom Line: Prevalence of trachomatous trichiasis (TT) was 14.6% (95% CI, 10.9-18.3) in adults over 14 years of age; 2.9% (95% CI, 0.4-5.3) in children 1-14 years of age; and 8.4% (95% CI, 5.5-11.3) overall.The prevalence of corneal opacity in persons over 14 years of age with TT was 6.4% (95% CI, 4.5-8.3).The high prevalence of active trachoma and trichiasis confirms the severe burden of blinding trachoma found in other post-conflict areas of Southern Sudan.

View Article: PubMed Central - PubMed

Affiliation: The Carter Center, Atlanta, Georgia, USA. jonathan.king@emory.edu

ABSTRACT

Background: Blindness due to trachoma is avoidable through Surgery, Antibiotics, Facial hygiene and Environmental improvements (SAFE). Recent surveys have shown trachoma to be a serious cause of blindness in Southern Sudan. We conducted this survey in Ayod County of Jonglei State to estimate the need for intervention activities to eliminate blinding trachoma.

Methodology and findings: A cross-sectional two-stage cluster random survey was conducted in November 2006. All residents of selected households were clinically assessed for trachoma using the World Health Organization (WHO) simplified grading scheme. A total of 2,335 people from 392 households were examined, of whom 1,107 were over 14 years of age. Prevalence of signs of active trachoma in children 1-9 years of age was: trachomatous inflammation follicular (TF) = 80.1% (95% confidence interval [CI], 73.9-86.3); trachomatous inflammation intense (TI) = 60.7% (95% CI, 54.6-66.8); and TF and/or TI (active trachoma) = 88.3% (95% CI, 83.7-92.9). Prevalence of trachomatous trichiasis (TT) was 14.6% (95% CI, 10.9-18.3) in adults over 14 years of age; 2.9% (95% CI, 0.4-5.3) in children 1-14 years of age; and 8.4% (95% CI, 5.5-11.3) overall. The prevalence of corneal opacity in persons over 14 years of age with TT was 6.4% (95% CI, 4.5-8.3). No statistically significant difference was observed in the prevalence of trachoma signs between genders. Trachoma affected almost all households surveyed: 384/392 (98.0%) had at least one person with active trachoma and 130 (33.2%) had at least one person with trichiasis.

Conclusions: Trachoma is an unnecessary public health problem in Ayod. The high prevalence of active trachoma and trichiasis confirms the severe burden of blinding trachoma found in other post-conflict areas of Southern Sudan. Based on WHO recommended thresholds, all aspects of the SAFE strategy are indicated to eliminate blinding trachoma in Ayod.

Show MeSH
Related in: MedlinePlus