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Mediastinal plasmacytoma with multiple myeloma presenting as a diagnostic dilemma.

Masood A, Hudhud KH, Hegazi A, Syed G - Cases J (2008)

Bottom Line: Most extramedullary Plasmacytomas are associated with the upper respiratory tract.The mediastinum is rarely involved.The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cancer care center of Frederick, Frederick, MD, USA. ashiqmsd@gmail.com.

ABSTRACT
Plasmacytoma are extramedullary accumulations of plasma cells. Most extramedullary Plasmacytomas are associated with the upper respiratory tract. The mediastinum is rarely involved. We report a rare case of mediastinal plasmacytoma with multiple myeloma. The patient is 66 year old woman presented with bone pains and mediastinal mass on CT scan and MRI. The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

No MeSH data available.


Related in: MedlinePlus

H&E stain illustrating trilineage hematopoiesis.
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Figure 3: H&E stain illustrating trilineage hematopoiesis.

Mentions: The patient underwent biopsy of mediastinal mass, which was found to be consistent with plasmacytoma (lambda light chain restricted). A bone marrow examination showed marrow involvement by plasma cell neoplasm (Overall 10% of the total cellularity). Figure 3, 4, and 5


Mediastinal plasmacytoma with multiple myeloma presenting as a diagnostic dilemma.

Masood A, Hudhud KH, Hegazi A, Syed G - Cases J (2008)

H&E stain illustrating trilineage hematopoiesis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2533298&req=5

Figure 3: H&E stain illustrating trilineage hematopoiesis.
Mentions: The patient underwent biopsy of mediastinal mass, which was found to be consistent with plasmacytoma (lambda light chain restricted). A bone marrow examination showed marrow involvement by plasma cell neoplasm (Overall 10% of the total cellularity). Figure 3, 4, and 5

Bottom Line: Most extramedullary Plasmacytomas are associated with the upper respiratory tract.The mediastinum is rarely involved.The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cancer care center of Frederick, Frederick, MD, USA. ashiqmsd@gmail.com.

ABSTRACT
Plasmacytoma are extramedullary accumulations of plasma cells. Most extramedullary Plasmacytomas are associated with the upper respiratory tract. The mediastinum is rarely involved. We report a rare case of mediastinal plasmacytoma with multiple myeloma. The patient is 66 year old woman presented with bone pains and mediastinal mass on CT scan and MRI. The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

No MeSH data available.


Related in: MedlinePlus