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Histological variants of cutaneous Kaposi sarcoma.

Grayson W, Pantanowitz L - Diagn Pathol (2008)

Bottom Line: This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions.Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS.Involuting lesions as a result of treatment related regression are also presented.

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Affiliation: Histopathology Department, Ampath National Laboratory Support Services, Johannesburg, South Africa. wayne.grayson@live.com

ABSTRACT
This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS. Involuting lesions as a result of treatment related regression are also presented.

No MeSH data available.


Related in: MedlinePlus

Pyogenic granuloma-like Kaposi sarcoma manifesting as an exophytic mass enveloped by an epidermal collarette (H&E stain).
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Figure 17: Pyogenic granuloma-like Kaposi sarcoma manifesting as an exophytic mass enveloped by an epidermal collarette (H&E stain).

Mentions: Small, superficially located nodular or micronodular KS lesions may be protuberant and thereby elicit the development of a peripheral epidermal collarette (Figure 17). Such lesions have been referred to as pyogenic granuloma (PG)-like KS [48]. Traumatized lesions may undergo ulceration and become inflamed, and potentially misdiagnosed as a true PG (lobular capillary hemangioma). To further complicate matters true PGs may themselves harbor kaposiform areas. PG-like KS must also be distinguished from bacillary angiomatosis, as some examples of the latter can adopt striking PG-like low-power architecture [14,15].


Histological variants of cutaneous Kaposi sarcoma.

Grayson W, Pantanowitz L - Diagn Pathol (2008)

Pyogenic granuloma-like Kaposi sarcoma manifesting as an exophytic mass enveloped by an epidermal collarette (H&E stain).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2526984&req=5

Figure 17: Pyogenic granuloma-like Kaposi sarcoma manifesting as an exophytic mass enveloped by an epidermal collarette (H&E stain).
Mentions: Small, superficially located nodular or micronodular KS lesions may be protuberant and thereby elicit the development of a peripheral epidermal collarette (Figure 17). Such lesions have been referred to as pyogenic granuloma (PG)-like KS [48]. Traumatized lesions may undergo ulceration and become inflamed, and potentially misdiagnosed as a true PG (lobular capillary hemangioma). To further complicate matters true PGs may themselves harbor kaposiform areas. PG-like KS must also be distinguished from bacillary angiomatosis, as some examples of the latter can adopt striking PG-like low-power architecture [14,15].

Bottom Line: This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions.Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS.Involuting lesions as a result of treatment related regression are also presented.

View Article: PubMed Central - HTML - PubMed

Affiliation: Histopathology Department, Ampath National Laboratory Support Services, Johannesburg, South Africa. wayne.grayson@live.com

ABSTRACT
This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS. Involuting lesions as a result of treatment related regression are also presented.

No MeSH data available.


Related in: MedlinePlus