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Mediastinal plasmacytoma with multiple myeloma presenting as a diagnostic dilemma.

Masood A, Hudhud KH, Hegazi A, Syed G - Cases J (2008)

Bottom Line: Most extramedullary Plasmacytomas are associated with the upper respiratory tract.The mediastinum is rarely involved.The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cancer care center of Frederick, Frederick, MD, USA. ashiqmsd@gmail.com.

ABSTRACT
Plasmacytoma are extramedullary accumulations of plasma cells. Most extramedullary Plasmacytomas are associated with the upper respiratory tract. The mediastinum is rarely involved. We report a rare case of mediastinal plasmacytoma with multiple myeloma. The patient is 66 year old woman presented with bone pains and mediastinal mass on CT scan and MRI. The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

No MeSH data available.


Related in: MedlinePlus

CT scan of chest showing mediastinal mass and pathological fracture of the right 8th rib.
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Figure 1: CT scan of chest showing mediastinal mass and pathological fracture of the right 8th rib.

Mentions: A 66 year old lady referred to our oncology clinic for the management of mediastinal mass. Two weeks prior to her visit, she started with severe low back pain radiating to lower extremities, nausea, retching, and mild dyspnea. She was admitted in the hospital, thorough investigation revealed mediastinal mass on CT scan (Figure 1). MRI of spine showed L4–L5 disc herniation along with significant spinal canal stenosis. She received treatment and was discharged in stable condition after 5 days of admission.


Mediastinal plasmacytoma with multiple myeloma presenting as a diagnostic dilemma.

Masood A, Hudhud KH, Hegazi A, Syed G - Cases J (2008)

CT scan of chest showing mediastinal mass and pathological fracture of the right 8th rib.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2533298&req=5

Figure 1: CT scan of chest showing mediastinal mass and pathological fracture of the right 8th rib.
Mentions: A 66 year old lady referred to our oncology clinic for the management of mediastinal mass. Two weeks prior to her visit, she started with severe low back pain radiating to lower extremities, nausea, retching, and mild dyspnea. She was admitted in the hospital, thorough investigation revealed mediastinal mass on CT scan (Figure 1). MRI of spine showed L4–L5 disc herniation along with significant spinal canal stenosis. She received treatment and was discharged in stable condition after 5 days of admission.

Bottom Line: Most extramedullary Plasmacytomas are associated with the upper respiratory tract.The mediastinum is rarely involved.The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cancer care center of Frederick, Frederick, MD, USA. ashiqmsd@gmail.com.

ABSTRACT
Plasmacytoma are extramedullary accumulations of plasma cells. Most extramedullary Plasmacytomas are associated with the upper respiratory tract. The mediastinum is rarely involved. We report a rare case of mediastinal plasmacytoma with multiple myeloma. The patient is 66 year old woman presented with bone pains and mediastinal mass on CT scan and MRI. The preliminary diagnosis of occult lung cancer with mediastinal involvement, and widespread skeletal metastasis was made, although lymphoproliferative disorder along with germ cell tumor was also kept in differentials.The diagnosis of mediastinal plasmacytoma with multiple myeloma was made after extensive investigations.

No MeSH data available.


Related in: MedlinePlus