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Mediastinal plasmacytoma with multiple myeloma presenting as a diagnostic dilemma.

Masood A, Hudhud KH, Hegazi A, Syed G - Cases J (2008)

Bottom Line: Most extramedullary Plasmacytomas are associated with the upper respiratory tract.The mediastinum is rarely involved.The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cancer care center of Frederick, Frederick, MD, USA. ashiqmsd@gmail.com.

ABSTRACT
Plasmacytoma are extramedullary accumulations of plasma cells. Most extramedullary Plasmacytomas are associated with the upper respiratory tract. The mediastinum is rarely involved. We report a rare case of mediastinal plasmacytoma with multiple myeloma. The patient is 66 year old woman presented with bone pains and mediastinal mass on CT scan and MRI. The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

No MeSH data available.


Related in: MedlinePlus

PET scan showing hypermetabolic activity in azygoesophageal recess and right 8th rib.
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Figure 2: PET scan showing hypermetabolic activity in azygoesophageal recess and right 8th rib.

Mentions: The MRI showed 3.9 × 4.2 cms mass in azygoesophageal recess, the pathologic fracture of 8th right rib, abnormal bone marrow signal in multiple areas of right sacroiliac joint, left superior acetabulum, and right greater trochanter. The PET scan confirmed these findings with uptake in all of these regions (Figure 2).


Mediastinal plasmacytoma with multiple myeloma presenting as a diagnostic dilemma.

Masood A, Hudhud KH, Hegazi A, Syed G - Cases J (2008)

PET scan showing hypermetabolic activity in azygoesophageal recess and right 8th rib.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2533298&req=5

Figure 2: PET scan showing hypermetabolic activity in azygoesophageal recess and right 8th rib.
Mentions: The MRI showed 3.9 × 4.2 cms mass in azygoesophageal recess, the pathologic fracture of 8th right rib, abnormal bone marrow signal in multiple areas of right sacroiliac joint, left superior acetabulum, and right greater trochanter. The PET scan confirmed these findings with uptake in all of these regions (Figure 2).

Bottom Line: Most extramedullary Plasmacytomas are associated with the upper respiratory tract.The mediastinum is rarely involved.The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cancer care center of Frederick, Frederick, MD, USA. ashiqmsd@gmail.com.

ABSTRACT
Plasmacytoma are extramedullary accumulations of plasma cells. Most extramedullary Plasmacytomas are associated with the upper respiratory tract. The mediastinum is rarely involved. We report a rare case of mediastinal plasmacytoma with multiple myeloma. The patient is 66 year old woman presented with bone pains and mediastinal mass on CT scan and MRI. The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

No MeSH data available.


Related in: MedlinePlus